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TANG CAPITAL MANAGEMENT LLC |
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SAN DIEGO |
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CA |
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92121 |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
TARS |
Tarsus Pharmaceuticals, Inc. |
1 |
- |
$0.00 |
$126,103,000 |
2,454,797 |
6.98% |
1,255,000 |
200,000 |
5.543 |
N/A |
|
|
GLPG |
Galapagos NV - ADR |
2 |
- |
$27.99 |
$99,520,000 |
3,961,797 |
5.51% |
40,087,000 |
1,800,597 |
6.063 |
N/A |
|
|
AUPH |
Aurinia Pharmaceuticals Inc |
3 |
- |
$8.47 |
$80,637,000 |
10,029,500 |
4.46% |
4,940,000 |
1,600,000 |
7.924 |
N/A |
|
|
DVAX |
Dynavax Technologies Corp |
4 |
- |
$9.92 |
$74,578,000 |
5,750,000 |
4.13% |
50,953,000 |
3,900,000 |
4.267 |
Drug Manufacturers - ... |
|
|
EOLS |
Evolus Inc |
5 |
- |
$9.21 |
$60,119,000 |
4,997,399 |
3.33% |
4,948,000 |
0 |
8.652 |
N/A |
|
|
KALV |
Kalvista Pharmaceuticals Inc |
6 |
- |
$11.31 |
$57,028,000 |
4,941,798 |
3.15% |
15,577,000 |
47,951 |
9.433 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
7 |
- |
$31.38 |
$56,839,000 |
1,915,708 |
3.14% |
10,949,000 |
360,108 |
3.831 |
N/A |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
8 |
- |
$0.00 |
$55,732,000 |
1,237,107 |
3.08% |
4,578,000 |
0 |
2.308 |
N/A |
|
|
PTCT |
PTC Therapeutics, Inc. |
9 |
- |
$48.84 |
$50,960,000 |
1,000,000 |
2.82% |
19,362,000 |
300,000 |
1.104 |
Biotechnology |
|
|
KNSA |
Kiniksa Pharmaceuticals, Ltd. |
10 |
- |
$27.67 |
$47,054,000 |
2,118,579 |
2.6% |
34,620,000 |
1,489,970 |
5.238 |
N/A |
|
|
VRDN |
Viridian Therapeutics Ors Shs |
11 |
- |
$13.98 |
$37,649,000 |
2,792,925 |
2.08% |
-10,140,000 |
300,000 |
3.103 |
N/A |
|
|
AGLE |
Aeglea Biotherapeutics, Inc. |
12 |
New |
$0.60 |
$33,077,000 |
2,050,000 |
1.83% |
33,077,000 |
2,050,000 |
3.351 |
N/A |
|
|
ITCI |
Intra Cellular Therapies Inc |
13 |
- |
$131.87 |
$29,022,000 |
220,000 |
1.61% |
3,966,000 |
-80,000 |
0.233 |
N/A |
|
|
ANAB |
Anaptysbio Inc |
14 |
- |
$22.20 |
$28,724,000 |
1,545,153 |
1.59% |
11,103,000 |
214,274 |
4.415 |
N/A |
|
|
REPL |
Replimune Group Inc |
15 |
- |
$9.29 |
$28,275,000 |
2,900,000 |
1.56% |
-4,422,000 |
200,000 |
4.01 |
N/A |
|
|
LEGN |
Churchill Cap Corp Iii |
16 |
- |
$35.49 |
$28,162,000 |
830,000 |
1.56% |
13,519,000 |
380,000 |
0.642 |
N/A |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
17 |
- |
$21.57 |
$24,915,000 |
1,500,000 |
1.38% |
-2,610,000 |
0 |
0.933 |
Biotechnology |
|
|
BNTX |
