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| Exchange: |
Nasdaq National Market |
| Security
Type: |
Common |
| Shares
Out: |
130,390,000 |
| Market
Cap: |
58.53(B) |
| Last
Volume: |
713,356 |
Avg
Vol: |
761,723 |
| 52
Week Range: |
$224.32 - $442.73 |
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| Level
I Sector: |
Health Care |
| Level
II Sector: |
Drugs |
| Level
III Sector: |
Biotechnology |
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Member Indexes:
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NASDAQ BIOTECHNOLOGY |
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NASDAQ COMPOSITE |
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NASDAQ NNM COMPOSITE |
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Rankings:
|
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| Insider 3 Months : - |
| Insider 6 Months : - |
| Insider 3/6 Months : - |
|
| Guru Rank Number : 529 |
| Guru Rank Value : 3.6 |
| Guru Occurances : 2 |
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Company Profile Alnylam Pharmaceuticals is a commercial-stage biopharmaceutical company developing therapeutics based on RNA interference. Co. has four RNAi-based medicines, ONPATTRO® (patisiran), GIVLAARI® (givosiran), OXLUMO™ (lumasiran) and Leqvio® (inclisiran). ONPATTRO is approved for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults. GIVLAARI is approved for the treatment of adults with acute hepatic porphyria. Co. has approval for OXLUMO for the treatment of hyperoxaluria type 1 (PH1) in all age groups. Leqvio (inclisiran) is being developed for the treatment of adults with hypercholesterolemia or mixed dyslipidemia.
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D/I:
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D
is for direct shares.
I is
for indirect shares.
D/I
refers to the Direct or Indirect
shares traded vs. held. |
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Forms:
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A
Form 4 is a form filed
by an insider to indicate a change
in ownership.
A Form
3 is a form filed by
an insider to indicate an
initial ownership of a security. |
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3m +/-:
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|
This
represents the company's 3 month
price change. The initial price
is based on the closing price
of the stock on the day the transaction
took place. Purchases & sales
are viewed as long & short
positions respectively.
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Actions:
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|
| B |
Buy |
| S |
Sell |
| OE |
Option
Exercised |
| A |
Acquired |
| D |
Disposed |
| AB |
Automatic
Buy |
| AS |
Automatic
Sell |
| IO |
Initial
Ownership |
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Download:
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|
Download only Transactions
Forms. (Default)
Download
only Summary Infomation.
Download
both Transactions and Summary Data
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| |
Summary (Direct Transactions Only)  |
3 Months |
6 Months |
12 Months |
24 Months |
| Total Shares Bought |
0 |
0 |
36 |
36 |
| Total Buy Value |
$0 |
$0 |
$10,363 |
$10,363 |
| Total People Bought |
0 |
0 |
1 |
1 |
| Total Buy Transactions |
0 |
0 |
2 |
2 |
| Total Shares Sold |
50,937 |
98,981 |
197,031 |
415,864 |
| Total Sell Value |
$15,535,784 |
$28,531,453 |
$55,655,263 |
$101,675,692 |
| Total People Sold |
1 |
8 |
9 |
12 |
| Total Sell Transactions |
2 |
21 |
35 |
59 |
| End Date |
2025-05-18 |
2025-02-14 |
2024-08-16 |
2023-08-17 |
|
| Filer's Name |
Relation Title |
Off-Dir-10% |
Tran. Date |
Form |
Action |
Price |
Mkt Value |
D/I |
Shares |
Holdings |
Rank
|
|
|
| 3m +/- |
|
|
Form |
  Ausiello Dennis A |
Director |
– • – |
2025-08-14 |
4 |
AS |
$430.81 |
$13,729,536 |
D/D |
(31,448) |
911 |
|
- |
|
| Ausiello Dennis A |
Director |
– • – |
2025-08-14 |
4 |
OE |
$72.01 |
$4,130,478 |
D/D |
31,448 |
32,359 |
|
- |
|
| Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
• – – |
2025-07-01 |
4 |
A |
$0.00 |
$0 |
D/D |
7,763 |
21,264 |
|
- |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-06-02 |
4 |
AS |
$306.00 |
$5,904,882 |
D/D |
(19,297) |
48,948 |
|
43% |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-06-02 |
4 |
OE |
$118.05 |
$2,291,057 |
D/D |
19,297 |
68,245 |
|
- |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-05-30 |
4 |
AS |
$304.00 |
$9,630,902 |
D/D |
(31,640) |
48,948 |
|
44% |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-05-30 |
4 |
OE |
$118.05 |
$3,748,149 |
D/D |
31,640 |
80,588 |
|
- |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-05-16 |
4 |
GD |
$0.00 |
$0 |
D/D |
8,376 |
48,948 |
|
- |
|
| Bonney Michael W |
Director |
– • – |
2025-05-15 |
4 |
AS |
$267.14 |
$3,124,217 |
D/D |
(11,250) |
16,804 |
|
55% |
|
| Bonney Michael W |
Director |
– • – |
2025-05-15 |
4 |
OE |
$131.21 |
$1,476,113 |
D/D |
11,250 |
28,054 |
|
- |
|
| Bertozzi Carolyn R |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
775 |
|
- |
|
| Ausiello Dennis A |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
911 |
|
- |
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| Hamburg Margaret A |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
911 |
|
- |
|
| Reitan Colleen F |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
775 |
|
- |
|
| Pyott David E I |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
911 |
|
- |
|
| Schulman Amy W |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
11,961 |
|
- |
|
| Brandicourt Olivier |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
775 |
|
- |
|
| Bonney Michael W |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
16,804 |
|
- |
|
| Kellogg Peter N |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
775 |
|
- |
|
| Sigal Charles Elliott |
Director |
– • – |
2025-05-08 |
4 |
A |
$0.00 |
$0 |
D/D |
775 |
775 |
|
- |
|
| Greenstreet Yvonne |
Chief Executive Officer |
• • – |
2025-05-02 |
4 |
GD |
$0.00 |
$0 |
D/D |
41,311 |
57,324 |
|
- |
|
| Reitan Colleen F |
Director |
– • – |
2025-04-16 |
4 |
S |
$232.86 |
$8,383 |
D/D |
(36) |
0 |
|
-92% |
|
| Garg Pushkal |
CMO & EVP Dev & Med Affairs |
• – – |
2025-03-24 |
4 |
AS |
$300.00 |
$1,633,500 |
D/D |
(5,445) |
20,221 |
|
38% |
|
| Garg Pushkal |
CMO & EVP Dev & Med Affairs |
• – – |
2025-03-24 |
4 |
OE |
$42.22 |
$229,888 |
D/D |
5,445 |
25,666 |
|
- |
|
| Pyott David E I |
Director |
– • – |
2025-03-24 |
4 |
AS |
$299.00 |
$2,224,560 |
D/D |
(7,440) |
136 |
|
38% |
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495 Records found
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Page 1 of 20 |
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6.18 (1.4%) 
