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| Name: |
INTERNATIONAL BIOTECHNOLOGY TRUST PLC |
| City: |
LONDON |
| State: |
X0 |
| Zip: |
NW1 6AA |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
AMGN |
Amgen Inc |
1 |
- |
$269.98 |
$21,297,000 |
79,246 |
7.17% |
-4,728,000 |
-38,000 |
0.014 |
Biotechnology |
|
|
INCY |
Incyte Corp |
2 |
- |
$51.68 |
$20,704,000 |
358,454 |
6.97% |
-1,599,000 |
0 |
0.164 |
Biotechnology |
|
|
GILD |
Gilead Sciences Inc |
3 |
- |
$65.42 |
$17,507,000 |
233,584 |
5.9% |
6,370,000 |
89,000 |
0.019 |
Biotechnology |
|
|
ITCI |
Intra Cellular Therapies Inc |
4 |
- |
$73.26 |
$16,548,000 |
317,856 |
5.57% |
5,365,000 |
141,000 |
0.337 |
N/A |
|
|
BMRN |
Biomarin Pharmaceutical Inc |
5 |
- |
$88.63 |
$13,595,000 |
153,656 |
4.58% |
8,512,000 |
95,000 |
0.082 |
Drug Manufacturers - ... |
|
|
SUPN |
Supernus Pharmaceuticals Inc |
6 |
- |
$30.07 |
$11,754,000 |
426,500 |
3.96% |
-3,982,000 |
-97,000 |
0.728 |
Drugs - Generic |
|
|
VERA |
Vera Therapeutics, Inc. |
7 |
- |
$0.00 |
$10,382,000 |
758,355 |
3.5% |
-5,261,000 |
-216,872 |
1.791 |
N/A |
|
|
BIIB |
Biogen Idec Inc |
8 |
- |
$208.90 |
$10,334,000 |
40,200 |
3.48% |
7,201,000 |
29,200 |
0.026 |
Biotechnology |
|
|
HRMY |
Harmony Biosciences Holding... |
9 |
- |
$0.00 |
$10,306,000 |
314,500 |
3.47% |
-9,764,000 |
-256,000 |
0.494 |
N/A |
|
|
MRTX |
Mirati Therapeutics, Inc. |
10 |
- |
$58.70 |
$9,405,000 |
216,000 |
3.17% |
11,000 |
-44,000 |
0.323 |
Biotechnology |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
11 |
- |
$44.24 |
$8,914,000 |
250,052 |
3% |
5,223,000 |
170,000 |
0.367 |
Restaurants |
|
|
QURE |
uniQure B.V. |
12 |
- |
$4.53 |
$8,330,000 |
1,241,500 |
2.81% |
8,152,000 |
1,226,000 |
2.79 |
N/A |
|
|
AUPH |
Aurinia Pharmaceuticals Inc |
13 |
- |
$4.91 |
$8,075,000 |
1,040,530 |
2.72% |
2,523,000 |
467,000 |
0.822 |
N/A |
|
|
UTHR |
United Therapeutics Corp |
14 |
- |
$233.85 |
$7,658,000 |
33,959 |
2.58% |
-3,989,000 |
-18,800 |
0.072 |
Drug Manufacturers - ... |
|
|
VRTX |
Vertex Pharmaceuticals Inc |
15 |
- |
$397.48 |
$7,303,000 |
21,000 |
2.46% |
-84,000 |
0 |
0.008 |
Drug Manufacturers - ... |
|
|
REGN |
Regeneron Pharmaceuticals Inc |
16 |
- |
$883.20 |
$7,278,000 |
8,847 |
2.45% |
-12,122,000 |
-18,153 |
0.008 |
Biotechnology |
|
|
ILMN |
Illumina Inc |
17 |
- |
$122.28 |
$6,933,000 |
50,500 |
2.34% |
-2,530,000 |
0 |
0.035 |
Scientific & Technica... |
|
|
ALNY |
Alnylam Pharmaceuticals Inc |
18 |
- |
$143.31 |
$6,517,000 |
36,800 |
2.2% |
-8,982,000 |
-44,800 |
0.03 |
Biotechnology |
|
|
AMLX |
Amylyx Pharmaceuticals, Inc. |
19 |
- |
$0.00 |
$5,399,000 |
295,000 |
1.82% |
4,860,000 |
270,000 |
0.51 |
N/A |
|
|
KRYS |
Krystal Biotech Inc |
20 |
- |
$156.88 |
$5,345,000 |
46,092 |
1.8% |
-44,000 |
147 |
0.185 |
N/A |
|
|
KRTX |
Karuna Therapeutics, Inc. |
21 |
- |
$0.00 |
$5,157,000 |
30,500 |
1.74% |
-410,000 |
4,800 |
0.076 |
N/A |
|
|
AXSM |