Biontech Se Adr |
18 |
- |
$0.00 |
$24,586,000 |
270,000 |
1.36% |
-6,181,000 |
0 |
0.113 |
N/A |
|
|
SLRN |
Acelyrin, Inc. |
19 |
New |
$2.27 |
$24,251,000 |
9,818,115 |
1.34% |
24,251,000 |
9,818,115 |
10.101 |
N/A |
|
|
JAZZ |
Jazz Pharmaceuticals Inc |
20 |
- |
$109.27 |
$23,589,000 |
190,000 |
1.3% |
6,348,000 |
50,000 |
0.311 |
Biotechnology |
|
|
ANIP |
ANI Pharmaceuticals Inc |
21 |
- |
$67.25 |
$21,257,000 |
317,500 |
1.18% |
3,706,000 |
0 |
1.554 |
Biotechnology |
|
|
RLAY |
Relay Therapeutics, Inc. |
22 |
- |
$3.46 |
$21,138,000 |
8,068,058 |
1.17% |
-12,102,000 |
0 |
4.831 |
N/A |
|
|
CMPX |
Compass Therapeutics Ord Shs |
23 |
- |
$0.00 |
$21,000,000 |
11,052,632 |
1.16% |
12,445,000 |
5,152,632 |
7.993 |
N/A |
|
|
ADMA |
ADMA Biologics Inc |
24 |
- |
$18.21 |
$20,832,000 |
1,050,000 |
1.15% |
11,399,000 |
500,000 |
0.445 |
Biotechnology |
|
|
LENZ |
Lenz Therapeutics |
25 |
- |
$29.31 |
$19,718,000 |
766,940 |
1.09% |
-2,424,000 |
0 |
3.004 |
N/A |
|
|
AZN |
AstraZeneca Plc (ADR) |
26 |
- |
$69.88 |
$18,375,000 |
250,000 |
1.02% |
8,547,000 |
100,000 |
0.01 |
Drug Manufacturers - ... |
|
|
LQDA |
Liquidia Technologies Inc |
27 |
- |
$12.46 |
$17,700,000 |
1,200,000 |
0.98% |
4,764,000 |
100,000 |
1.563 |
N/A |
|
|
NBIX |
Neurocrine Biosciences Inc |
28 |
- |
$125.69 |
$16,590,000 |
150,000 |
0.92% |
-3,885,000 |
0 |
0.161 |
Biotechnology |
|
|
AVDL |
AVADEL Pharmaceuticals Plc |
29 |
- |
$15.99 |
$16,423,000 |
2,097,500 |
0.91% |
684,000 |
600,000 |
2.182 |
Drug Delivery |
|
|
ITOS |
Iteos Therapeutics, Inc. |
30 |
- |
$0.00 |
$16,055,000 |
2,689,200 |
0.89% |
14,352,000 |
2,467,484 |
7.084 |
N/A |
|
|
META |
Meta Platforms Inc |
31 |
- |
$738.09 |
$15,893,000 |
27,575 |
0.88% |
319,000 |
975 |
0.001 |
Internet Service Prov... |
|
|
GSK |
GlaxoSmithKline Plc (ADR) |
32 |
- |
$40.41 |
$15,496,000 |
400,000 |
0.86% |
1,968,000 |
0 |
0.02 |
Drug Manufacturers - ... |
|
|
NVDA |
NVIDIA Corporation |
33 |
- |
$157.99 |
$15,452,000 |
142,569 |
0.85% |
-3,694,000 |
0 |
0.001 |
Semiconductor - Speci... |
|
|
SNY |
Sanofi Aventis (ADR) |
34 |
- |
$48.31 |
$14,974,000 |
270,000 |
0.83% |
1,952,000 |
0 |
0.011 |
Drug Manufacturers - ... |
|
|
AVIR |
Atea Pharmaceuticals, Inc. |
35 |
- |
$0.00 |
$14,352,000 |
4,800,000 |
0.79% |
-1,691,000 |
11,088 |
5.81 |
N/A |
|
|
ALT |
Altimmune, Inc |
36 |
- |
$3.87 |
$13,750,000 |
2,750,000 |
0.76% |
-6,078,000 |
0 |
5.594 |
Diversified Investments |
|
|
ZYME |
Zymeworks Inc |
37 |
- |
$12.55 |
$13,101,000 |
1,100,000 |
0.72% |
-3,003,000 |
