| |
Company
Roster
|
|
Total
Insiders : |
38 |
|
|
|
Total
Direct Shares :
|
20,416,385 |
|
|
Total
Indirect Shares :
|
1,920,139 |
| |
%
Held by Insiders:
|
181.16% |
|
|
| |
| Filer's Name |
Relation |
Direct Date |
Direct Shares |
Indirect Date |
Indirect Shares |
  Wyszomierski Jack L |
|
2025-05-21 |
18,504 |
2012-11-13 |
0 |
| Perry Matthew D |
|
2025-05-21 |
23,840 |
2017-03-02 |
0 |
| Kosacz Barbara |
|
2025-05-21 |
5,971 |
|
0 |
| Hernday Natasha |
|
2025-05-21 |
9,006 |
2020-12-15 |
0 |
| Franklin Heather L |
|
2025-05-21 |
5,971 |
2025-05-21 |
0 |
| Hughes Owen |
|
2025-05-20 |
64,701 |
2025-05-20 |
295 |
| Burns Thomas M. |
|
2025-05-20 |
26,563 |
2025-05-20 |
6,130 |
| Lampert Mark N |
10% Owner |
2025-05-16 |
1,267,545 |
2025-01-24 |
0 |
| Limber Joseph M |
|
2025-04-07 |
16,208 |
2014-03-10 |
0 |
| Sitko Bradley |
|
2025-04-07 |
16,842 |
2025-04-07 |
4,561 |
| Neal James R |
|
2022-07-15 |
11,822 |
2022-07-15 |
21,560 |
| Van Ness W Denman |
|
2021-03-15 |
15,643 |
2021-03-15 |
1 |
| Bvf Ii Gp Llc |
10% Owner |
2020-03-13 |
2,250,990 |
|
0 |
| Varian John |
Director |
2017-05-16 |
2,344 |
2017-05-16 |
3,651 |
| Scannon Patrick J Md Phd |
Exec. VP & CSO, Exec. VP & CSO |
2016-12-21 |
8,217 |
2016-12-21 |
1,929 |
| Walbert Timothy P |
Director |
2016-07-21 |
129,314 |
2012-11-13 |
0 |
| Rubin Paul D |
Sr. VP Clinical Dev. & CMO |
2016-03-22 |
326,601 |
2016-03-22 |
13,422 |
| Bowes William K Jr |
Director |
2015-05-28 |
79,339 |
2015-05-28 |
1,000 |
| Kurland Fred |
CFO & VP Finance |
2015-04-06 |
75,461 |
2015-04-06 |
27,391 |
| Klein Thomas |
Chief Commercial Officer |
2015-03-18 |
185,680 |
2015-03-18 |
4,660 |
| Baker Bros. Advisors (gp) Llc |
Director, 10% Owner |
2014-05-22 |
0 |
2014-05-22 |
518,849 |
| Baker Felix |
Director, 10% Owner |
2012-10-29 |
0 |
2012-10-29 |
480,639 |
| 14159, L.p. |
Director, 10% Owner |
2012-07-19 |
360,231 |
2013-05-23 |
489,039 |
| Baker Brothers Life Sciences Lp |
Director |
2012-07-19 |
13,606,093 |
|
0 |
| 667, L.p. |
Director |
2012-07-19 |
1,585,591 |
|
0 |
| Neu Kelvin |
Director |
2012-07-19 |
16,800 |
2012-07-19 |
0 |
| Margolin Christopher J |
VP, General Counsel & Secy |
2011-12-30 |
5,048 |
2011-12-30 |
15,853 |
| Castello John L |
President, CEO and, Director |
2007-12-31 |
128,670 |
2007-12-31 |
63,870 |
| Engle Steven B |
Chairman, CEO & President, Director |
2007-12-31 |
0 |
2010-12-31 |
4,523 |
| Boyle J David Ii |
VP, Finance, and CFO |
2007-03-15 |
18,934 |
2005-08-17 |
0 |
| Dellio Clarence L |
Sr VP, Operations and COO |
2005-05-11 |
101,456 |
2005-05-11 |
15,976 |
| Davis Peter B |
VP, Finance & CFO |
2005-03-17 |
0 |
2005-03-17 |
135,621 |
| Andress James G |
Director |
2004-05-21 |
2,000 |
2004-05-21 |
0 |
| Kornberg Arthur Md |
Director |
2004-05-07 |
11,000 |
2007-08-17 |
20,000 |
| Mendell Steven C |
Director |
2004-04-13 |
40,000 |
2004-04-13 |
631 |
| Baker Julian |
Former 10% owner |
|
0 |
2015-07-22 |
90,538 |
| Datta Deepshikha |
|
|
0 |
|
0 |
| Fisher Charles J Jr |
|
|
0 |
|
0 |
|
2.29 (8.33%) 
