Rock Springs Capital Management LP : Portfolio Holdings

Portfolio Summary	View Filing
Filing Report Date :	2025-03-31
Total Value :	$1,742,532,000
Total Value Change :	$-878,578,000
Securities Held Change :	-10

All Securities Held :	95
New Positions :	6
Closed Positions :	16
Increased Positions :	25
Unchanged Positions :	17
Decreased Positions :	47

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Holdings Found : 100		View All Holdings	Currently Viewing: ALL				Page 1 of 1

Menu	Ticker	Company Name	Position Rank	New/Closed Postion	Last Close	Value	Shares Held	% of Portfolio	Value Change	Change In Shares Held	% of Company	Industry
	ARGX	Argenx Se	1	-	$560.14	$104,020,000	175,750	5.97%	-37,184,000	-53,850	0.374	N/A
	LLY	Eli Lilly & Co	2	-	$775.45	$93,741,000	113,500	5.38%	-17,813,000	-31,000	0.012	Drug Manufacturers - ...
	BPMC	Blueprint Medicines Corp	3	-	$128.11	$89,180,000	1,007,569	5.12%	-6,492,000	-89,330	1.527	N/A
	MDGL	Madrigal Pharmaceuticals Inc	4	-	$300.75	$55,215,000	166,698	3.17%	-26,621,000	-98,514	0.648	Diagnostic Substances
	UNH	Unitedhealth Group Inc	5	-	$309.11	$52,637,000	100,500	3.02%	-36,394,000	-75,500	0.011	Health Care Plans
	TVTX	Travere Therapeutics, Inc	6	-	$14.77	$52,348,000	2,921,196	3%	-34,293,000	-2,052,453	3.26	N/A
	ISRG	Intuitive Surgical Inc	7	-	$372.63	$50,518,000	102,000	2.9%	-62,225,000	-114,000	0.029	Medical Appliances & ...
	RARE	Ultragenyx Pharmaceutical Inc	8	-	$36.52	$50,492,000	1,394,434	2.9%	-22,702,000	-345,379	1.514	Restaurants
	PEN	Penumbra Inc	9	-	$256.43	$45,727,000	171,000	2.62%	-11,268,000	-69,000	0.471	N/A
	RVMD	Revolution Medicines, Inc.	10	-	$36.91	$45,319,000	1,281,640	2.6%	-7,749,000	68,383	0.754	N/A
	RYTM	Rhythm Pharmaceuticals, Inc.	11	-	$62.73	$44,187,000	834,188	2.54%	-20,902,000	-328,530	1.176	N/A
	MIRM	Mirum Pharmaceuticals, Inc.	12	-	$0.00	$42,877,000	951,765	2.46%	-17,972,000	-519,799	1.776	N/A
	MRUS	Merus Nv	13	-	$52.99	$41,280,000	980,751	2.37%	3,748,000	88,202	1.369	N/A
	INSM	Insmed Inc	14	-	$99.49	$39,358,000	515,900	2.26%	1,386,000	-34,100	0.272	Biotechnology
	ALNY	Alnylam Pharmaceuticals Inc	15	-	$322.83	$38,680,000	143,250	2.22%	-21,606,000	-112,950	0.116	Biotechnology
	ASND	Ascendis Pharma AS	16	-	$172.22	$33,666,000	216,000	1.93%	-8,323,000	-89,000	0.334	N/A
	ZLAB	Zai Lab Ltd	17	-	$34.74	$32,692,000	904,592	1.88%	-1,495,000	-400,745	1.028	N/A
	XENE	Xenon Pharmaceuticals Inc.	18	-	$0.00	$31,258,000	931,681	1.79%	-17,815,000	-320,178	1.238	N/A
	NBIX	Neurocrine Biosciences Inc	19	-	$125.42	$30,857,000	279,000	1.77%	-67,491,000	-441,500	0.299	Biotechnology
	NUVL	Nuvalent, Inc.	20	-	$0.00	$30,321,000	427,532	1.74%	-3,339,000	-2,462	0.611	N/A
	AGL	Agilon Health, Inc.	21	-	$2.31	$30,094,000	6,950,000	1.73%	15,914,000	-513,300	1.483	N/A
	BSX	Boston Scientific Corp	23	-	$106.53	$27,944,000	277,000	1.6%	-13,143,000	-183,000	0.019	Medical Instruments &...
