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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
BPMC |
Blueprint Medicines Corp |
1 |
- |
$93.00 |
$265,796,000 |
2,881,567 |
6.58% |
130,941,000 |
196,273 |
4.366 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
2 |
- |
$58.46 |
$181,834,000 |
2,661,507 |
4.5% |
29,055,000 |
-282,203 |
6.078 |
N/A |
|
|
KRTX |
Karuna Therapeutics, Inc. |
3 |
- |
$0.00 |
$163,010,000 |
515,024 |
4.03% |
77,546,000 |
9,591 |
1.279 |
N/A |
|
|
NBIX |
Neurocrine Biosciences Inc |
4 |
- |
$135.99 |
$157,585,000 |
1,196,000 |
3.9% |
18,535,000 |
-40,000 |
1.28 |
Biotechnology |
|
|
HUM |
Humana Inc |
5 |
- |
$305.90 |
$141,921,000 |
310,000 |
3.51% |
-70,445,000 |
-126,500 |
0.234 |
Health Care Plans |
|
|
PEN |
Penumbra Inc |
6 |
- |
$204.41 |
$135,203,000 |
537,500 |
3.34% |
13,341,000 |
33,750 |
1.48 |
N/A |
|
|
EVH |
Evolent Health, Inc. |
7 |
- |
$27.65 |
$130,799,000 |
3,960,000 |
3.24% |
25,555,000 |
95,000 |
3.39 |
N/A |
|
|
UNH |
Unitedhealth Group Inc |
8 |
- |
$495.35 |
$121,088,000 |
230,000 |
3% |
5,124,000 |
0 |
0.024 |
Health Care Plans |
|
|
CERE |
Cerevel Therapeutics Holdin... |
9 |
- |
$42.47 |
$113,388,000 |
2,674,245 |
2.81% |
58,177,000 |
145,129 |
1.711 |
N/A |
|
|
AGL |
Agilon Health, Inc. |
10 |
- |
$5.00 |
$108,307,000 |
8,630,000 |
2.68% |
-38,968,000 |
337,500 |
1.841 |
N/A |
|
|
ISRG |
Intuitive Surgical Inc |
11 |
- |
$372.63 |
$100,702,000 |
298,500 |
2.49% |
13,453,000 |
0 |
0.083 |
Medical Appliances & ... |
|
|
IDXX |
Idexx Laboratories Inc |
12 |
- |
$499.30 |
$99,493,000 |
179,250 |
2.46% |
14,444,000 |
-15,250 |
0.21 |
Diagnostic Substances |
|
|
PODD |
Insulet Corp |
13 |
- |
$166.19 |
$93,681,000 |
431,750 |
2.32% |
33,075,000 |
51,750 |
0.567 |
Medical Instruments &... |
|
|
ARGX |
Argenx Se |
14 |
- |
$372.80 |
$87,214,000 |
229,250 |
2.16% |
-40,118,000 |
-29,750 |
0.488 |
N/A |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
15 |
- |
$44.24 |
$83,878,000 |
1,754,038 |
2.08% |
31,243,000 |
277,597 |
2.573 |
Restaurants |
|
|
ACHC |
Acadia Healthcare Company Inc |
16 |
- |
$73.18 |
$83,475,000 |
1,073,500 |
2.07% |
19,634,000 |
165,500 |
1.083 |
N/A |
|
|
EXAS |
Exact Sciences Corp |
17 |
- |
$58.85 |
$75,423,000 |
1,019,500 |
1.87% |
5,958,000 |
1,250 |
0.574 |
Biotechnology |
|
|
DXCM |
DexCom Inc |
18 |
- |
$124.34 |
$73,958,000 |
596,000 |
1.83% |
19,471,000 |
12,000 |
0.153 |
Medical Instruments &... |
|
|
BSX |
Boston Scientific Corp |
19 |
- |
$73.17 |
$71,251,000 |
1,232,500 |
