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| Name: |
SPHERA FUNDS MANAGEMENT LTD. |
| City: |
Tel Aviv |
| State: |
L3 |
| Zip: |
64739 |
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Menu
 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
TEVA |
Teva Pharmaceutical Industr... |
1 |
- |
$12.78 |
$25,777,000 |
2,469,100 |
4.79% |
19,657,000 |
1,869,100 |
0.225 |
Drug Manufacturers - ... |
|
|
SNY |
Sanofi Aventis (ADR) |
2 |
- |
$45.39 |
$24,841,000 |
499,515 |
4.61% |
-1,953,000 |
0 |
0.02 |
Drug Manufacturers - ... |
|
|
CYTK |
Cytokinetics Inc |
3 |
- |
$67.00 |
$18,687,000 |
223,820 |
3.47% |
11,795,000 |
-10,113 |
0.198 |
Biotechnology |
|
|
NVMI |
Nova Measuring Instruments,... |
4 |
- |
$170.00 |
$18,135,000 |
132,000 |
3.37% |
18,135,000 |
132,000 |
0.467 |
Semiconductor Equipme... |
|
|
SNDX |
Syndax Pharmaceuticals Inc |
5 |
- |
$20.49 |
$16,704,000 |
772,964 |
3.1% |
5,479,000 |
-97 |
1.007 |
N/A |
|
|
TSEM |
Tower Semiconductor Ltd (USA) |
6 |
- |
$31.15 |
$16,124,000 |
528,300 |
2.99% |
4,591,000 |
58,726 |
0.493 |
Semiconductor - Integ... |
|
|
NICE |
NICE Systems Ltd (ADR) |
7 |
- |
$230.95 |
$13,510,000 |
67,718 |
2.51% |
7,138,000 |
30,236 |
0.108 |
Computer Peripherals |
|
|
MRK |
Merck & Co Inc |
8 |
- |
$125.23 |
$13,475,000 |
123,600 |
2.5% |
750,000 |
0 |
0.005 |
Drug Manufacturers - ... |
|
|
CLDX |
Celldex Therapeutics Inc |
9 |
- |
$38.53 |
$12,518,000 |
315,644 |
2.32% |
7,564,000 |
135,644 |
0.603 |
Diagnostic Substances |
|
|
JNJ |
Johnson & Johnson |
10 |
- |
$145.74 |
$12,513,000 |
79,831 |
2.32% |
-2,257,000 |
-15,000 |
0.003 |
Drug Manufacturers - ... |
|
|
FB |
Meta Platforms Inc |
11 |
- |
$501.80 |
$12,142,000 |
34,303 |
2.25% |
7,573,000 |
19,083 |
0.001 |
Internet Service Prov... |
|
|
AZN |
AstraZeneca Plc (ADR) |
12 |
- |
$68.36 |
$12,127,000 |
180,060 |
2.25% |
-7,177,000 |
-105,000 |
0.007 |
Drug Manufacturers - ... |
|
|
BIIB |
Biogen Idec Inc |
13 |
- |
$190.52 |
$11,993,000 |
46,346 |
2.23% |
5,350,000 |
20,500 |
0.03 |
Biotechnology |
|
|
BBIO |
Bridgebio Pharma, Inc. |
14 |
- |
$24.95 |
$11,390,000 |
282,146 |
2.11% |
2,278,000 |
-63,391 |
0.177 |
N/A |
|
|
GLBE |
Global E Online Ord Shs |
15 |
New |
$33.69 |
$10,692,000 |
269,794 |
1.99% |
10,692,000 |
269,794 |
0.19 |
N/A |
|
|
FUSN |
Fusion Pharmaceuticals Inc. |
16 |
- |
$21.25 |
$10,433,000 |
1,085,639 |
1.94% |
6,912,000 |
-268,619 |
2.269 |
N/A |
|
|
KURA |
Kura Oncology Inc |
17 |
- |
$17.68 |