0 |
1.571 |
N/A |
|
|
NKTX |
Nkarta, Inc. |
38 |
- |
$0.00 |
$12,982,000 |
7,055,576 |
0.72% |
7,271,000 |
4,761,857 |
9.999 |
N/A |
|
|
CRGX |
Cargo Therapeutics, Inc. |
39 |
- |
$0.00 |
$12,453,000 |
3,059,630 |
0.69% |
3,224,000 |
2,419,630 |
0 |
N/A |
|
|
CYBN |
Cybin Inc |
40 |
- |
$8.39 |
$11,603,000 |
1,830,097 |
0.64% |
-128,000 |
500,000 |
0.203 |
N/A |
|
|
PCVX |
Vaxcyte, Inc. |
41 |
- |
$0.00 |
$11,328,000 |
300,000 |
0.63% |
-13,230,000 |
0 |
0.22 |
N/A |
|
|
KROS |
Keros Therapeutics, Inc. |
42 |
New |
$0.00 |
$11,209,000 |
1,100,000 |
0.62% |
11,209,000 |
1,100,000 |
2.683 |
N/A |
|
|
TDOC |
Teladoc, Inc. |
43 |
- |
$8.71 |
$11,144,000 |
1,400,000 |
0.62% |
-1,582,000 |
0 |
0.966 |
N/A |
|
|
DERM |
Journey Medical Ord Shs |
44 |
- |
$0.00 |
$10,942,000 |
1,854,596 |
0.61% |
4,195,000 |
129,027 |
17.396 |
N/A |
|
|
VNDA |
Vanda Pharmaceuticals Inc. |
45 |
- |
$4.72 |
$10,802,000 |
2,353,307 |
0.6% |
-470,000 |
0 |
3.833 |
Biotechnology |
|
|
BGNE |
Beigene Ltd |
46 |
- |
$242.07 |
$10,070,000 |
37,000 |
0.56% |
3,236,000 |
0 |
0.041 |
N/A |
|
|
ARVN |
Arvinas Holding Company, Llc |
47 |
- |
$7.36 |
$9,784,000 |
1,393,800 |
0.54% |
9,784,000 |
1,393,800 |
1.559 |
N/A |
|
|
HRMY |
Harmony Biosciences Holding... |
48 |
- |
$0.00 |
$9,333,000 |
281,200 |
0.52% |
-343,000 |
0 |
0.442 |
N/A |
|
|
BABA |
Alibaba Group Holding Limited |
49 |
New |
$113.41 |
$9,256,000 |
70,000 |
0.51% |
9,256,000 |
70,000 |
0.003 |
N/A |
|
|
CRSP |
Crispr Therapeutics Ag |
50 |
- |
$48.64 |
$9,069,000 |
266,500 |
0.5% |
-1,420,000 |
0 |
0.377 |
N/A |
|
|
MRNA |
Moderna, Inc. |
51 |
- |
$0.00 |
$8,655,000 |
305,300 |
0.48% |
-3,819,000 |
5,300 |
0.077 |
N/A |
|
|
CGEM |
Cullinan Oncology Ord Shs |
52 |
- |
$0.00 |
$8,487,000 |
1,121,138 |
0.47% |
-2,732,000 |
200,000 |
0.258 |
N/A |
|
|
ELAN |
Elanco Animal Health Inc |
53 |
- |
$14.28 |
$8,401,000 |
800,100 |
0.46% |
-1,287,000 |
100 |
0.163 |
N/A |
|
|
PLRX |
Pliant Therapeutics, Inc. |
54 |
New |
$0.00 |
$8,100,000 |
6,000,000 |
0.45% |
8,100,000 |
6,000,000 |
8.721 |
N/A |
|
|
BLCO |
Bausch & Lomb Corp |
55 |
- |
$13.01 |
$7,975,000 |
550,000 |
0.44% |
-152,000 |
100,000 |
0.157 |
N/A |
|
|
INSM |
Insmed Inc |
56 |
- |
$100.64 |
$7,629,000 |
100,000 |
0.42% |
725,000 |
0 |
0.053 |
Biotechnology |
|
|
PHAT |
Phathom Pharmaceuticals, Inc. |
57 |
- |
$0.00 |
$7,524,000 |
1,200,000 |
0.42% |
3,464,000 |
700,000 |
1.538 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
58 |
- |
$43.43 |
$7,472,000 |
200,000 |
0.41% |
2,942,000 |
100,000 |