1.76% |
10,003,000 |
72,500 |
0.086 |
Medical Instruments &... |
|
|
RYTM |
Rhythm Pharmaceuticals, Inc. |
20 |
- |
$38.28 |
$70,007,000 |
1,522,893 |
1.73% |
33,393,000 |
-74,230 |
2.482 |
N/A |
|
|
ALGN |
Align Technology Inc |
21 |
- |
$309.02 |
$60,280,000 |
220,000 |
1.49% |
-5,974,000 |
3,000 |
0.279 |
Medical Appliances & ... |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
22 |
- |
$0.00 |
$57,832,000 |
1,255,577 |
1.43% |
17,591,000 |
77,575 |
2.008 |
N/A |
|
|
FRPT |
Freshpet, Inc. |
23 |
- |
$106.36 |
$57,479,000 |
662,500 |
1.42% |
13,833,000 |
0 |
1.079 |
N/A |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
24 |
- |
$0.00 |
$54,655,000 |
1,851,464 |
1.35% |
-2,880,000 |
30,731 |
5.022 |
N/A |
|
|
EW |
Edwards Lifesciences Corp |
26 |
- |
$29.43 |
$49,357,000 |
647,300 |
1.22% |
4,512,000 |
0 |
0.104 |
Medical Appliances & ... |
|
|
MRTX |
Mirati Therapeutics, Inc. |
27 |
- |
$58.70 |
$49,102,000 |
835,776 |
1.21% |
-173,000 |
-295,431 |
1.249 |
Biotechnology |
|
|
WST |
West Pharmaceutical Service... |
28 |
- |
$360.43 |
$48,328,000 |
137,250 |
1.2% |
-27,464,000 |
-64,750 |
0.186 |
Rubber & Plastics |
|
|
AGIO |
Agios Pharmaceuticals Inc |
29 |
- |
$31.49 |
$47,929,000 |
2,152,173 |
1.19% |
-19,145,000 |
-557,888 |
3.114 |
N/A |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
30 |
- |
$193.33 |
$45,852,000 |
198,169 |
1.13% |
17,174,000 |
1,800 |
1.195 |
Diagnostic Substances |
|
|
ALNY |
Alnylam Pharmaceuticals Inc |
31 |
- |
$143.31 |
$44,981,000 |
235,000 |
1.11% |
-4,518,000 |
-44,500 |
0.191 |
Biotechnology |
|
|
OLK |
Olink Holding Ab Publ Adr |
32 |
- |
$0.00 |
$42,164,000 |
1,676,500 |
1.04% |
17,436,000 |
0 |
1.409 |
N/A |
|
|
ACCD |
Accolade, Inc. |
33 |
- |
$7.89 |
$41,855,000 |
3,485,000 |
1.04% |
11,035,000 |
572,000 |
4.894 |
N/A |
|
|
IMVT |
Immunovant Inc |
34 |
- |
$0.00 |
$41,426,000 |
983,301 |
1.02% |
16,690,000 |
338,957 |
1.129 |
N/A |
|
|
LLY |
Eli Lilly & Co |
35 |
New |
$733.51 |
$40,513,000 |
69,500 |
1% |
40,513,000 |
69,500 |
0.007 |
Drug Manufacturers - ... |
|
|
KYMR |
Kymera Therapeutics, Inc. |
36 |
- |
$0.00 |
$38,756,000 |
1,522,238 |
0.96% |
17,846,000 |
17,887 |
2.535 |
N/A |
|
|
CLDX |
Celldex Therapeutics Inc |
37 |
- |
$36.30 |
$38,456,000 |
969,646 |
0.95% |
24,693,000 |
469,545 |
1.852 |
Diagnostic Substances |
|
|
IRTC |
Irhythm Technologies, Inc. |
38 |
- |
$111.91 |
$37,544,000 |
350,750 |
0.93% |
4,482,000 |
0 |
0.999 |
N/A |
|
|
ASND |
Ascendis Pharma AS |
39 |
- |
$135.90 |
$36,526,000 |