$10,113,000 |
703,287 |
1.88% |
3,699,000 |
0 |
0.923 |
N/A |
|
|
NVO |
Novo Nordisk A/S (ADR) |
18 |
- |
$122.75 |
$9,629,000 |
93,080 |
1.79% |
1,164,000 |
0 |
0.005 |
Drug Manufacturers - ... |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
19 |
- |
$43.38 |
$9,614,000 |
201,044 |
1.78% |
376,000 |
-58,091 |
0.295 |
Restaurants |
|
|
MSFT |
Microsoft Corp |
20 |
- |
$404.27 |
$8,968,000 |
23,848 |
1.66% |
-1,907,000 |
-10,594 |
0 |
Application Software |
|
|
ATXS |
Astria Therapeutics, Inc |
21 |
- |
$10.54 |
$8,841,000 |
1,151,145 |
1.64% |
4,510,000 |
570,546 |
4.641 |
N/A |
|
|
INBX |
Inhibrx, Inc. |
22 |
- |
$0.00 |
$8,609,000 |
226,551 |
1.6% |
3,905,000 |
-29,820 |
0.601 |
N/A |
|
|
AMZN |
Amazon.com Inc |
23 |
- |
$179.22 |
$8,459,000 |
55,676 |
1.57% |
-3,656,000 |
-39,624 |
0.001 |
Internet Software & S... |
|
|
LLY |
Eli Lilly & Co |
24 |
- |
$745.95 |
$8,272,000 |
14,190 |
1.54% |
650,000 |
0 |
0.001 |
Drug Manufacturers - ... |
|
|
DAWN |
Day One Biopharmaceuticals,... |
25 |
- |
$0.00 |
$7,490,000 |
513,000 |
1.39% |
987,000 |
-17,000 |
0.828 |
N/A |
|
|
TBLA |
Taboolacom Ord Shs |
26 |
New |
$0.00 |
$7,469,000 |
1,724,948 |
1.39% |
7,469,000 |
1,724,948 |
0.818 |
N/A |
|
|
AMD |
Advanced Micro Devices Inc |
27 |
- |
$155.08 |
$7,428,000 |
50,387 |
1.38% |
2,460,000 |
2,067 |
0.004 |
Semiconductor- Broad... |
|
|
PRAX |
Praxis Precision Medicines,... |
28 |
- |
$0.00 |
$7,330,000 |
328,986 |
1.36% |
-964,000 |
-4,521,331 |
0.628 |
N/A |
|
|
ABBV |
Abbvie Inc. |
29 |
- |
$164.66 |
$7,129,000 |
46,000 |
1.32% |
272,000 |
0 |
0.003 |
Drug Manufacturers - ... |
|
|
WIX |
WIX.COM Ltd |
30 |
New |
$121.77 |
$7,071,000 |
57,477 |
1.31% |
7,071,000 |
57,477 |
0.103 |
N/A |
|
|
ALNY |
Alnylam Pharmaceuticals Inc |
31 |
- |
$145.16 |
$6,935,000 |
36,230 |
1.29% |
542,000 |
129 |
0.029 |
Biotechnology |
|
|
PHVS |
Pharvaris N V Ord Shs |
32 |
New |
$0.00 |
$6,872,000 |
245,000 |
1.28% |
6,872,000 |
245,000 |
0.74 |
N/A |
|
|
INZY |
Inozyme Pharma, Inc. |
33 |
- |
$0.00 |
$6,658,000 |
1,562,907 |
1.24% |
1,471,000 |
328,000 |
2.531 |
N/A |
|
|
IMTX |
Immatics N.V |
34 |
- |
$10.26 |
$6,540,000 |
621,111 |
1.21% |
-607,000 |
3,938 |
0.987 |
N/A |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
35 |
- |
$222.26 |
$6,425,000 |
27,767 |
1.19% |
-1,004,000 |
-23,100 |
0.167 |
Diagnostic Substances |
|
|
MLYS |
Mineralys Therapeutics, Inc. |
36 |
- |
$0.00 |
$6,395,000 |
743,591 |
1.19% |
2,064,000 |
