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| Name: |
SPHERA FUNDS MANAGEMENT LTD. |
| City: |
Tel Aviv |
| State: |
L3 |
| Zip: |
64739 |
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Menu
 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
TEVA |
Teva Pharmaceutical Industr... |
1 |
- |
$16.76 |
$26,664,000 |
1,889,700 |
4.32% |
887,000 |
-579,400 |
0.172 |
Drug Manufacturers - ... |
|
|
SNY |
Sanofi Aventis (ADR) |
2 |
- |
$49.00 |
$24,276,000 |
499,515 |
3.93% |
-565,000 |
0 |
0.02 |
Drug Manufacturers - ... |
|
|
NICE |
NICE Systems Ltd (ADR) |
3 |
- |
$190.10 |
$22,382,000 |
85,881 |
3.62% |
8,872,000 |
18,163 |
0.137 |
Computer Peripherals |
|
|
CYTK |
Cytokinetics Inc |
4 |
- |
$48.98 |
$19,748,000 |
281,671 |
3.2% |
1,061,000 |
57,851 |
0.23 |
Biotechnology |
|
|
SNDX |
Syndax Pharmaceuticals Inc |
5 |
- |
$20.11 |
$19,349,000 |
812,964 |
3.13% |
2,645,000 |
40,000 |
0.865 |
N/A |
|
|
BBIO |
Bridgebio Pharma, Inc. |
6 |
- |
$27.76 |
$18,118,000 |
585,956 |
2.93% |
6,728,000 |
303,810 |
0.337 |
N/A |
|
|
BIIB |
Biogen Idec Inc |
7 |
- |
$218.06 |
$15,233,000 |
70,646 |
2.47% |
3,240,000 |
24,300 |
0.046 |
Biotechnology |
|
|
JSPR |
Jasper Therapeutics Ord Shs |
8 |
- |
$15.12 |
$14,834,000 |
505,242 |
2.4% |
9,208,000 |
-207,821 |
0.497 |
N/A |
|
|
ISR |
IsoRay, Inc. |
9 |
- |
$1.51 |
$14,808,000 |
12,443,621 |
2.4% |
14,798,000 |
12,417,950 |
22.618 |
Medical Instruments &... |
|
|
MRK |
Merck & Co Inc |
10 |
- |
$131.20 |
$13,670,000 |
103,600 |
2.21% |
195,000 |
-20,000 |
0.004 |
Drug Manufacturers - ... |
|
|
KURA |
Kura Oncology Inc |
11 |
- |
$21.43 |
$13,029,000 |
610,826 |
2.11% |
2,916,000 |
-92,461 |
0.729 |
N/A |
|
|
AZN |
AstraZeneca Plc (ADR) |
12 |
- |
$78.18 |
$12,877,000 |
190,060 |
2.09% |
750,000 |
10,000 |
0.007 |
Drug Manufacturers - ... |
|
|
S |
Sentinelone, Inc. |
13 |
- |
$21.72 |
$12,840,000 |
550,818 |
2.08% |
6,984,000 |
337,400 |
0.221 |
N/A |
|
|
JNJ |
Johnson & Johnson |
14 |
- |
$149.70 |
$12,628,000 |
79,831 |
2.04% |
115,000 |
0 |
0.003 |
Drug Manufacturers - ... |
|
|
FB |
Meta Platforms Inc |
15 |
- |
$465.78 |
$12,353,000 |
25,439 |
2% |
211,000 |
-8,864 |
0.001 |
Internet Service Prov... |
|
|
CLDX |
Celldex Therapeutics Inc |
16 |
- |
$36.32 |
$11,626,000 |
276,996 |
1.88% |
-892,000 |
-38,648 |
0.44 |
Diagnostic Substances |
|
|
MSFT |
Microsoft Corp |
17 |
- |
$427.00 |
$11,590,000 |
27,548 |
1.88% |
2,622,000 |
3,700 |
0 |
Application Software |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
18 |
- |
$39.90 |