	AKRO	Akero Therapeutics, Inc.	24	-	$0.00	$27,233,000	672,759	1.56%	901,000	-273,740	0.892	N/A
	DXCM	DexCom Inc	25	-	$86.33	$27,156,000	397,650	1.56%	-297,000	44,650	0.102	Medical Instruments &...
	IRTC	Irhythm Technologies, Inc.	26	-	$154.71	$26,620,000	254,300	1.53%	-9,223,000	-143,200	0.704	N/A
	EVH	Evolent Health, Inc.	27	-	$11.16	$25,528,000	2,695,700	1.46%	2,353,000	635,700	2.039	N/A
	SRRK	Scholar Rock Holding Corp	28	-	$35.81	$24,484,000	761,541	1.41%	-6,495,000	44,759	0.88	N/A
	KYMR	Kymera Therapeutics, Inc.	29	-	$0.00	$21,744,000	794,437	1.25%	-19,859,000	-239,700	1.124	N/A
	EXAS	Exact Sciences Corp	30	-	$53.65	$20,779,000	480,000	1.19%	-4,507,000	30,000	0.259	Biotechnology
	ACHC	Acadia Healthcare Company Inc	31	-	$73.18	$20,651,000	681,100	1.19%	-2,485,000	97,600	0.687	N/A
	GPCR	Structure Therapeutics Inc.	32	-	$21.08	$19,612,000	1,132,979	1.13%	-9,704,000	52,016	1.798	N/A
	SMMT	Summit Therapeutics Inc	33	-	$20.60	$19,194,000	995,000	1.1%	385,000	-59,000	0.142	N/A
	EW	Edwards Lifesciences Corp	34	-	$27.55	$18,482,000	255,000	1.06%	-21,864,000	-290,000	0.041	Medical Appliances & ...
	TARS	Tarsus Pharmaceuticals, Inc.	35	-	$0.00	$18,204,000	354,376	1.04%	12,064,000	243,487	0.8	N/A
	THC	Tenet Healthcare Corp	36	-	$173.63	$17,485,000	130,000	1%	1,176,000	800	0.12	Hospitals
	LEGN	Churchill Cap Corp Iii	37	-	$34.63	$17,404,000	512,932	1%	739,000	800	0.397	N/A
	IMVT	Immunovant Inc	38	-	$0.00	$16,676,000	975,803	0.96%	-5,842,000	66,700	1.121	N/A
	BRKS	Brooks Automation Inc	39	-	$30.59	$16,454,000	475,000	0.94%	-7,296,000	0	0.643	Semiconductor Equipme...
	INSP	Inspire Medical Systems Inc	40	-	$132.41	$15,809,000	99,250	0.91%	-8,290,000	-30,750	0.29	N/A
	FOLD	Amicus Therapeutics Inc	41	-	$10.61	$15,580,000	1,909,362	0.89%	-8,907,000	-690,063	0.561	Biotechnology
	WRBY	Warby Parker Inc.	42	-	$21.89	$15,222,000	835,000	0.87%	-7,051,000	-85,000	0.697	N/A
	MREO	Mereo Biopharma Group plc	43	-	$2.66	$15,040,000	6,684,247	0.86%	-18,557,000	-2,914,923	6.175	N/A
	CLDX	Celldex Therapeutics Inc	44	-	$20.29	$14,750,000	812,653	0.85%	-16,135,000	-409,529	1.101	Diagnostic Substances
	OSCR	Oscar Health, Inc.	45	-	$0.00	$13,766,000	1,050,000	0.79%	-346,000	0	0.435	N/A
	WST	West Pharmaceutical Service...	46	-	$218.87	$13,489,000	60,250	0.77%	-41,787,000	-108,500	0.081	Rubber & Plastics
	VERA	Vera Therapeutics, Inc.	47	-	$0.00	$12,510,000	520,796	0.72%	-8,122,000	32,933	0.95	N/A
	DHR	Danaher Corp	48	New	$198.80	$12,054,000	58,800	0.69%	12,054,000	58,800	0.008	General Building Mate...