288,191 |
1.82 |
N/A |
|
|
MRUS |
Merus Nv |
37 |
- |
$40.47 |
$6,334,000 |
230,333 |
1.18% |
360,000 |
-23,000 |
0.54 |
N/A |
|
|
SWTX |
Springworks Therapeutics, Inc. |
38 |
- |
$0.00 |
$6,215,000 |
170,270 |
1.15% |
-1,181,000 |
-149,641 |
0.245 |
N/A |
|
|
NVS |
Novartis AG (ADR) |
39 |
- |
$92.57 |
$6,058,000 |
60,000 |
1.12% |
-54,000 |
0 |
0.002 |
Drug Manufacturers - ... |
|
|
S |
Sentinelone, Inc. |
40 |
New |
$20.61 |
$5,856,000 |
213,418 |
1.09% |
5,856,000 |
213,418 |
0.108 |
N/A |
|
|
RCKT |
Rocket Pharmaceuticals |
41 |
- |
$23.48 |
$5,718,000 |
190,783 |
1.06% |
1,435,000 |
-18,257 |
0.242 |
N/A |
|
|
JSPR |
Jasper Therapeutics Ord Shs |
42 |
- |
$15.12 |
$5,626,000 |
713,063 |
1.04% |
1,645,000 |
-4,974,071 |
0.702 |
N/A |
|
|
INCY |
Incyte Corp |
43 |
New |
$52.82 |
$5,623,000 |
89,556 |
1.04% |
5,623,000 |
89,556 |
0.041 |
Biotechnology |
|
|
GRCL |
Gracell Biotechnologies Adr... |
44 |
- |
$0.00 |
$5,049,000 |
502,936 |
0.94% |
638,000 |
-1,028,561 |
0.748 |
N/A |
|
|
PANW |
Palo Alto Networks Inc |
45 |
- |
$281.14 |
$4,891,000 |
16,585 |
0.91% |
-1,851,000 |
-12,174 |
0.006 |
Networking & Communic... |
|
|
ENPH |
Enphase Energy, Inc. |
46 |
New |
$109.17 |
$4,598,000 |
34,800 |
0.85% |
4,598,000 |
34,800 |
0.028 |
Semiconductor Equipme... |
|
|
ETNB |
89bio, Inc. |
47 |
- |
$8.88 |
$4,565,000 |
408,674 |
0.85% |
-365,000 |
89,373 |
0.549 |
N/A |
|
|
SEDG |
Solaredge Technologies Inc |
48 |
New |
$57.39 |
$4,493,000 |
48,000 |
0.83% |
4,493,000 |
48,000 |
0.094 |
N/A |
|
|
ALPN |
Alpine Immune Sciences Inc |
49 |
- |
$64.43 |
$4,476,000 |
234,841 |
0.83% |
2,415,000 |
54,841 |
0.512 |
N/A |
|
|
ARWR |
Arrowhead Pharmaceuticals Inc |
50 |
New |
$22.61 |
$4,434,000 |
144,899 |
0.82% |
4,434,000 |
144,899 |
0.142 |
Business Services |
|
|
VTGN |
Vistagen Therapeutics Inc |
51 |
- |
$4.70 |
$4,156,000 |
808,550 |
0.77% |
3,632,000 |
708,550 |
8.379 |
Biotechnology |
|
|
FROG |
Jfrog Ltd |
52 |
New |
$37.94 |
$3,804,000 |
109,905 |
0.71% |
3,804,000 |
109,905 |
0.124 |
N/A |
|
|
PTCT |
PTC Therapeutics, Inc. |
53 |
- |
$24.69 |
$3,763,000 |
136,525 |
0.7% |
-1,133,000 |
-81,934 |
0.167 |
Biotechnology |
|
|
UPWK |
Upwork Inc |
54 |
New |
$11.23 |
$3,759,000 |
252,784 |
0.7% |
3,759,000 |
252,784 |
0.21 |
N/A |
|
|
GSK |
GlaxoSmithKline Plc (ADR) |
55 |
- |
$40.41 |
$3,706,000 |
100,000 |
0.69% |
81,000 |
0 |
0.005 |
Drug Manufacturers - ... |
|
|
PLRX |
Pliant Therapeutics, Inc. |
56 |
- |
$0.00 |