0.342 |
N/A |
|
|
HLVX |
Hillevax, Inc. |
59 |
- |
$1.99 |
$7,134,000 |
4,920,000 |
0.39% |
-3,050,000 |
0 |
10.157 |
N/A |
|
|
IBRX |
ImmunityBio, Inc |
60 |
- |
$2.64 |
$7,023,000 |
2,333,333 |
0.39% |
-181,000 |
-480,859 |
0.609 |
N/A |
|
|
NUVB |
Nuvation Bio Ord Shs Class A |
61 |
- |
$10.42 |
$6,864,000 |
3,900,000 |
0.38% |
-3,510,000 |
0 |
1.8 |
N/A |
|
|
EPIX |
ESSA Pharma Inc |
62 |
- |
$0.00 |
$6,794,000 |
4,300,000 |
0.38% |
-903,000 |
0 |
9.777 |
Diagnostic Substances |
|
|
EWTX |
Edgewise Therapeutics, Inc. |
63 |
- |
$13.11 |
$6,600,000 |
300,000 |
0.37% |
-1,410,000 |
0 |
0.291 |
N/A |
|
|
VKTX |
Viking Therapeutics, Inc. |
64 |
- |
$26.50 |
$6,521,000 |
270,000 |
0.36% |
-6,356,000 |
-50,000 |
0.269 |
N/A |
|
|
DSGN |
Design Therapeutics, Inc. |
65 |
- |
$0.00 |
$6,489,000 |
1,680,975 |
0.36% |
-2,649,000 |
200,000 |
3.022 |
N/A |
|
|
REGN |
Regeneron Pharmaceuticals Inc |
66 |
- |
$525.00 |
$6,342,000 |
10,000 |
0.35% |
4,917,000 |
8,000 |
0.01 |
Biotechnology |
|
|
ACET |
Adicet Bio, Inc |
67 |
- |
$0.61 |
$6,209,000 |
8,223,612 |
0.34% |
-1,627,000 |
77,624 |
9.98 |
N/A |
|
|
BIOA |
Bioage Labs, Inc. |
68 |
- |
$4.13 |
$6,016,000 |
1,600,000 |
0.33% |
-1,617,000 |
281,639 |
4.467 |
N/A |
|
|
BCRX |
Biocryst Pharmaceuticals Inc |
69 |
- |
$8.96 |
$6,000,000 |
800,000 |
0.33% |
-16,000 |
0 |
0.422 |
Biotechnology |
|
|
IOVA |
Iovance Biotherapeutics Inc |
70 |
- |
$1.72 |
$5,994,000 |
1,800,000 |
0.33% |
2,294,000 |
1,300,000 |
0.593 |
N/A |
|
|
ABCL |
Abcellera Biologics Inc. |
71 |
- |
$0.00 |
$5,798,000 |
2,600,000 |
0.32% |
-1,770,000 |
17,184 |
0.966 |
N/A |
|
|
RCKT |
Rocket Pharmaceuticals |
72 |
- |
$2.45 |
$5,670,000 |
850,000 |
0.31% |
-3,758,000 |
100,000 |
0.918 |
N/A |
|
|
HRTX |
Heron Therapeutics Inc |
73 |
- |
$2.07 |
$4,918,000 |
2,235,459 |
0.27% |
1,643,000 |
95,188 |
1.474 |
Synthetics |
|
|
LNTH |
Lantheus Holdings, Inc. |
74 |
- |
$81.86 |
$4,880,000 |
50,000 |
0.27% |
407,000 |
0 |
0.069 |
N/A |
|
|
DNTH |
Dianthus Therapeutics Ord Shs |
75 |
- |
$0.70 |
$4,802,000 |
264,692 |
0.27% |
-968,000 |
0 |
0.814 |
N/A |
|
|
BIIB |
Biogen Idec Inc |
76 |
- |
$125.59 |
$4,789,000 |
35,000 |
0.26% |
-563,000 |
0 |
0.023 |
Biotechnology |
|
|
IONS |
Ionis Pharmaceuticals Inc |
77 |
- |
$39.51 |
$4,526,000 |
150,000 |
0.25% |
-718,000 |
0 |
0.095 |
Drug Manufacturers - ... |
|
|
CTMX |
Cytomx Therapeutics, Inc. |
78 |
- |
$0.00 |
$4,271,000 |
6,717,825 |
0.24% |
-3,260,000 |
-593,935 |
10.31 |
N/A |
|
|
MRUS |
Merus Nv |
79 |
- |
$52.60 |
$4,209,000 |
