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| Name: |
Paradigm Biocapital Advisors LP |
| City: |
NEW YORK |
| State: |
NY |
| Zip: |
10017 |
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| Holdings
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39 |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
NUVL |
Nuvalent, Inc. |
1 |
- |
$0.00 |
$313,713,000 |
4,177,830 |
11.04% |
29,802,000 |
319,822 |
6.352 |
N/A |
|
|
ACLX |
Arcellx, Inc. |
2 |
- |
$0.00 |
$265,549,000 |
3,818,095 |
9.35% |
62,495,000 |
159,471 |
7.796 |
N/A |
|
|
ARGX |
Argenx Se |
3 |
- |
$363.73 |
$217,381,000 |
552,120 |
7.65% |
56,620,000 |
129,543 |
1.174 |
N/A |
|
|
IRON |
Disc Medicine, Inc |
4 |
- |
$33.17 |
$148,795,000 |
2,389,902 |
5.24% |
10,988,000 |
4,045 |
9.9 |
N/A |
|
|
CRNX |
Crinetics Pharmaceuticals, ... |
5 |
- |
$50.54 |
$146,270,000 |
3,124,749 |
5.15% |
63,976,000 |
811,830 |
4.252 |
N/A |
|
|
SRPT |
Sarepta Therapeutics Inc |
6 |
New |
$128.30 |
$139,603,000 |
1,078,346 |
4.91% |
139,603,000 |
1,078,346 |
1.281 |
Drug Manufacturers - ... |
|
|
IMCR |
Immunocore Holdings Adr |
7 |
- |
$50.47 |
$116,166,000 |
1,787,176 |
4.09% |
16,837,000 |
333,293 |
4.081 |
N/A |
|
|
LEGN |
Churchill Cap Corp Iii |
8 |
- |
$42.60 |
$111,171,000 |
1,982,006 |
3.91% |
-2,830,000 |
87,362 |
1.534 |
N/A |
|
|
ARVN |
Arvinas Holding Company, Llc |
9 |
- |
$35.95 |
$107,945,000 |
2,614,935 |
3.8% |
69,613,000 |
1,683,632 |
3.801 |
N/A |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
10 |
- |
$0.00 |
$106,974,000 |
2,484,874 |
3.77% |
8,986,000 |
357,474 |
3.301 |
N/A |
|
|
TARS |
Tarsus Pharmaceuticals, Inc. |
11 |
- |
$0.00 |
$104,085,000 |
2,863,406 |
3.66% |
83,329,000 |
1,838,406 |
8.648 |
N/A |
|
|
CERE |
Cerevel Therapeutics Holdin... |
12 |
- |
$41.65 |
$98,511,000 |
2,330,508 |
3.47% |
-303,000 |
0 |
1.491 |
N/A |
|
|
RVMD |
Revolution Medicines, Inc. |
13 |
New |
$39.77 |
$93,950,000 |
2,914,975 |
3.31% |
93,950,000 |
2,914,975 |
1.779 |
N/A |
|
|
OLMA |
Olema Pharmaceuticals, Inc. |
14 |
- |
$0.00 |
$89,469,000 |
7,903,600 |
3.15% |
-21,419,000 |
0 |
14.342 |
N/A |
|
|
VRDN |
Viridian Therapeutics Ors Shs |
15 |
- |
$12.70 |
$88,100,000 |
5,031,420 |
3.1% |
-16,324,000 |
236,932 |
8.022 |
N/A |
|
|
PCVX |
Vaxcyte, Inc. |
16 |
New |
$0.00 |
$84,704,000 |
1,239,995 |
2.98% |
84,704,000 |
1,239,995 |
1.15 |
N/A |
|
|
ALPN |
Alpine Immune Sciences Inc |
17 |
- |
$64.97 |
$84,083,000 |
2,121,163 |
2.96% |
23,534,000 |
-1,055,580 |
3.236 |
N/A |
|
|
BCYC |
Bicycle Therapeutics Ltd |
18 |
- |
$0.00 |
$80,844,000 |
3,246,759 |
2.85% |
13,821,000 |
-460,242 |
8.608 |