$3,505,000 |
193,554 |
0.65% |
798,000 |
37,420 |
0.308 |
N/A |
|
|
ENLT |
Enlight Renewable Energy Or... |
57 |
- |
$16.28 |
$3,240,000 |
169,280 |
0.6% |
3,240,000 |
169,280 |
0.144 |
N/A |
|
|
AMLX |
Amylyx Pharmaceuticals, Inc. |
58 |
- |
$0.00 |
$2,703,000 |
183,650 |
0.5% |
-843,000 |
-10,000 |
0.317 |
N/A |
|
|
PFE |
Pfizer Inc |
59 |
- |
$25.39 |
$2,591,000 |
90,000 |
0.48% |
-394,000 |
0 |
0.002 |
Drug Manufacturers - ... |
|
|
HOWL |
Werewolf Therapeutics, Inc. |
60 |
- |
$0.00 |
$2,419,000 |
626,810 |
0.45% |
1,078,000 |
0 |
2.274 |
N/A |
|
|
PMN |
Promis Neurosciences Ord Shs |
61 |
- |
$2.00 |
$2,109,000 |
1,834,042 |
0.39% |
-1,577,000 |
0 |
21.376 |
N/A |
|
|
ICL |
Icl Group Inc |
62 |
- |
$3.37 |
$2,104,000 |
420,000 |
0.39% |
-505,000 |
-50,000 |
0.033 |
N/A |
|
|
AVGO |
Broadcom Limited |
63 |
New |
$1,258.99 |
$2,009,000 |
1,800 |
0.37% |
2,009,000 |
1,800 |
0 |
Semiconductor- Broad... |
|
|
KZR |
Kezar Life Sciences, Inc. |
64 |
- |
$0.79 |
$1,944,000 |
2,051,676 |
0.36% |
-497,000 |
0 |
3.001 |
N/A |
|
|
VIGL |
Vigil Neuroscience, Inc. |
65 |
New |
$0.00 |
$1,809,000 |
535,120 |
0.34% |
1,809,000 |
535,120 |
1.893 |
N/A |
|
|
RIGL |
Rigel Pharmaceuticals Inc |
66 |
- |
$1.22 |
$1,781,000 |
1,228,126 |
0.33% |
455,000 |
0 |
0.727 |
Drug Manufacturers - ... |
|
|
CRGX |
Cargo Therapeutics, Inc. |
67 |
New |
$0.00 |
$1,736,000 |
75,000 |
0.32% |
1,736,000 |
75,000 |
0 |
N/A |
|
|
GILD |
Gilead Sciences Inc |
68 |
- |
$66.16 |
$1,620,000 |
20,000 |
0.3% |
-1,378,000 |
-20,000 |
0.002 |
Biotechnology |
|
|
COGT |
Cogent Biosciences, Inc. |
69 |
- |
$6.61 |
$1,524,000 |
259,201 |
0.28% |
-2,571,000 |
-160,799 |
0.328 |
N/A |
|
|
CGEN |
Compugen Ltd (USA) |
70 |
- |
$1.88 |
$1,523,000 |
769,239 |
0.28% |
296,000 |
-550,000 |
0.928 |
Biotechnology |
|
|
GOSS |
Gossamer Bio Inc |
71 |
- |
$0.81 |
$1,221,000 |
1,338,090 |
0.23% |
-388,000 |
-594,478 |
1.416 |
N/A |
|
|
SRPT |
Sarepta Therapeutics Inc |
72 |
- |
$116.55 |
$1,205,000 |
12,500 |
0.22% |
-4,856,000 |
-37,500 |
0.015 |
Drug Manufacturers - ... |
|
|
FIVN |
Five9, Inc. |
73 |
New |
$57.42 |
$1,180,000 |
15,000 |
0.22% |
1,180,000 |
15,000 |
0.02 |
N/A |
|
|
ORIC |
Oric Pharmaceuticals, Inc. |
74 |
New |
$0.00 |
$1,167,000 |
126,800 |
0.22% |
1,167,000 |
126,800 |
0.322 |
N/A |
|
|
RZLT |
Rezolute, Inc |
75 |
- |
$3.30 |
$989,000 |
996,710 |
0.18% |
-327,000 |
0 |
2.968 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
76 |
- |
$48.35 |