	NAMS	Newamsterdam Pharma Ord Shs	49	-	$0.00	$10,974,000	536,111	0.63%	-8,751,000	-231,411	0.657	N/A
	SRPT	Sarepta Therapeutics Inc	50	-	$17.11	$10,167,000	159,300	0.58%	-27,222,000	-148,200	0.167	Drug Manufacturers - ...
	AGIO	Agios Pharmaceuticals Inc	51	-	$33.47	$10,026,000	342,180	0.58%	-5,454,000	-128,906	0.495	N/A
	PHVS	Pharvaris N V Ord Shs	52	-	$0.00	$9,787,000	623,402	0.56%	-5,072,000	-151,729	0.151	N/A
	CMPX	Compass Therapeutics Ord Shs	53	-	$0.00	$9,430,000	4,962,955	0.54%	1,050,000	-816,620	3.589	N/A
	ELVN	Enliven Therapeutics Ord Shs	54	-	$0.00	$9,168,000	465,871	0.53%	-475,000	37,300	0.927	N/A
	SLNO	Soleno Therapeutics Inc	55	-	$0.16	$8,867,000	124,095	0.51%	3,289,000	0	0.156	N/A
	ARDX	Ardelyx Inc	56	-	$3.69	$7,880,000	1,604,975	0.45%	459,000	141,346	0.691	N/A
	ACRS	Aclaris Therapeutics, Inc.	57	-	$1.47	$7,721,000	5,046,309	0.44%	-7,666,000	-1,158,000	6.815	N/A
	ZBIO	Zenas Biopharma, Inc.	58	-	$9.58	$6,941,000	878,667	0.4%	-255,000	0	2.103	N/A
	ETNB	89bio, Inc.	59	-	$9.86	$6,139,000	844,441	0.35%	1,817,000	291,700	0.797	N/A
	PRTA	Prothena Corp Plc	60	-	$6.08	$6,096,000	492,601	0.35%	-2,832,000	-152,000	0.917	N/A
	JANX	Janux Therapeutics, Inc.	61	-	$0.00	$5,521,000	204,466	0.32%	-5,426,000	0	0.392	N/A
	DYN	Dyne Therapeutics, Inc.	62	-	$9.57	$5,486,000	524,499	0.31%	-5,694,000	49,971	0.455	N/A
	MLYS	Mineralys Therapeutics, Inc.	63	New	$0.00	$5,095,000	320,813	0.29%	5,095,000	320,813	0.645	N/A
	CGEM	Cullinan Oncology Ord Shs	64	-	$0.00	$4,880,000	644,633	0.28%	-4,159,000	-97,481	0.148	N/A
	NVRO	Nevro Corp	65	-	$5.84	$4,675,000	800,494	0.27%	-1,456,000	-847,606	2.006	N/A
	BCAX	Bicara Therapeutics Inc.	66	-	$8.71	$4,379,000	336,070	0.25%	-3,390,000	-109,905	0.618	N/A
	NVAX	Novavax Inc	67	-	$0.36	$4,167,000	650,000	0.24%	-1,059,000	0	0.547	Biotechnology
	KMTS	Kestra Medical Technologies...	68	New	$17.67	$3,613,000	145,000	0.21%	3,613,000	145,000	0.282	N/A
	GOSS	Gossamer Bio Inc	69	-	$1.25	$3,594,000	3,266,960	0.21%	639,000	0	1.449	N/A
	LUNG	Pulmonx Corp	70	-	$0.00	$3,390,000	503,700	0.19%	-1,853,000	-268,451	1.342	N/A
	INZY	Inozyme Pharma, Inc.	71	-	$0.00	$3,135,000	3,445,299	0.18%	-7,563,000	-416,684	5.579	N/A
	BEAM	Beam Therapeutics Inc.	72	-	$16.80	$2,930,000	150,020	0.17%	-3,325,000	-102,203	0.184	N/A
	ATEC	Alphatec Holdings, Inc.	73	-	$11.08	$2,712,000	267,500	0.16%	876,000	67,500	0.269	Medical Instruments &...
	SGMT	Sagimet Biosciences Inc.	74	-	$7.87	$2,568,000	787,808	0.15%	-977,000	0	3.688	N/A
	EDAP	EDAP TMS S.A. (ADR)	75	-	$1.67	$2,489,000	1,270,000	0.14%	-1,029,000	-321,800	4.358	Medical Appliances & ...