Axsome Therapeutics, Inc. |
22 |
- |
$71.71 |
$4,071,000 |
58,300 |
1.37% |
-115,000 |
0 |
0.156 |
N/A |
|
|
ERAS |
Erasca, Inc. |
23 |
- |
$1.89 |
$3,794,000 |
1,926,000 |
1.28% |
-128,000 |
500,000 |
1.592 |
N/A |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
24 |
- |
$16.71 |
$3,740,000 |
179,702 |
1.26% |
124,000 |
28,702 |
0.112 |
Biotechnology |
|
|
RVNC |
Revance Therapeutics, Inc. |
25 |
- |
$3.40 |
$3,309,000 |
288,726 |
1.11% |
-3,990,000 |
0 |
0.351 |
N/A |
|
|
NBIX |
Neurocrine Biosciences Inc |
26 |
- |
$135.99 |
$3,247,000 |
28,877 |
1.09% |
-3,243,000 |
-40,000 |
0.031 |
Biotechnology |
|
|
SRPT |
Sarepta Therapeutics Inc |
27 |
- |
$128.77 |
$3,235,000 |
26,700 |
1.09% |
1,082,000 |
7,900 |
0.032 |
Drug Manufacturers - ... |
|
|
RCKT |
Rocket Pharmaceuticals |
28 |
- |
$21.98 |
$3,193,000 |
156,000 |
1.08% |
100,000 |
0 |
0.198 |
N/A |
|
|
DNLI |
Denali Therapeutics Inc. |
29 |
- |
$15.43 |
$3,172,000 |
154,000 |
1.07% |
-2,366,000 |
-34,000 |
0.128 |
N/A |
|
|
AZN |
AstraZeneca Plc (ADR) |
30 |
- |
$75.17 |
$3,149,000 |
46,500 |
1.06% |
3,149,000 |
46,500 |
0.002 |
Drug Manufacturers - ... |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
31 |
- |
$0.00 |
$3,122,000 |
91,500 |
1.05% |
2,140,000 |
66,000 |
0.146 |
N/A |
|
|
CRSP |
Crispr Therapeutics Ag |
32 |
- |
$53.91 |
$2,859,000 |
63,000 |
0.96% |
2,859,000 |
63,000 |
0.089 |
N/A |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
33 |
- |
$193.33 |
$2,669,000 |
18,300 |
0.9% |
-1,558,000 |
0 |
0.11 |
Diagnostic Substances |
|
|
LEGN |
Churchill Cap Corp Iii |
34 |
- |
$45.30 |
$2,551,000 |
38,000 |
0.86% |
-72,000 |
0 |
0.029 |
N/A |
|
|
HALO |
Halozyme Therapeutics Inc |
35 |
- |
$38.57 |
$2,376,000 |
62,200 |
0.8% |
-1,068,000 |
-33,300 |
0.045 |
Biotechnology |
|
|
MRNS |
Marinus Pharmaceuticals Inc |
36 |
- |
$1.41 |
$2,337,000 |
290,000 |
0.79% |
1,360,000 |
200,000 |
0.584 |
N/A |
|
|
BGNE |
Beigene Ltd |
37 |
- |
$153.58 |
$2,282,000 |
12,700 |
0.77% |
734,000 |
4,000 |
0.014 |
N/A |
|
|
JAZZ |
Jazz Pharmaceuticals Inc |
38 |
- |
$109.27 |
$2,225,000 |
17,200 |
0.75% |
93,000 |
0 |
0.028 |
Biotechnology |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
39 |
- |
$0.00 |
$2,129,000 |
67,500 |
0.72% |
386,000 |
0 |
0.183 |
N/A |
|
|
IOVA |
Iovance Biotherapeutics Inc |
40 |
- |
$11.64 |
$2,025,000 |
445,000 |
0.68% |
1,568,000 |
380,000 |
0.208 |
N/A |
|
|
IONS |
Ionis Pharmaceuticals Inc |
41 |
- |
$41.59 |
$1,949,000 |
43,000 |
0.66% |
185,000 |
0 |
0.031 |
Drug Manufacturers - ... |
|
|
ZLAB |
Zai Lab Ltd |
42 |
- |
$15.91 |
$1,918,000 |
78,958 |
0.65% |
-272,000 |
0 |
0.09 |
N/A |
|
|
GMXAY |
GENMAB AS |
43 |
- |
$28.15 |
$1,562,000 |
44,300 |
0.53% |
1,562,000 |
44,300 |
0.072 |
N/A |
|
|
CLDX |
Celldex Therapeutics Inc |
44 |
- |
$36.30 |
$1,322,000 |
48,099 |
0.45% |
-308,000 |
0 |
0.092 |
Diagnostic Substances |
|
|
COGT |
Cogent Biosciences, Inc. |
45 |
New |
$6.02 |
$1,314,000 |
135,000 |
