| |
Company
Roster
|
|
Total
Insiders : |
44 |
|
|
|
Total
Direct Shares :
|
2,724,726 |
|
|
Total
Indirect Shares :
|
109,988,286 |
| |
%
Held by Insiders:
|
3.42% |
|
|
| |
| Filer's Name |
Relation |
Direct Date |
Direct Shares |
Indirect Date |
Indirect Shares |
  Yen Kristen |
|
2025-12-15 |
27,239 |
|
0 |
| Manning Meredith |
|
2025-12-15 |
43,429 |
2024-07-17 |
0 |
| Mackaness James H |
|
2025-12-15 |
103,163 |
2020-01-23 |
0 |
| Anish Bhatnagar |
|
2025-12-15 |
469,456 |
2015-08-12 |
0 |
| Huang Michael F. |
|
2025-12-15 |
36,005 |
2024-07-17 |
0 |
| Hirano Patricia C |
|
2025-12-15 |
12,302 |
|
0 |
| Norrett Kevin |
|
2025-11-17 |
14,286 |
2025-11-17 |
0 |
| Joshi Manher |
|
2025-11-10 |
16,071 |
2025-11-10 |
0 |
| Hahn Mark W |
|
2025-10-13 |
10,046 |
2025-10-13 |
0 |
| Pauls Matthew |
|
2025-06-05 |
10,491 |
2024-06-06 |
0 |
| Harris William G |
|
2025-06-05 |
19,392 |
2016-10-06 |
0 |
| Bir Dawn Carter |
|
2025-06-05 |
16,991 |
2024-08-15 |
0 |
| Volck Birgitte |
|
2025-06-05 |
17,536 |
2020-01-22 |
0 |
| Sinclair Andrew |
|
2025-06-05 |
10,491 |
2022-03-29 |
18,022,602 |
| Mario Ernest |
|
2024-06-06 |
193,066 |
2024-06-06 |
21,789 |
| Vivo Opportunity Fund Holdings, L.p. |
10% Owner |
2023-10-02 |
0 |
2025-03-28 |
4,458,294 |
| Abingworth Bioventures Vii Lp |
10% Owner |
2023-09-28 |
0 |
2023-09-28 |
1,531,436 |
| Collinson Stuart J |
Director |
2020-07-31 |
1,018 |
2018-02-05 |
7,251,728 |
| Melincoff Gwen A |
Director |
2019-11-19 |
10,000 |
2019-11-19 |
0 |
| Abingworth Llp |
10% Owner |
2019-10-25 |
0 |
2022-03-29 |
18,022,602 |
| Bioasia Investments Iv Llc |
10% Owner |
2019-05-17 |
0 |
2019-05-20 |
0 |
| Schuler Jack W |
|
2018-12-21 |
0 |
2022-12-09 |
36,595 |
| Feinberg Larry N |
10% Owner |
2018-12-19 |
0 |
2018-12-19 |
329,158 |
| Oracle Partners Lp |
10% Owner |
2018-05-14 |
0 |
2020-06-08 |
3,670,384 |
| Technology Partners Affiliates Vii Lp |
10% Owner |
2018-03-07 |
0 |
2018-09-13 |
36,823 |
| Kirnon Stephen |
Director |
2018-02-05 |
14,996 |
2017-04-07 |
0 |
| Glasheen James Walter |
Director, 10% Owner |
2018-02-05 |
1,419,489 |
2018-02-05 |
7,050,691 |
| Dalal Rajen |
Director |
2018-02-05 |
12,056 |
2017-01-23 |
0 |
| Engelsen Steinar J |
Director |
2018-02-05 |
41,831 |
|
0 |
| Shah Mahendra |
Director |
2018-02-05 |
27,153 |
2017-03-07 |
0 |
| Vivo Ventures V, Llc |
10% Owner |
2017-10-02 |
45,059 |
2017-10-02 |
14,241,635 |
| Forward Ventures V Lp |
10% Owner |
2017-03-07 |
0 |
2017-03-07 |
7,251,728 |
| Vivo Ventures Fund V, L.p. |
10% Owner |
2017-03-07 |
0 |
2018-05-14 |
49,456 |
| Otoole David D |
See Remarks |
2016-08-18 |
44,750 |
2015-03-13 |
0 |
| Vivo Ventures V Affiliates Fund, L.p. |
10% Owner |
2015-08-12 |
0 |
2019-12-02 |
3,633,805 |
| Teknoinvest Viii Gp Ks |
10% Owner |
2014-11-12 |
108,410 |
2014-11-12 |
90,155 |
| Wondka Anthony |
|
|
0 |
|
0 |
| Wolter Jonathan |
|
|
0 |
|
0 |
| Carlyle Genesis Uk Llc |
10% Owner |
|
0 |
2022-08-01 |
18,022,602 |
| Nabhan Antoun |
|
|
0 |
|
0 |
| Kung Frank |
10% Owner |
|
0 |
2014-11-12 |
31,758 |
| Engleman Edgar |
Director, 10% Owner |
|
0 |
2018-02-05 |
4,027,292 |
| Phelps Gina |
|
|
0 |
|
0 |
| Edelman Joseph |
10% Owner |
|
0 |
2023-06-06 |
2,207,753 |
|