290,000 |
0.9% |
-3,318,000 |
-135,500 |
0.449 |
N/A |
|
|
PCRX |
Pacira Pharmaceuticals, Inc. |
40 |
- |
$26.33 |
$35,613,000 |
1,055,500 |
0.88% |
3,230,000 |
0 |
2.134 |
Drug Manufacturers - ... |
|
|
LFST |
Lifestance Health Group, Inc. |
41 |
- |
$6.20 |
$35,509,000 |
4,535,000 |
0.88% |
10,296,000 |
865,000 |
1.214 |
N/A |
|
|
BRKS |
Brooks Automation Inc |
42 |
- |
$52.18 |
$33,059,000 |
507,500 |
0.82% |
9,093,000 |
30,000 |
0.687 |
Semiconductor Equipme... |
|
|
SRPT |
Sarepta Therapeutics Inc |
43 |
- |
$128.77 |
$31,590,000 |
327,600 |
0.78% |
-15,928,000 |
-64,400 |
0.389 |
Drug Manufacturers - ... |
|
|
ZLAB |
Zai Lab Ltd |
44 |
- |
$15.91 |
$31,075,000 |
1,137,023 |
0.77% |
1,003,000 |
-100,000 |
1.292 |
N/A |
|
|
LEGN |
Churchill Cap Corp Iii |
45 |
- |
$45.30 |
$29,630,000 |
492,444 |
0.73% |
-1,152,000 |
34,179 |
0.381 |
N/A |
|
|
WRBY |
Warby Parker Inc. |
46 |
- |
$12.92 |
$28,599,000 |
2,028,300 |
0.71% |
7,872,000 |
453,300 |
2.114 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
47 |
- |
$0.00 |
$25,243,000 |
1,081,064 |
0.62% |
-46,538,000 |
-338,086 |
2.152 |
N/A |
|
|
TVTX |
Travere Therapeutics, Inc |
48 |
- |
$5.26 |
$24,915,000 |
2,771,446 |
0.62% |
8,754,000 |
963,704 |
3.163 |
N/A |
|
|
MRUS |
Merus Nv |
49 |
- |
$45.04 |
$23,982,000 |
872,069 |
0.59% |
4,212,000 |
33,641 |
2.044 |
N/A |
|
|
DVAX |
Dynavax Technologies Corp |
50 |
- |
$11.21 |
$23,423,000 |
1,675,474 |
0.58% |
-3,366,000 |
-138,284 |
1.243 |
Drug Manufacturers - ... |
|
|
SWAV |
Shockwave Medical, Inc. |
51 |
- |
$330.00 |
$22,867,000 |
120,000 |
0.57% |
-6,500,000 |
-27,500 |
0.35 |
N/A |
|
|
PRTA |
Prothena Corp Plc |
52 |
- |
$20.87 |
$22,714,000 |
625,048 |
0.56% |
-6,926,000 |
10,750 |
1.211 |
N/A |
|
|
IMGN |
Immunogen Inc |
53 |
- |
$31.23 |
$22,515,000 |
759,365 |
0.56% |
10,464,000 |
0 |
0.344 |
Drug Manufacturers - ... |
|
|
NVRO |
Nevro Corp |
54 |
- |
$11.32 |
$22,058,000 |
1,025,000 |
0.55% |
-1,229,000 |
-186,600 |
2.76 |
N/A |
|
|
AMGN |
Amgen Inc |
55 |
- |
$269.98 |
$21,457,000 |
74,500 |
0.53% |
3,181,000 |
6,500 |
0.013 |
Biotechnology |
|
|
IRON |
Disc Medicine, Inc |
56 |
- |
$27.55 |
$20,994,000 |
363,468 |
0.52% |
3,918,000 |
0 |
2.088 |
N/A |
|
|
RVMD |
Revolution Medicines, Inc. |
57 |
- |
$35.96 |
$20,797,000 |
725,152 |
0.51% |
725,000 |
0 |
0.633 |
N/A |
|
|
INSP |
Inspire Medical Systems Inc |
58 |
- |
$237.45 |
$20,140,000 |
99,000 |
0.5% |
11,309,000 |
54,500 |
0.344 |
N/A |
|
|
IMTX |
Immatics N.V |
59 |
- |
$10.01 |
$19,749,000 |
