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| Name: |
RTW INVESTMENTS LLC |
| City: |
NEW YORK |
| State: |
NY |
| Zip: |
10019 |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
MDGL |
Madrigal Pharmaceuticals Inc |
1 |
- |
$300.16 |
$660,369,000 |
1,993,687 |
10.1% |
45,177,000 |
0 |
7.755 |
Diagnostic Substances |
|
|
ARGX |
Argenx Se |
2 |
- |
$542.47 |
$398,619,000 |
673,497 |
6.1% |
-15,582,000 |
0 |
1.433 |
N/A |
|
|
PTCT |
PTC Therapeutics, Inc. |
3 |
- |
$48.59 |
$381,340,000 |
7,483,127 |
5.83% |
47,614,000 |
90,000 |
8.264 |
Biotechnology |
|
|
NTRA |
Natera, Inc. |
4 |
- |
$160.72 |
$366,753,000 |
2,593,546 |
5.61% |
-43,770,000 |
223 |
2.097 |
N/A |
|
|
AXSM |
Axsome Therapeutics, Inc. |
5 |
- |
$102.97 |
$340,878,000 |
2,922,729 |
5.21% |
-1,908,000 |
-1,128,636 |
6.177 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
6 |
- |
$0.00 |
$300,335,000 |
7,419,340 |
4.59% |
109,495,000 |
559,517 |
9.836 |
N/A |
|
|
PTGX |
Protagonist Therapeutics, Inc |
7 |
- |
$50.21 |
$276,591,000 |
5,719,415 |
4.23% |
64,347,000 |
220,870 |
8.944 |
N/A |
|
|
RNA |
Avidity Biosciences, Inc. |
8 |
- |
$28.46 |
$258,209,000 |
8,746,926 |
3.95% |
27,521,000 |
814,056 |
6.479 |
N/A |
|
|
PEN |
Penumbra Inc |
9 |
- |
$250.68 |
$230,713,000 |
862,770 |
3.53% |
25,898,000 |
320 |
2.376 |
N/A |
|
|
INSM |
Insmed Inc |
10 |
- |
$97.62 |
$229,981,000 |
3,014,558 |
3.52% |
21,856,000 |
0 |
1.587 |
Biotechnology |
|
|
ALKS |
Alkermes Plc |
11 |
- |
$28.99 |
$227,333,000 |
6,884,698 |
3.48% |
9,970,000 |
-673,137 |
3.748 |
Drug Delivery |
|
|
SYK |
Stryker Corp |
12 |
- |
$396.74 |
$219,710,000 |
590,221 |
3.36% |
7,201,000 |
0 |
0.157 |
Medical Instruments &... |
|
|
VRNA |
Verona Pharma Plc |
13 |
- |
$0.00 |
$180,870,000 |
2,848,800 |
2.77% |
96,302,000 |
1,027,781 |
3.531 |
N/A |
|
|
MRUS |
Merus Nv |
14 |
- |
$52.66 |
$175,490,000 |
4,169,393 |
2.68% |
167,000 |
0 |
5.821 |
N/A |
|
|
TARS |
Tarsus Pharmaceuticals, Inc. |
15 |
- |
$0.00 |
$170,345,000 |
3,316,032 |
2.61% |
-8,863,000 |
79,483 |
7.487 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
16 |
- |
$32.84 |
$144,487,000 |
4,869,798 |
2.21% |
828,000 |
0 |
9.74 |
N/A |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
17 |
- |
$21.36 |
$141,851,000 |
8,540,117 |
2.17% |
-17,895,000 |
-165,384 |
5.312 |
Biotechnology |
|
|
RCKT |
Rocket Pharmaceuticals |
18 |
- |
$2.59 |
$117,977,000 |
17,687,772 |
1.8% |
-104,358,000 |
0 |
19.099 |
N/A |
|
|
RDNT |
Radnet Inc |
19 |
- |
$55.62 |
