| |
Company
Roster
|
|
Total
Insiders : |
38 |
|
|
|
Total
Direct Shares :
|
29,113,503 |
|
|
Total
Indirect Shares :
|
15,534,902 |
| |
%
Held by Insiders:
|
71.95% |
|
|
| |
| Filer's Name |
Relation |
Direct Date |
Direct Shares |
Indirect Date |
Indirect Shares |
  Alta Embarcadero Partners III Llc |
10% Owner |
2010-01-06 |
5,799,841 |
2010-01-06 |
16,160 |
| Campbell James N |
Director |
2008-09-08 |
114,000 |
2008-09-08 |
4,000 |
| Nash H Ronald |
10% Owner |
2008-06-25 |
31 |
2007-12-18 |
147,838 |
| Viret Jean-Frederic |
Officer |
2008-03-01 |
6,041 |
2008-03-01 |
500 |
| Sofinnova Venture Partners Vii L P |
10% Owner |
2007-12-18 |
4,906,973 |
|
0 |
| Powell Michael |
Director, 10% Owner |
2007-12-18 |
65 |
2007-12-18 |
4,906,973 |
| Harper James A |
Director |
2007-11-21 |
9,030 |
2007-11-15 |
0 |
| Donahue Nancy E |
Officer |
2007-09-27 |
18,811 |
|
0 |
| Regan John X. |
Officer |
2007-07-25 |
16,064 |
|
0 |
| Mclaughlin John Peter |
Chief Executive Officer, Director |
2007-03-29 |
113,400 |
2007-03-29 |
14,624 |
| Broderick Patrick A |
VP & General Counsel |
2007-02-06 |
12,953 |
2004-11-19 |
0 |
| Huang James Z |
President |
2007-02-06 |
14,024 |
2007-02-06 |
46,149 |
| Burch Ronald M |
Former VP, Development |
2006-04-18 |
26,645 |
2005-12-15 |
0 |
| Kliman Gilbert H |
10% Owner |
2006-03-17 |
12,283 |
2006-03-17 |
21,869 |
| Ehrlich Christopher B |
10% Owner |
2006-02-28 |
2,237 |
2006-02-28 |
21,869 |
| Oronsky Arnold L |
Director, 10% Owner |
2005-12-16 |
0 |
2007-12-18 |
47,263 |
| Jp Morgan Partners Global Investors Selldown Llp |
10% Owner |
2005-12-15 |
2,886,121 |
2005-12-15 |
81,769 |
| J P Morgan Partners Sbic Llc |
10% Owner |
2005-12-15 |
2,866,121 |
2005-12-15 |
44,218 |
| Sweeney Michael B |
Director |
2005-12-15 |
117 |
2005-12-15 |
21,870 |
| Eckert Carter H |
Director |
2005-12-15 |
13,258 |
2005-12-15 |
0 |
| Interwest Management Partners Viii, Llc |
10% Owner |
2005-12-15 |
2,721,685 |
2005-12-15 |
100,704 |
| Cohen Charles |
Director |
2005-12-15 |
0 |
2005-12-15 |
1,916 |
| Brewer Richard B |
Director |
2005-12-08 |
60,000 |
2005-02-17 |
0 |
| Gennevois Daniel J |
Officer |
2005-06-07 |
17,002 |
|
0 |
| Lorenz Todd J |
Chief Medical Officer |
2005-04-22 |
0 |
2005-04-22 |
90,037 |
| Mcevoy Leslie M |
Sr. Vice President, Research |
2005-04-20 |
117,000 |
|
0 |
| Colligan Thomas J |
Director |
2005-02-17 |
10,000 |
2005-02-17 |
0 |
| Jpmp Global Investors L P |
10% Owner |
2004-12-30 |
2,965,692 |
2004-12-30 |
860,527 |
| Powers Richard P |
VP & Chief Financial Officer |
2004-11-19 |
103,780 |
|
0 |
| Dzau Victor J |
Director |
2004-09-13 |
540,958 |
|
0 |
| Bristol Myers Squibb Co |
Former 10% owner |
2004-02-18 |
2,079,002 |
2004-02-18 |
0 |
| Simon Robert John |
Former 10% Owner |
2004-02-18 |
0 |
2004-02-18 |
2,095,224 |
| Buhler Fritz R |
Director |
2004-02-18 |
0 |
2004-02-18 |
121,799 |
| J P Morgan Partners Global Investors Cayman Ii Lp |
10% Owner |
2004-02-18 |
3,680,369 |
2004-02-18 |
27,759 |
| Interwest Partners VIII Lp |
Former 10% owner |
2004-02-18 |
0 |
2004-02-18 |
67,226 |
| Ferguson Rodney A |
Director |
2004-02-18 |
0 |
2005-12-15 |
81,803 |
| Gruener Garrett |
10% Owner |
|
0 |
2007-12-18 |
6,696,645 |
| Janney Daniel |
Director, 10% Owner |
|
0 |
2010-01-06 |
16,160 |
|