N/A |
|
|
ASND |
Ascendis Pharma AS |
19 |
- |
$131.14 |
$76,787,000 |
507,952 |
2.7% |
32,490,000 |
156,252 |
0.786 |
N/A |
|
|
KURA |
Kura Oncology Inc |
20 |
- |
$22.55 |
$66,878,000 |
3,135,387 |
2.35% |
48,719,000 |
1,872,559 |
3.744 |
N/A |
|
|
EWTX |
Edgewise Therapeutics, Inc. |
21 |
New |
$0.00 |
$44,622,000 |
2,446,373 |
1.57% |
44,622,000 |
2,446,373 |
2.651 |
N/A |
|
|
AUTL |
Autolus Therapeutics Plc |
22 |
- |
$3.84 |
$40,997,000 |
6,425,803 |
1.44% |
-40,220,000 |
-6,185,532 |
3.713 |
N/A |
|
|
YMAB |
Y-Mabs Therapeutics Inc |
23 |
New |
$12.85 |
$36,318,000 |
2,233,610 |
1.28% |
36,318,000 |
2,233,610 |
5.583 |
N/A |
|
|
IMTX |
Immatics N.V |
24 |
- |
$10.34 |
$29,627,000 |
2,818,908 |
1.04% |
7,131,000 |
682,569 |
4.481 |
N/A |
|
|
IMVT |
Immunovant Inc |
25 |
New |
$0.00 |
$25,817,000 |
799,054 |
0.91% |
25,817,000 |
799,054 |
0.918 |
N/A |
|
|
CGEM |
Cullinan Oncology Ord Shs |
26 |
New |
$0.00 |
$22,970,000 |
1,348,015 |
0.81% |
22,970,000 |
1,348,015 |
3.097 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
27 |
New |
$47.87 |
$21,929,000 |
330,000 |
0.77% |
21,929,000 |
330,000 |
0.687 |
N/A |
|
|
CMPS |
Compass Pathways Plc |
28 |
- |
$0.00 |
$19,893,000 |
2,390,988 |
0.7% |
66,000 |
125,000 |
6.869 |
N/A |
|
|
VOR |
Vor Biopharma Inc. |
29 |
- |
$0.00 |
$15,304,000 |
6,457,293 |
0.54% |
775,000 |
0 |
9.836 |
N/A |
|
|
ZNTL |
Zentalis Pharmaceuticals, Llc |
30 |
- |
$0.00 |
$14,892,000 |
944,917 |
0.52% |
8,832,000 |
544,917 |
1.113 |
N/A |
|
|
AGIO |
Agios Pharmaceuticals Inc |
31 |
New |
$33.44 |
$11,696,000 |
400,000 |
0.41% |
11,696,000 |
400,000 |
0.579 |
N/A |
|
|
CRBU |
Caribou Biosciences, Inc. |
32 |
- |
$3.11 |
$11,167,000 |
2,172,620 |
0.39% |
-5,587,000 |
-751,231 |
2.457 |
N/A |
|
|
CRGX |
Cargo Therapeutics, Inc. |
33 |
- |
$0.00 |
$3,302,000 |
147,959 |
0.12% |
-4,415,000 |
-185,374 |
0 |
N/A |
|
|
KYTX |
Kyverna Therapeutics |
34 |
New |
$13.33 |
$1,242,000 |
50,000 |
0.04% |
1,242,000 |
50,000 |
0.116 |
N/A |
|
|
MRTX |
Mirati Therapeutics, Inc. |
37 |
Closed |
$58.70 |
$0 |
0 |
0% |
-90,658,000 |
-1,543,116 |
0 |
Biotechnology |
|
|
AMAM |
Ambrx Biopharma Adr Represe... |
36 |
Closed |
$0.00 |
$0 |
0 |
0% |
-61,982,000 |
-4,352,689 |
0 |
N/A |
|
|
AVTE |
Aerovate Therapeutics, Inc. |
35 |
Closed |
$0.00 |
$0 |
0 |
0% |
-3,241,000 |
-143,235 |
0 |
N/A |
|
|
ZLAB |
Zai Lab Ltd |
39 |
Closed |
$20.16 |
$0 |
0 |
0% |
-29,838,000 |
-1,091,779 |
0 |
N/A |
|
|
TGTX |
TG Therapeutics Inc |
38 |
Closed |
$17.70 |
$0 |
0 |
0% |
-37,088,000 |
-2,171,419 |
0 |
Drug Manufacturers - ... |
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