$838,000 |
30,000 |
0.16% |
199,000 |
0 |
0.081 |
N/A |
|
|
PRME |
Prime Medicine, Inc. |
77 |
New |
$4.59 |
$655,000 |
73,980 |
0.12% |
655,000 |
73,980 |
0.076 |
N/A |
|
|
SELB |
Selecta Biosciences Inc |
78 |
- |
$0.50 |
$519,000 |
752,137 |
0.1% |
-278,000 |
0 |
0.696 |
N/A |
|
|
MDWD |
MediWound Ltd. |
79 |
- |
$16.99 |
$498,000 |
48,980 |
0.09% |
-657,000 |
-59,553 |
0.18 |
N/A |
|
|
ELEV |
Elevation Oncology, Inc. |
80 |
- |
$4.01 |
$483,000 |
900,000 |
0.09% |
-113,000 |
0 |
3.944 |
N/A |
|
|
VTYX |
Ventyx Biosciences, Inc. |
81 |
New |
$4.35 |
$445,000 |
180,000 |
0.08% |
445,000 |
180,000 |
0.358 |
N/A |
|
|
MORF |
Morphic Holding, Inc. |
82 |
- |
$27.51 |
$432,000 |
14,952 |
0.08% |
-1,630,000 |
-75,048 |
0.039 |
N/A |
|
|
IMTXW |
Immatics N.V - Warrants |
83 |
- |
$0.00 |
$292,000 |
100,000 |
0.05% |
-62,000 |
0 |
1.111 |
N/A |
|
|
GLUE |
Monte Rosa Therapeutics, Inc. |
84 |
New |
$0.00 |
$274,000 |
48,511 |
0.05% |
274,000 |
48,511 |
0.109 |
N/A |
|
|
REPL |
Replimune Group Inc |
85 |
- |
$6.97 |
$136,000 |
16,096 |
0.03% |
-3,030,000 |
-168,920 |
0.028 |
N/A |
|
|
FRLN |
Freeline Therapeutics Hldgs |
86 |
New |
$0.00 |
$105,000 |
16,445 |
0.02% |
105,000 |
16,445 |
0.026 |
N/A |
|
|
ARBE |
Arbe Robotics Ltd |
87 |
- |
$1.90 |
$94,000 |
43,165 |
0.02% |
94,000 |
43,165 |
0.48 |
N/A |
|
|
ISR |
IsoRay, Inc. |
88 |
New |
$1.47 |
$10,000 |
25,671 |
0% |
10,000 |
25,671 |
0.047 |
Medical Instruments &... |
|
|
VERA |
Vera Therapeutics, Inc. |
95 |
Closed |
$0.00 |
$0 |
0 |
0% |
-1,440,000 |
-105,000 |
0 |
N/A |
|
|
QURE |
uniQure B.V. |
94 |
Closed |
$4.71 |
$0 |
0 |
0% |
-998,000 |
-148,734 |
0 |
N/A |
|
|
PNT |
Point Biopharma Global Ord Shs |
96 |
Closed |
$0.00 |
$0 |
0 |
0% |
-6,354,000 |
-952,642 |
0 |
N/A |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
93 |
Closed |
$0.00 |
$0 |
0 |
0% |
-1,331,000 |
-38,959 |
0 |
N/A |
|
|
CRWD |
Crowdstrike Holdings, Inc. |
90 |
Closed |
$294.10 |
$0 |
0 |
0% |
-2,511,000 |
-15,000 |
0 |
N/A |
|
|
CALT |
Calliditas Therapeutics Ab |
92 |
Closed |
$0.00 |
$0 |
0 |
0% |
-217,000 |
-11,863 |
0 |
N/A |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
89 |
Closed |
$0.00 |
$0 |
0 |
0% |
-3,611,000 |
-114,284 |
0 |
N/A |
|
|
IRON |
Disc Medicine, Inc |
97 |
Closed |
$30.02 |
$0 |
0 |
0% |
-5,233,000 |
-111,398 |
0 |
N/A |
|
|
XBI |
streetTRACKS Series Trust S... |
91 |
Closed |
$83.48 |
$0 |
0 |
0% |
-3,651,000 |
-50,000 |
0 |
Closed - End Fund - E... |
|