$11,138,000 |
238,544 |
1.8% |
1,524,000 |
37,500 |
0.291 |
Restaurants |
|
|
LLY |
Eli Lilly & Co |
19 |
- |
$808.45 |
$11,039,000 |
14,190 |
1.79% |
2,767,000 |
0 |
0.001 |
Drug Manufacturers - ... |
|
|
PRAX |
Praxis Precision Medicines,... |
20 |
- |
$0.00 |
$10,809,000 |
177,139 |
1.75% |
3,479,000 |
-151,847 |
0.338 |
N/A |
|
|
NVO |
Novo Nordisk A/S (ADR) |
21 |
- |
$135.57 |
$10,667,000 |
83,080 |
1.73% |
1,038,000 |
-10,000 |
0.005 |
Drug Manufacturers - ... |
|
|
CYBN |
Cybin Inc |
22 |
New |
$0.35 |
$10,578,000 |
25,581,395 |
1.71% |
10,578,000 |
25,581,395 |
16.131 |
N/A |
|
|
INZY |
Inozyme Pharma, Inc. |
23 |
- |
$0.00 |
$10,516,000 |
1,372,907 |
1.7% |
3,858,000 |
-190,000 |
2.223 |
N/A |
|
|
FROG |
Jfrog Ltd |
24 |
- |
$33.25 |
$9,922,000 |
224,381 |
1.61% |
6,118,000 |
114,476 |
0.253 |
N/A |
|
|
AMZN |
Amazon.com Inc |
25 |
- |
$181.05 |
$9,818,000 |
54,432 |
1.59% |
1,359,000 |
-1,244 |
0.001 |
Internet Software & S... |
|
|
FUSN |
Fusion Pharmaceuticals Inc. |
26 |
- |
$21.50 |
$9,574,000 |
449,041 |
1.55% |
-859,000 |
-636,598 |
0.62 |
N/A |
|
|
PHVS |
Pharvaris N V Ord Shs |
27 |
- |
$0.00 |
$9,079,000 |
392,877 |
1.47% |
2,207,000 |
147,877 |
0.949 |
N/A |
|
|
MLYS |
Mineralys Therapeutics, Inc. |
28 |
- |
$0.00 |
$8,505,000 |
658,803 |
1.38% |
2,110,000 |
-84,788 |
1.612 |
N/A |
|
|
DAWN |
Day One Biopharmaceuticals,... |
29 |
- |
$0.00 |
$8,138,000 |
492,627 |
1.32% |
648,000 |
-20,373 |
0.566 |
N/A |
|
|
GLBE |
Global E Online Ord Shs |
30 |
- |
$29.45 |
$7,589,000 |
208,784 |
1.23% |
-3,103,000 |
-61,010 |
0.147 |
N/A |
|
|
WIX |
WIX.COM Ltd |
31 |
- |
$165.21 |
$7,270,000 |
52,877 |
1.18% |
199,000 |
-4,600 |
0.095 |
N/A |
|
|
SRPT |
Sarepta Therapeutics Inc |
32 |
- |
$127.13 |
$7,200,000 |
55,614 |
1.17% |
5,995,000 |
43,114 |
0.066 |
Drug Manufacturers - ... |
|
|
IMTX |
Immatics N.V |
33 |
- |
$9.82 |
$7,001,000 |
666,111 |
1.13% |
461,000 |
45,000 |
1.059 |
N/A |
|
|
ABBV |
Abbvie Inc. |
34 |
- |
$158.26 |
$6,920,000 |
38,000 |
1.12% |
-209,000 |
-8,000 |
0.002 |
Drug Manufacturers - ... |
|
|
OTLK |
Outlook Therapeutics Inc |
35 |
New |
$7.53 |
$6,823,000 |
571,429 |
1.1% |
6,823,000 |
571,429 |
0.465 |
N/A |
|
|
MRUS |
Merus Nv |
36 |
- |
$44.07 |
$6,724,000 |
149,333 |
1.09% |
390,000 |
-81,000 |
0.259 |
N/A |
|
|
AMAT |
Applied Materials Inc |
37 |
New |
$217.95 |
$6,599,000 |
32,000 |
1.07% |
6,599,000 |
32,000 |
0.004 |
Semiconductor Equipme... |
|
|
CAMT |
Camtek Ltd |
38 |
New |
$104.21 |
$6,275,000 |
74,909 |
1.02% |
6,275,000 |
74,909 |
0.191 |