0.44% |
1,314,000 |
135,000 |
0.171 |
N/A |
|
|
DYN |
Dyne Therapeutics, Inc. |
46 |
- |
$24.73 |
$1,231,000 |
137,751 |
0.41% |
-2,152,000 |
-163,000 |
0.242 |
N/A |
|
|
NVCR |
Novocure Ltd |
47 |
- |
$12.64 |
$1,194,000 |
74,000 |
0.4% |
-134,000 |
42,000 |
0.073 |
N/A |
|
|
FOLD |
Amicus Therapeutics Inc |
48 |
New |
$10.61 |
$1,093,000 |
90,000 |
0.37% |
1,093,000 |
90,000 |
0.027 |
Biotechnology |
|
|
CYTK |
Cytokinetics Inc |
49 |
- |
$65.34 |
$1,090,000 |
37,000 |
0.37% |
-116,000 |
0 |
0.033 |
Biotechnology |
|
|
GH |
Guardant Health, Inc. |
50 |
- |
$0.00 |
$1,081,000 |
36,500 |
0.36% |
-225,000 |
0 |
0.037 |
N/A |
|
|
INSM |
Insmed Inc |
51 |
- |
$24.80 |
$1,012,000 |
40,100 |
0.34% |
167,000 |
0 |
0.026 |
Biotechnology |
|
|
BPMC |
Blueprint Medicines Corp |
52 |
New |
$93.00 |
$1,002,000 |
20,000 |
0.34% |
1,002,000 |
20,000 |
0.03 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
53 |
- |
$0.00 |
$935,000 |
18,489 |
0.31% |
-2,727,000 |
-60,000 |
0.037 |
N/A |
|
|
KZR |
Kezar Life Sciences, Inc. |
54 |
New |
$0.80 |
$831,000 |
703,825 |
0.28% |
831,000 |
703,825 |
1.029 |
N/A |
|
|
NTLA |
Intellia Therapeutics, Inc. |
55 |
- |
$20.76 |
$758,000 |
24,000 |
0.26% |
-220,000 |
0 |
0.027 |
N/A |
|
|
PRTA |
Prothena Corp Plc |
56 |
New |
$20.87 |
$723,000 |
15,000 |
0.24% |
723,000 |
15,000 |
0.029 |
N/A |
|
|
AGIO |
Agios Pharmaceuticals Inc |
57 |
- |
$31.49 |
$594,000 |
24,000 |
0.2% |
-86,000 |
0 |
0.035 |
N/A |
|
|
BEAM |
Beam Therapeutics Inc. |
58 |
- |
$21.38 |
$565,000 |
23,500 |
0.19% |
-185,000 |
0 |
0.037 |
N/A |
|
|
VTYX |
Ventyx Biosciences, Inc. |
59 |
- |
$3.93 |
$521,000 |
15,000 |
0.18% |
30,000 |
0 |
0.03 |
N/A |
|
|
VIR |
Vir Biotechnology, Inc. |
60 |
New |
$0.00 |
$440,000 |
47,000 |
0.15% |
440,000 |
47,000 |
0.037 |
N/A |
|
|
IMAB |
I Mab Adr |
61 |
- |
$1.80 |
$410,000 |
310,499 |
0.14% |
-515,000 |
0 |
0.44 |
N/A |
|
|
PTCT |
PTC Therapeutics, Inc. |
62 |
- |
$28.57 |
$381,000 |
17,000 |
0.13% |
-311,000 |
0 |
0.021 |
Biotechnology |
|
|
ARVN |
Arvinas Holding Company, Llc |
63 |
- |
$32.37 |
$334,000 |
17,000 |
0.11% |
-87,000 |
0 |
0.032 |
N/A |
|
|
PTGX |
Protagonist Therapeutics, Inc |
64 |
- |
$25.15 |
$332,000 |
19,900 |
0.11% |
-217,000 |
0 |
0.035 |
N/A |
|
|
RLMD |
Relmada Therapeutics, Inc. |
65 |
- |
$3.83 |
$30,000 |
10,000 |
0.01% |
5,000 |
0 |
0.036 |
N/A |
|
|
APLS |
Apellis Pharmaceuticals Inc |
66 |
Closed |
$49.86 |
$0 |
0 |
0% |
-11,810,000 |
-129,700 |
0 |
N/A |
|
|
HZNP |
Horizon Pharma, Inc. |
69 |
Closed |
$28.30 |
$0 |
0 |
0% |
-6,891,000 |
-67,000 |
0 |
Drug Manufacturers - ... |
|
|
HCM |
Hutchison China MediTech Ltd |
70 |
Closed |
$18.16 |
$0 |
0 |
0% |
-816,000 |
-68,000 |
0 |
Mortgage Investment |
|
|
TVTX |
Travere Therapeutics, Inc |
68 |
Closed |
$5.26 |
$0 |
0 |
0% |
-6,770,000 |
-441,019 |
0 |
N/A |
|
|
SAGE |
Sage Therapeutics, Inc. |
67 |
Closed |
$0.00 |
$0 |
0 |
0% |
-939,000 |
-20,000 |
0 |
N/A |
|