100,000 |
0.23% |
4,000 |
0 |
0.14 |
N/A |
|
|
CHRS |
Coherus Biosciences, Inc. |
80 |
- |
$0.73 |
$4,114,000 |
5,097,362 |
0.23% |
-923,000 |
1,447,362 |
6.169 |
N/A |
|
|
JANX |
Janux Therapeutics, Inc. |
81 |
- |
$0.00 |
$4,050,000 |
150,000 |
0.22% |
1,373,000 |
100,000 |
0.288 |
N/A |
|
|
CYTK |
Cytokinetics Inc |
82 |
- |
$33.04 |
$4,019,000 |
100,000 |
0.22% |
-685,000 |
0 |
0.073 |
Biotechnology |
|
|
CMPS |
Compass Pathways Plc |
83 |
- |
$0.00 |
$4,004,000 |
1,400,000 |
0.22% |
224,000 |
400,000 |
4.022 |
N/A |
|
|
TGTX |
TG Therapeutics Inc |
84 |
- |
$35.99 |
$3,943,000 |
100,000 |
0.22% |
933,000 |
0 |
0.078 |
Drug Manufacturers - ... |
|
|
GMXAY |
GENMAB AS |
85 |
- |
$20.66 |
$3,916,000 |
200,000 |
0.22% |
1,829,000 |
100,000 |
0.222 |
N/A |
|
|
NVAX |
Novavax Inc |
86 |
- |
$0.36 |
$3,846,000 |
600,000 |
0.21% |
-978,000 |
0 |
0.505 |
Biotechnology |
|
|
ARE |
Alexandria Real Estate Equi... |
87 |
- |
$72.63 |
$3,700,000 |
40,000 |
0.2% |
-202,000 |
0 |
0.023 |
REIT - Office |
|
|
VERA |
Vera Therapeutics, Inc. |
88 |
New |
$0.00 |
$3,603,000 |
150,000 |
0.2% |
3,603,000 |
150,000 |
0.274 |
N/A |
|
|
SLNO |
Soleno Therapeutics Inc |
89 |
- |
$0.16 |
$3,573,000 |
50,000 |
0.2% |
1,325,000 |
0 |
0.063 |
N/A |
|
|
VTYX |
Ventyx Biosciences, Inc. |
90 |
- |
$2.14 |
$3,565,000 |
3,100,000 |
0.2% |
-3,224,000 |
0 |
4.387 |
N/A |
|
|
NUVL |
Nuvalent, Inc. |
91 |
- |
$0.00 |
$3,546,000 |
50,000 |
0.2% |
-368,000 |
0 |
0.071 |
N/A |
|
|
RVMD |
Revolution Medicines, Inc. |
92 |
- |
$36.79 |
$3,536,000 |
100,000 |
0.2% |
-838,000 |
0 |
0.059 |
N/A |
|
|
KZR |
Kezar Life Sciences, Inc. |
93 |
- |
$4.58 |
$3,514,000 |
720,000 |
0.19% |
-1,324,000 |
0 |
1.053 |
N/A |
|
|
BHVN |
Biohaven Ltd. |
94 |
- |
$14.11 |
$3,366,000 |
140,000 |
0.19% |
-1,863,000 |
0 |
0.148 |
N/A |
|
|
STOK |
Stoke Therapeutics, Inc. |
95 |
- |
$11.35 |
$3,325,000 |
500,000 |
0.18% |
16,000 |
200,000 |
0.798 |
N/A |
|
|
SWTX |
Springworks Therapeutics, Inc. |
96 |
- |
$0.00 |
$3,277,000 |
74,265 |
0.18% |
594,000 |
0 |
0.089 |
N/A |
|
|
VIR |
Vir Biotechnology, Inc. |
97 |
New |
$0.00 |
$3,240,000 |
500,000 |
0.18% |
3,240,000 |
500,000 |
0.392 |
N/A |
|
|
THRD |
Third Harmonic Bio, Inc. |
98 |
- |
$5.43 |
$3,226,000 |
929,727 |
0.18% |
1,682,000 |
779,727 |
2.066 |
N/A |
|
|
DTIL |
Precision Biosciences Inc |
99 |
- |
$4.20 |
$3,212,000 |
673,332 |
0.18% |
647,000 |
0 |
0.608 |
N/A |
|
|
BDTX |
Black Diamond Therapeutics,... |
100 |
- |
$2.48 |
$3,209,000 |
2,070,209 |
0.18% |
-1,221,000 |
0 |
4.009 |
N/A |
|