1,875,466 |
0.49% |
-1,969,000 |
0 |
2.981 |
N/A |
|
|
BCRX |
Biocryst Pharmaceuticals Inc |
60 |
- |
$4.16 |
$19,590,000 |
3,270,381 |
0.48% |
1,527,000 |
719,155 |
1.852 |
Biotechnology |
|
|
MREO |
Mereo Biopharma Group plc |
61 |
- |
$2.74 |
$18,443,000 |
7,983,851 |
0.46% |
8,540,000 |
307,370 |
7.375 |
N/A |
|
|
COLL |
Collegium Pharmaceutical, Inc |
62 |
- |
$36.42 |
$17,298,000 |
562,000 |
0.43% |
4,737,000 |
0 |
1.354 |
N/A |
|
|
INZY |
Inozyme Pharma, Inc. |
63 |
- |
$0.00 |
$15,682,000 |
3,681,174 |
0.39% |
221,000 |
0 |
5.961 |
N/A |
|
|
FOLD |
Amicus Therapeutics Inc |
64 |
- |
$10.61 |
$15,095,000 |
1,063,806 |
0.37% |
2,159,000 |
0 |
0.313 |
Biotechnology |
|
|
BMRN |
Biomarin Pharmaceutical Inc |
65 |
- |
$88.63 |
$14,350,000 |
148,832 |
0.36% |
-9,053,000 |
-115,668 |
0.079 |
Drug Manufacturers - ... |
|
|
ICVX |
Icosavax, Inc. |
66 |
- |
$0.00 |
$13,686,000 |
868,409 |
0.34% |
6,956,000 |
0 |
2.205 |
N/A |
|
|
KRYS |
Krystal Biotech Inc |
67 |
- |
$156.88 |
$12,898,000 |
103,969 |
0.32% |
2,393,000 |
13,409 |
0.417 |
N/A |
|
|
GPCR |
Structure Therapeutics Inc. |
68 |
New |
$38.94 |
$11,685,000 |
286,676 |
0.29% |
11,685,000 |
286,676 |
0.749 |
N/A |
|
|
MGNX |
Macrogenics Inc |
69 |
- |
$14.56 |
$11,340,000 |
1,178,796 |
0.28% |
5,847,000 |
0 |
1.918 |
Biotechnology |
|
|
MLYS |
Mineralys Therapeutics, Inc. |
70 |
- |
$0.00 |
$10,040,000 |
1,167,492 |
0.25% |
-1,063,000 |
0 |
2.857 |
N/A |
|
|
ABOS |
Acumen Pharmaceuticals, Inc. |
71 |
- |
$0.00 |
$8,832,000 |
2,300,059 |
0.22% |
-2,840,000 |
-512,520 |
5.683 |
N/A |
|
|
CMPX |
Compass Therapeutics Ord Shs |
72 |
- |
$0.00 |
$8,602,000 |
5,513,788 |
0.21% |
-2,260,000 |
0 |
5.625 |
N/A |
|
|
LUNG |
Pulmonx Corp |
73 |
- |
$0.00 |
$8,318,000 |
652,400 |
0.21% |
1,579,000 |
0 |
1.738 |
N/A |
|
|
AMLX |
Amylyx Pharmaceuticals, Inc. |
74 |
- |
$0.00 |
$7,875,000 |
535,012 |
0.19% |
-20,414,000 |
-1,010,004 |
0.925 |
N/A |
|
|
SPRB |
Spruce Biosciences, Inc. |
75 |
- |
$0.00 |
$7,645,000 |
2,609,125 |
0.19% |
1,479,000 |
-119,000 |
6.984 |
N/A |
|
|
RLAY |
Relay Therapeutics, Inc. |
76 |
- |
$6.37 |
$7,420,000 |
673,966 |
0.18% |
1,752,000 |
0 |
0.498 |
N/A |
|
|
EDAP |
EDAP TMS S.A. (ADR) |
77 |
- |
$7.28 |
$7,320,000 |
1,386,425 |
0.18% |
-2,227,000 |
26,425 |
4.758 |
Medical Appliances & ... |
|
|
MRSN |
Mersana Therapeutics, Inc. |
78 |
- |
$2.94 |
$7,069,000 |
3,046,782 |
0.17% |
2,747,000 |
-356,351 |
2.718 |
N/A |
|
|
PLRX |
Pliant Therapeutics, Inc. |
79 |
- |
$0.00 |
$6,972,000 |
384,996 |