$115,230,000 |
2,317,582 |
1.76% |
-22,954,000 |
339,000 |
3.414 |
Specialized Health Se... |
|
|
MASI |
Masimo Corp |
20 |
- |
$169.01 |
$113,837,000 |
683,294 |
1.74% |
889,000 |
0 |
1.241 |
Medical Appliances & ... |
|
|
ZLAB |
Zai Lab Ltd |
21 |
- |
$35.17 |
$113,360,000 |
3,136,680 |
1.73% |
47,646,000 |
627,561 |
3.564 |
N/A |
|
|
CYTK |
Cytokinetics Inc |
22 |
- |
$33.64 |
$109,363,000 |
2,721,158 |
1.67% |
-18,640,000 |
0 |
1.982 |
Biotechnology |
|
|
ESTA |
Establishment Labs Holdings... |
23 |
- |
$43.40 |
$105,436,000 |
2,583,887 |
1.61% |
-12,949,000 |
14,200 |
9.248 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
24 |
- |
$44.26 |
$101,324,000 |
2,712,097 |
1.55% |
-21,534,000 |
0 |
4.637 |
N/A |
|
|
ISRG |
Intuitive Surgical Inc |
25 |
New |
$372.63 |
$100,270,000 |
202,456 |
1.53% |
100,270,000 |
202,456 |
0.057 |
Medical Appliances & ... |
|
|
GMED |
Genomed Inc |
26 |
- |
$60.20 |
$82,350,000 |
1,125,000 |
1.26% |
1,956,000 |
153,000 |
0.975 |
N/A |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
27 |
- |
$36.26 |
$61,825,000 |
1,707,402 |
0.95% |
-20,969,000 |
-260,600 |
1.854 |
Restaurants |
|
|
GHRS |
Gh Research Ord Shs |
28 |
- |
$0.00 |
$60,662,000 |
5,499,769 |
0.93% |
37,372,000 |
2,172,640 |
11.259 |
N/A |
|
|
AGLE |
Aeglea Biotherapeutics, Inc. |
29 |
- |
$0.60 |
$58,441,000 |
3,621,996 |
0.89% |
-25,879,000 |
0 |
5.921 |
N/A |
|
|
QURE |
uniQure B.V. |
30 |
- |
$13.99 |
$45,214,000 |
4,265,428 |
0.69% |
29,256,000 |
3,361,803 |
9.585 |
N/A |
|
|
URGN |
Urogen Pharma Ltd. |
31 |
- |
$13.02 |
$42,413,000 |
3,834,794 |
0.65% |
1,572,000 |
0 |
9.107 |
N/A |
|
|
GEHC |
Ge Healthcare Holding Llc |
32 |
New |
$75.95 |
$41,969,000 |
520,000 |
0.64% |
41,969,000 |
520,000 |
0.114 |
N/A |
|
|
CGON |
CG Oncology, Inc |
33 |
- |
$26.35 |
$41,663,000 |
1,701,216 |
0.64% |
-7,128,000 |
0 |
2.578 |
N/A |
|
|
BBNX |
Beta Bionics, Inc. |
34 |
New |
$13.94 |
$40,390,000 |
3,299,870 |
0.62% |
40,390,000 |
3,299,870 |
7.612 |
N/A |
|
|
OBIO |
Orchestra BioMed Holdings Inc. |
35 |
- |
$2.77 |
$35,122,000 |
8,206,162 |
0.54% |
2,297,000 |
0 |
22.959 |
N/A |
|
|
STOK |
Stoke Therapeutics, Inc. |
36 |
- |
$11.65 |
$34,071,000 |
5,123,525 |
0.52% |
-22,441,000 |
0 |
8.178 |
N/A |
|
|
IMTX |
Immatics N.V |
37 |
- |
$5.54 |
$31,162,000 |
6,909,510 |
0.48% |
-15,341,000 |
368,970 |
6.701 |
N/A |
|
|
TSHA |
Taysha Gene Therapies, Inc. |
38 |
- |
$0.00 |
$26,115,000 |
18,787,866 |
0.4% |
11,111,000 |
10,115,236 |
10.049 |
N/A |
|
|
