Repligen Corp $531,198,441 Dynavax Technologies Corp $73,573,446 Adolor Corp $0 Arqule Inc $15,426,100 Astex Pharmaceuticals Inc $0 Infinity Pharmaceuticals Inc $1 XOMA Corporation $42,686,885 Alpine Immune Sciences Inc $13,111,661 Glycomimetics Inc $177,977 Xenon Pharmaceuticals Inc. $0 Concert Pharmaceuticals, Inc. $1,419,460 Syndax Pharmaceuticals Inc $1,765,389 Immune Design Corp. $0 Pieris Pharmaceuticals, Inc. $2,970,733 Calithera Biosciences, Inc. $9,609 Five Prime Therapeutics Inc $237,959,230 Cytokinetics Inc $27,437,942 Merus Nv $10,101,220 Ideaya Biosciences, Inc. $0 Kymera Therapeutics, Inc. $0 Eledon Pharmaceuticals Ord Shs $659,175 Olema Pharmaceuticals, Inc. $0 Cytomx Therapeutics, Inc. $0 Repare Therapeutics Inc. $0 Verastem, Inc. $233,215,496 ESSA Pharma Inc $0 Third Harmonic Bio, Inc. $3,602,743 Structure Therapeutics Inc. $188,227,974 Engene Holdings Inc. $29,367,503 Allakos Inc. $22,185,506 Repligen Corp $531,198,441 Dynavax Technologies Corp $73,573,446 Adolor Corp $0 Arqule Inc $15,426,100 Astex Pharmaceuticals Inc $0 Infinity Pharmaceuticals Inc $1 XOMA Corporation $42,686,885 Alpine Immune Sciences Inc $13,111,661 Glycomimetics Inc $177,977 Xenon Pharmaceuticals Inc. $0 Concert Pharmaceuticals, Inc. $1,419,460 Syndax Pharmaceuticals Inc $1,765,389 Immune Design Corp. $0 Pieris Pharmaceuticals, Inc. $2,970,733 Calithera Biosciences, Inc. $9,609 Five Prime Therapeutics Inc $237,959,230 Cytokinetics Inc $27,437,942 Merus Nv $10,101,220 Ideaya Biosciences, Inc. $0 Kymera Therapeutics, Inc. $0 Eledon Pharmaceuticals Ord Shs $659,175 Olema Pharmaceuticals, Inc. $0 Cytomx Therapeutics, Inc. $0 Repare Therapeutics Inc. $0 Verastem, Inc. $233,215,496 ESSA Pharma Inc $0 Third Harmonic Bio, Inc. $3,602,743 Structure Therapeutics Inc. $188,227,974 Engene Holdings Inc. $29,367,503 Allakos Inc. $22,185,506