Scientific & Technica... |
|
|
NVMI |
Nova Measuring Instruments,... |
39 |
- |
$210.77 |
$6,227,000 |
35,106 |
1.01% |
-11,908,000 |
-96,894 |
0.124 |
Semiconductor Equipme... |
|
|
TSEM |
Tower Semiconductor Ltd (USA) |
40 |
- |
$36.81 |
$6,008,000 |
179,600 |
0.97% |
-10,116,000 |
-348,700 |
0.167 |
Semiconductor - Integ... |
|
|
ETNB |
89bio, Inc. |
41 |
- |
$8.18 |
$6,005,000 |
515,882 |
0.97% |
1,440,000 |
107,208 |
0.527 |
N/A |
|
|
VIGL |
Vigil Neuroscience, Inc. |
42 |
- |
$0.00 |
$5,901,000 |
1,730,414 |
0.96% |
4,092,000 |
1,195,294 |
6.121 |
N/A |
|
|
ENPH |
Enphase Energy, Inc. |
43 |
- |
$117.50 |
$5,708,000 |
47,183 |
0.92% |
1,110,000 |
12,383 |
0.037 |
Semiconductor Equipme... |
|
|
VTYX |
Ventyx Biosciences, Inc. |
44 |
- |
$4.45 |
$5,460,000 |
992,749 |
0.88% |
5,015,000 |
812,749 |
1.974 |
N/A |
|
|
TBLA |
Taboolacom Ord Shs |
45 |
- |
$0.00 |
$5,288,000 |
1,191,070 |
0.86% |
-2,181,000 |
-533,878 |
0.565 |
N/A |
|
|
FDMT |
4d Molecular Therapeutics Inc. |
46 |
New |
$0.00 |
$5,166,000 |
162,161 |
0.84% |
5,166,000 |
162,161 |
0.329 |
N/A |
|
|
INCY |
Incyte Corp |
47 |
- |
$57.45 |
$5,102,000 |
89,556 |
0.83% |
-521,000 |
0 |
0.041 |
Biotechnology |
|
|
RCKT |
Rocket Pharmaceuticals |
48 |
- |
$21.72 |
$4,949,000 |
183,722 |
0.8% |
-769,000 |
-7,061 |
0.198 |
N/A |
|
|
NVS |
Novartis AG (ADR) |
49 |
- |
$101.11 |
$4,837,000 |
50,000 |
0.78% |
-1,221,000 |
-10,000 |
0.002 |
Drug Manufacturers - ... |
|
|
CPRX |
Catalyst Pharmaceutical Par... |
50 |
New |
$15.92 |
$4,591,000 |
288,000 |
0.74% |
4,591,000 |
288,000 |
0.278 |
Drugs - Generic |
|
|
GSK |
GlaxoSmithKline Plc (ADR) |
51 |
- |
$40.41 |
$4,287,000 |
100,000 |
0.69% |
581,000 |
0 |
0.005 |
Drug Manufacturers - ... |
|
|
VTGN |
Vistagen Therapeutics Inc |
52 |
- |
$4.10 |
$4,269,000 |
808,550 |
0.69% |
113,000 |
0 |
2.991 |
Biotechnology |
|
|
APLT |
Applied Therapeutics Inc. |
53 |
New |
$0.00 |
$4,209,000 |
619,029 |
0.68% |
4,209,000 |
619,029 |
0.802 |
N/A |
|
|
HOWL |
Werewolf Therapeutics, Inc. |
54 |
- |
$0.00 |
$4,062,000 |
626,810 |
0.66% |
1,643,000 |
0 |
1.542 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
55 |
New |
$0.00 |
$4,053,000 |
160,445 |
0.66% |
4,053,000 |
160,445 |
0.262 |
N/A |
|
|
PLRX |
Pliant Therapeutics, Inc. |
56 |
- |
$0.00 |
$3,852,000 |
258,554 |
0.62% |
347,000 |
65,000 |
0.411 |
N/A |
|
|
PMN |
Promis Neurosciences Ord Shs |
57 |
- |
$1.68 |
$3,503,000 |
1,834,047 |
0.57% |
1,394,000 |
5 |
21.376 |
N/A |
|
|
SWTX |
Springworks Therapeutics, Inc. |
58 |
- |
$0.00 |