VSTM |
Verastem, Inc. |
39 |
New |
$4.29 |
$25,600,000 |
4,245,476 |
0.39% |
25,600,000 |
4,245,476 |
9.434 |
Biotechnology |
|
|
XNCR |
Xencor Inc |
40 |
- |
$8.07 |
$25,567,000 |
2,402,883 |
0.39% |
-29,651,000 |
0 |
2.67 |
Biotechnology |
|
|
ARVN |
Arvinas Holding Company, Llc |
41 |
- |
$7.63 |
$23,407,000 |
3,334,308 |
0.36% |
-40,512,000 |
0 |
3.729 |
N/A |
|
|
LENZ |
Lenz Therapeutics |
42 |
- |
$30.05 |
$22,198,000 |
863,389 |
0.34% |
-2,728,000 |
0 |
3.381 |
N/A |
|
|
REPL |
Replimune Group Inc |
43 |
- |
$9.15 |
$20,134,000 |
2,065,010 |
0.31% |
-4,873,000 |
0 |
2.855 |
N/A |
|
|
ORKA |
Oruka Therapeutics, Inc |
44 |
- |
$11.80 |
$19,962,000 |
1,945,649 |
0.31% |
-17,764,000 |
0 |
5.559 |
Diagnostic Substances |
|
|
TEM |
Tempus Ai, Inc. |
45 |
- |
$59.45 |
$19,296,000 |
400,000 |
0.3% |
19,296,000 |
400,000 |
0.25 |
N/A |
|
|
GKOS |
Glaukos Corp |
46 |
- |
$102.52 |
$18,700,000 |
190,000 |
0.29% |
18,700,000 |
190,000 |
0.346 |
N/A |
|
|
DYN |
Dyne Therapeutics, Inc. |
47 |
- |
$8.68 |
$17,683,000 |
1,690,567 |
0.27% |
-105,268,000 |
-3,528,074 |
1.465 |
N/A |
|
|
CRGX |
Cargo Therapeutics, Inc. |
48 |
- |
$0.00 |
$16,788,000 |
4,124,859 |
0.26% |
-42,692,000 |
0 |
0 |
N/A |
|
|
DGX |
Quest Diagnostics Inc |
49 |
New |
$179.33 |
$16,750,000 |
98,997 |
0.26% |
16,750,000 |
98,997 |
0.073 |
Medical Laboratories ... |
|
|
CMPS |
Compass Pathways Plc |
50 |
- |
$0.00 |
$15,839,000 |
5,538,168 |
0.24% |
4,125,000 |
2,439,181 |
15.91 |
N/A |
|
|
NGNE |
Neurogene |
51 |
- |
$3.68 |
$15,793,000 |
1,348,656 |
0.24% |
-15,074,000 |
-1,600 |
3.22 |
N/A |
|
|
RAPT |
Rapt Therapeutics, Inc. |
52 |
- |
$1.03 |
$14,352,000 |
11,764,000 |
0.22% |
-4,235,000 |
0 |
32.581 |
N/A |
|
|
ETNB |
89bio, Inc. |
53 |
- |
$9.73 |
$14,304,000 |
1,967,527 |
0.22% |
-44,174,000 |
-5,510,534 |
1.858 |
N/A |
|
|
CGEM |
Cullinan Oncology Ord Shs |
54 |
- |
$0.00 |
$12,914,000 |
1,705,960 |
0.2% |
-7,865,000 |
0 |
0.392 |
N/A |
|
|
BEAM |
Beam Therapeutics Inc. |
55 |
New |
$17.53 |
$8,567,000 |
438,659 |
0.13% |
8,567,000 |
438,659 |
0.538 |
N/A |
|
|
CRVS |
Corvus Pharmaceuticals, Inc. |
56 |
- |
$3.86 |
$8,521,000 |
2,679,479 |
0.13% |
-5,814,000 |
0 |
4.187 |
N/A |
|
|
PCSC |
Perceptive Capital Solution... |
57 |
- |
$0.00 |
$7,648,000 |
742,500 |
0.12% |
89,000 |
0 |
8.332 |
N/A |
|
|
WVE |
Wave Life Sciences Ltd. |
58 |
- |
$6.52 |
$7,272,000 |
900,000 |
0.11% |
-3,861,000 |
0 |
0.755 |
N/A |
|
|
XGN |
Exagen Inc. |
59 |
- |
$0.00 |
$5,428,000 |
1,511,866 |