	JSPR	Jasper Therapeutics Ord Shs	76	-	$15.12	$2,344,000	545,171	0.13%	-7,557,000	82,083	0.537	N/A
	LENZ	Lenz Therapeutics	77	-	$30.18	$2,136,000	83,082	0.12%	1,290,000	53,777	0.325	N/A
	REGN	Regeneron Pharmaceuticals Inc	78	New	$521.00	$1,776,000	2,800	0.1%	1,776,000	2,800	0.003	Biotechnology
	APLS	Apellis Pharmaceuticals Inc	79	-	$17.43	$1,750,000	80,000	0.1%	-803,000	0	0.065	N/A
	BCRX	Biocryst Pharmaceuticals Inc	80	-	$9.36	$1,665,000	222,011	0.1%	-18,474,000	-2,455,985	0.117	Biotechnology
	MGNX	Macrogenics Inc	81	-	$1.19	$1,454,000	1,145,214	0.08%	-1,970,000	91,567	1.846	Biotechnology
	CGEN	Compugen Ltd (USA)	82	-	$1.66	$1,445,000	989,990	0.08%	-70,000	0	1.195	Biotechnology
	MRSN	Mersana Therapeutics, Inc.	83	-	$0.29	$1,313,000	3,814,684	0.08%	-3,594,000	383,000	3.164	N/A
	NGNE	Neurogene	84	-	$3.68	$1,222,000	104,339	0.07%	-959,000	8,932	0.249	N/A
	AMLX	Amylyx Pharmaceuticals, Inc.	85	New	$0.00	$1,215,000	343,228	0.07%	1,215,000	343,228	0.508	N/A
	SION	Sionna Therapeutics, Inc.	86	New	$0.00	$1,040,000	99,429	0.06%	1,040,000	99,429	0.226	N/A
	APLT	Applied Therapeutics Inc.	87	-	$0.00	$1,014,000	2,074,891	0.06%	-627,000	157,700	1.807	N/A
	CATX	Perspective Therapeutics Inc	88	-	$3.76	$947,000	444,383	0.05%	-471,000	0	0.663	Medical Instruments &...
	VIGL	Vigil Neuroscience, Inc.	89	-	$0.00	$840,000	471,958	0.05%	38,000	0	1.669	N/A
	PLRX	Pliant Therapeutics, Inc.	90	-	$0.00	$796,000	589,996	0.05%	-4,535,000	185,200	0.858	N/A
	SPRB	Spruce Biosciences, Inc.	91	-	$0.00	$757,000	2,609,125	0.04%	-339,000	0	6.984	N/A
	KRRO	Korro Bio	92	-	$0.00	$622,000	35,719	0.04%	-738,000	0	0.106	N/A
	ADAP	Adaptimmune Therapeutics PLC	93	-	$0.25	$489,000	2,483,468	0.03%	-849,000	0	1.606	N/A
	ACRX	Acelrx Pharmaceuticals Inc	94	-	$0.47	$157,000	316,460	0.01%	-9,000	0	3.859	Conglomerates
	NUVB.WS	Nuvation Equity Warrants Ex...	95	-	$0.00	$32,000	134,028	0%	1,000	0	1.489	N/A
	KYTX	Kyverna Therapeutics	111	Closed	$3.28	$0	0	0%	-669,000	-178,963	0	N/A
	CRNX	Crinetics Pharmaceuticals, ...	101	Closed	$29.96	$0	0	0%	-15,037,000	-294,100	0	N/A
	BHVN	Biohaven Ltd.	106	Closed	$14.09	$0	0	0%	-4,850,000	-129,858	0	N/A
	XNCR	Xencor Inc	110	Closed	$8.14	$0	0	0%	-9,215,000	-401,013	0	Biotechnology
	AUTL	Autolus Therapeutics Plc	105	Closed	$2.31	$0	0	0%	-2,428,000	-1,032,988	0	N/A
	LPTX	Leap Therapeutics, Inc.	109	Closed	$0.26	$0	0	0%	-3,641,000	-1,266,546	0	N/A

100 Records Found

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