$3,459,000 |
70,269 |
0.56% |
-2,756,000 |
-100,001 |
0.089 |
N/A |
|
|
ALEC |
Alector, Inc. |
59 |
New |
$5.26 |
$3,371,000 |
560,000 |
0.55% |
3,371,000 |
560,000 |
0.707 |
N/A |
|
|
IRON |
Disc Medicine, Inc |
60 |
- |
$33.35 |
$3,044,000 |
48,886 |
0.49% |
3,044,000 |
48,886 |
0.203 |
N/A |
|
|
AAPL |
Apple Inc |
61 |
New |
$186.88 |
$3,001,000 |
17,500 |
0.49% |
3,001,000 |
17,500 |
0 |
Personal Computers |
|
|
ENLT |
Enlight Renewable Energy Or... |
62 |
- |
$17.26 |
$2,864,000 |
169,280 |
0.46% |
-376,000 |
0 |
0.144 |
N/A |
|
|
SEDG |
Solaredge Technologies Inc |
63 |
- |
$47.21 |
$2,852,000 |
40,175 |
0.46% |
-1,641,000 |
-7,825 |
0.078 |
N/A |
|
|
RZLT |
Rezolute, Inc |
64 |
- |
$3.06 |
$2,542,000 |
996,710 |
0.41% |
1,553,000 |
0 |
2.968 |
N/A |
|
|
QCOM |
QUALCOMM Inc |
65 |
New |
$201.76 |
$2,540,000 |
15,000 |
0.41% |
2,540,000 |
15,000 |
0.001 |
Communication Equipment |
|
|
PFE |
Pfizer Inc |
66 |
- |
$28.69 |
$2,498,000 |
90,000 |
0.4% |
-93,000 |
0 |
0.002 |
Drug Manufacturers - ... |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
67 |
New |
$15.54 |
$2,311,000 |
125,000 |
0.37% |
2,311,000 |
125,000 |
0.078 |
Biotechnology |
|
|
ELEV |
Elevation Oncology, Inc. |
68 |
- |
$3.69 |
$2,206,000 |
430,000 |
0.36% |
1,723,000 |
-470,000 |
1.014 |
N/A |
|
|
ESTC |
Elastic N.v. |
69 |
New |
$0.00 |
$2,005,000 |
20,000 |
0.32% |
2,005,000 |
20,000 |
0.023 |
N/A |
|
|
AMD |
Advanced Micro Devices Inc |
71 |
- |
$160.43 |
$1,985,000 |
11,000 |
0.32% |
-5,443,000 |
-39,387 |
0 |
Semiconductor- Broad... |
|
|
CGEN |
Compugen Ltd (USA) |
70 |
- |
$2.27 |
$1,985,000 |
769,239 |
0.32% |
462,000 |
0 |
0.929 |
Biotechnology |
|
|
NTR |
Nutrien Ltd |
72 |
New |
$59.21 |
$1,940,000 |
35,730 |
0.31% |
1,940,000 |
35,730 |
0.006 |
N/A |
|
|
KZR |
Kezar Life Sciences, Inc. |
73 |
- |
$0.73 |
$1,850,000 |
2,051,676 |
0.3% |
-94,000 |
0 |
3.001 |
N/A |
|
|
APRE |
Aprea Therapeutics, Inc. |
74 |
New |
$0.00 |
$1,806,000 |
270,000 |
0.29% |
1,806,000 |
270,000 |
1.286 |
N/A |
|
|
ALPN |
Alpine Immune Sciences Inc |
75 |
- |
$64.97 |
$1,777,000 |
44,841 |
0.29% |
-2,699,000 |
-190,000 |
0.068 |
N/A |
|
|
FIVN |
Five9, Inc. |
76 |
- |
$50.51 |
$1,708,000 |
27,500 |
0.28% |
528,000 |
12,500 |
0.037 |
N/A |
|
|
CRGX |
Cargo Therapeutics, Inc. |
77 |
- |
$0.00 |
$1,674,000 |
75,000 |
0.27% |
-62,000 |
0 |
0 |
N/A |
|
|
ATXS |
Astria Therapeutics, Inc |
78 |
- |
$9.02 |
$1,588,000 |
112,842 |
0.26% |
-7,253,000 |
-1,038,303 |
0.206 |
N/A |
|
|
PRME |
Prime Medicine, Inc. |
79 |
- |
$6.94 |