0.08% |
-771,000 |
0 |
11.952 |
N/A |
|
|
KMTS |
Kestra Medical Technologies... |
60 |
New |
$15.84 |
$4,984,000 |
200,000 |
0.08% |
4,984,000 |
200,000 |
0.389 |
N/A |
|
|
ALUR |
Allurion Technologies, Inc. |
61 |
- |
$2.45 |
$3,371,000 |
1,050,063 |
0.05% |
2,104,000 |
-1,897,488 |
17.619 |
N/A |
|
|
BIOA |
Bioage Labs, Inc. |
62 |
- |
$4.13 |
$2,957,000 |
786,353 |
0.05% |
-1,596,000 |
0 |
2.195 |
N/A |
|
|
CBLL |
Ceribell, Inc. |
63 |
- |
$18.57 |
$2,882,000 |
150,000 |
0.04% |
-1,000,000 |
0 |
0.419 |
N/A |
|
|
TENX |
Tenax Therapeutics Inc |
64 |
New |
$0.26 |
$2,478,000 |
378,346 |
0.04% |
2,478,000 |
378,346 |
0.846 |
N/A |
|
|
MIST |
Milestone Pharmaceuticals Inc. |
65 |
- |
$0.00 |
$2,005,000 |
2,506,102 |
0.03% |
-3,909,000 |
0 |
3.787 |
N/A |
|
|
CNTA |
Centessa Pharmaceuticals Plc |
66 |
- |
$0.00 |
$719,000 |
50,000 |
0.01% |
-119,000 |
0 |
0.038 |
N/A |
|
|
ADGM |
Adagio Medical Holdings, Inc. |
67 |
- |
$1.35 |
$169,000 |
209,361 |
0% |
-51,000 |
0 |
1.564 |
N/A |
|
|
IMUX |
Immunic Inc |
76 |
Closed |
$0.69 |
$0 |
0 |
0% |
-4,568,000 |
-4,567,717 |
0 |
N/A |
|
|
DNTH |
Dianthus Therapeutics Ord Shs |
69 |
Closed |
$0.70 |
$0 |
0 |
0% |
-14,533,000 |
-666,667 |
0 |
N/A |
|
|
SLRN |
Acelyrin, Inc. |
75 |
Closed |
$2.27 |
$0 |
0 |
0% |
-3,072,000 |
-978,310 |
0 |
N/A |
|
|
ROIV |
Roivant Sciences Ltd. |
81 |
Closed |
$10.94 |
$0 |
0 |
0% |
-17,204,000 |
-1,454,273 |
0 |
N/A |
|
|
GPCR |
Structure Therapeutics Inc. |
68 |
Closed |
$20.51 |
$0 |
0 |
0% |
-3,390,000 |
-125,000 |
0 |
N/A |
|
|
BRKR |
Bruker Corp |
74 |
Closed |
$41.90 |
$0 |
0 |
0% |
-145,443,000 |
-2,481,119 |
0 |
Scientific & Technica... |
|
|
RGNX |
Regenxbio Inc. |
80 |
Closed |
$8.23 |
$0 |
0 |
0% |
-2,706,000 |
-350,000 |
0 |
N/A |
|
|
EPIX |
ESSA Pharma Inc |
73 |
Closed |
$0.00 |
$0 |
0 |
0% |
-1,992,000 |
-1,113,002 |
0 |
Diagnostic Substances |
|
|
SAGE |
Sage Therapeutics, Inc. |
79 |
Closed |
$0.00 |
$0 |
0 |
0% |
-16,303,000 |
-3,002,370 |
0 |
N/A |
|
|
TRML |
Tourmaline Bio |
72 |
Closed |
$0.00 |
$0 |
0 |
0% |
-14,940,000 |
-736,681 |
0 |
N/A |
|
|
PEPG |
Pepgen Inc. |
78 |
Closed |
$1.09 |
$0 |
0 |
0% |
-12,102,000 |
-3,193,097 |
0 |
N/A |
|
|
ARTV |
Artiva Biotherapeutics, Inc. |
71 |
Closed |
$0.00 |
$0 |
0 |
0% |
-1,500,000 |
-148,844 |
0 |
N/A |
|
|
IMVT |
Immunovant Inc |
77 |
Closed |
$0.00 |
$0 |
0 |
0% |
-13,143,000 |
-530,614 |
0 |
N/A |
|
|
IDYA |
Ideaya Biosciences, Inc. |
70 |
Closed |
$0.00 |
$0 |
0 |
0% |
-5,140,000 |
-200,000 |
0 |
N/A |
|