$1,437,000 |
205,242 |
0.23% |
782,000 |
131,262 |
0.211 |
N/A |
|
|
UPWK |
Upwork Inc |
80 |
- |
$11.10 |
$1,434,000 |
117,000 |
0.23% |
-2,325,000 |
-135,784 |
0.097 |
N/A |
|
|
CRBP |
Corbus Pharmaceuticals Hold... |
81 |
New |
$41.38 |
$1,373,000 |
35,000 |
0.22% |
1,373,000 |
35,000 |
0.028 |
N/A |
|
|
AVGO |
Broadcom Limited |
82 |
- |
$1,393.29 |
$1,327,000 |
1,001 |
0.21% |
-682,000 |
-799 |
0 |
Semiconductor- Broad... |
|
|
GERN |
Geron Corporation |
83 |
New |
$3.49 |
$1,268,000 |
384,356 |
0.21% |
1,268,000 |
384,356 |
0.071 |
Drug Manufacturers - ... |
|
|
LVTX |
Lava Therapeutics N V Ord Shs |
84 |
New |
$0.00 |
$1,224,000 |
367,582 |
0.2% |
1,224,000 |
367,582 |
1.45 |
N/A |
|
|
GOSS |
Gossamer Bio Inc |
85 |
- |
$0.64 |
$1,212,000 |
1,027,134 |
0.2% |
-9,000 |
-310,956 |
0.456 |
N/A |
|
|
VRNS |
Varonis Systems Inc |
86 |
New |
$44.55 |
$943,000 |
20,000 |
0.15% |
943,000 |
20,000 |
0.019 |
N/A |
|
|
AMLX |
Amylyx Pharmaceuticals, Inc. |
87 |
- |
$0.00 |
$759,000 |
267,250 |
0.12% |
-1,944,000 |
83,600 |
0.396 |
N/A |
|
|
ICL |
Icl Group Inc |
88 |
- |
$3.37 |
$702,000 |
130,475 |
0.11% |
-1,402,000 |
-289,525 |
0.01 |
N/A |
|
|
SELB |
Selecta Biosciences Inc |
89 |
- |
$0.50 |
$489,000 |
25,071 |
0.08% |
-30,000 |
-727,066 |
0.023 |
N/A |
|
|
ANRO |
Alto Neuroscience, Inc. |
90 |
New |
$11.76 |
$468,000 |
30,500 |
0.08% |
468,000 |
30,500 |
0.113 |
N/A |
|
|
IMTXW |
Immatics N.V - Warrants |
91 |
- |
$0.00 |
$270,000 |
100,000 |
0.04% |
-22,000 |
0 |
1.111 |
N/A |
|
|
ARBE |
Arbe Robotics Ltd |
92 |
- |
$1.68 |
$90,000 |
43,165 |
0.01% |
-4,000 |
0 |
0.056 |
N/A |
|
|
ORIC |
Oric Pharmaceuticals, Inc. |
100 |
Closed |
$0.00 |
$0 |
0 |
0% |
-1,167,000 |
-126,800 |
0 |
N/A |
|
|
REPL |
Replimune Group Inc |
104 |
Closed |
$5.66 |
$0 |
0 |
0% |
-136,000 |
-16,096 |
0 |
N/A |
|
|
ARWR |
Arrowhead Pharmaceuticals Inc |
94 |
Closed |
$24.67 |
$0 |
0 |
0% |
-4,434,000 |
-144,899 |
0 |
Business Services |
|
|
PTCT |
PTC Therapeutics, Inc. |
99 |
Closed |
$37.13 |
$0 |
0 |
0% |
-3,763,000 |
-136,525 |
0 |
Biotechnology |
|
|
RIGL |
Rigel Pharmaceuticals Inc |
103 |
Closed |
$1.22 |
$0 |
0 |
0% |
-1,781,000 |
-1,228,126 |
0 |
Drug Manufacturers - ... |
|
|
FRLN |
Freeline Therapeutics Hldgs |
98 |
Closed |
$0.00 |
$0 |
0 |
0% |
-105,000 |
-16,445 |
0 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
93 |
Closed |
$46.04 |
$0 |
0 |
0% |
-838,000 |
-30,000 |
0 |
N/A |
|
|
GRCL |
Gracell Biotechnologies Adr... |
109 |
Closed |
$0.00 |
$0 |
0 |
0% |
-5,049,000 |
-502,936 |
0 |
N/A |
|