0.17% |
-1,546,000 |
-106,225 |
0.612 |
N/A |
|
|
OSCR |
Oscar Health, Inc. |
80 |
New |
$0.00 |
$6,725,000 |
735,000 |
0.17% |
6,725,000 |
735,000 |
0.437 |
N/A |
|
|
FULC |
Fulcrum Therapeutics, Inc. |
81 |
- |
$0.00 |
$4,912,000 |
727,673 |
0.12% |
1,681,000 |
0 |
1.155 |
N/A |
|
|
EPIX |
ESSA Pharma Inc |
82 |
- |
$0.00 |
$4,468,000 |
677,005 |
0.11% |
2,376,000 |
0 |
1.539 |
Diagnostic Substances |
|
|
SGMT |
Sagimet Biosciences Inc. |
83 |
- |
$4.06 |
$4,002,000 |
738,355 |
0.1% |
-2,496,000 |
0 |
3.457 |
N/A |
|
|
AUPH |
Aurinia Pharmaceuticals Inc |
84 |
- |
$4.91 |
$3,709,000 |
412,570 |
0.09% |
-17,000 |
-66,970 |
0.326 |
N/A |
|
|
LPTX |
Leap Therapeutics, Inc. |
85 |
- |
$3.25 |
$3,453,000 |
832,937 |
0.09% |
1,970,000 |
-241,580 |
1.396 |
N/A |
|
|
ACRS |
Aclaris Therapeutics, Inc. |
86 |
- |
$1.20 |
$3,148,000 |
2,998,495 |
0.08% |
-23,981,000 |
-961,954 |
4.05 |
N/A |
|
|
BEAM |
Beam Therapeutics Inc. |
87 |
- |
$21.38 |
$3,033,000 |
111,430 |
0.08% |
353,000 |
0 |
0.177 |
N/A |
|
|
APLT |
Applied Therapeutics Inc. |
88 |
- |
$0.00 |
$2,999,000 |
895,195 |
0.07% |
985,000 |
86,386 |
1.865 |
N/A |
|
|
GOSS |
Gossamer Bio Inc |
89 |
- |
$0.67 |
$2,981,000 |
3,266,960 |
0.07% |
260,000 |
0 |
3.458 |
N/A |
|
|
BMEA |
Biomea Fusion, Inc. |
90 |
- |
$10.78 |
$2,630,000 |
181,147 |
0.07% |
137,000 |
0 |
0.63 |
N/A |
|
|
NVAX |
Novavax Inc |
91 |
- |
$0.36 |
$2,581,000 |
537,625 |
0.06% |
-2,108,000 |
-110,075 |
0.453 |
Biotechnology |
|
|
CGEN |
Compugen Ltd (USA) |
92 |
- |
$1.92 |
$2,554,000 |
1,289,990 |
0.06% |
1,354,000 |
0 |
1.557 |
Biotechnology |
|
|
ADAP |
Adaptimmune Therapeutics PLC |
93 |
- |
$1.08 |
$1,923,000 |
2,425,468 |
0.05% |
-252,000 |
-362,377 |
1.568 |
N/A |
|
|
VIGL |
Vigil Neuroscience, Inc. |
94 |
- |
$0.00 |
$1,595,000 |
471,958 |
0.04% |
-949,000 |
0 |
1.669 |
N/A |
|
|
RPHM |
Reneo Pharmaceuticals, Inc. |
95 |
- |
$1.67 |
$1,203,000 |
751,730 |
0.03% |
-7,502,000 |
-391,455 |
3.095 |
N/A |
|
|
VINC |
Vincerx Pharma, Inc |
96 |
- |
$0.73 |
$1,052,000 |
891,719 |
0.03% |
151,000 |
0 |
4.242 |
N/A |
|
|
XLO |
Xilio Therapeutics, Inc. |
97 |
- |
$0.00 |
$792,000 |
1,440,759 |
0.02% |
-2,248,000 |
0 |
5.402 |
N/A |
|
|
ACRX |
Acelrx Pharmaceuticals Inc |
98 |
- |
$1.05 |
$233,000 |
316,460 |
0.01% |
49,000 |
0 |
3.859 |
Conglomerates |
|
|
NUVB.WS |
Nuvation Equity Warrants Ex... |
99 |
- |
$0.00 |
$8,000 |
134,028 |
0% |
-5,000 |
0 |
1.489 |
N/A |
|
|
GMDA |
Gamida Cell Ord Shs |
118 |
Closed |
$0.00 |
$0 |
0 |
0% |
-54,000 |
-52,015 |
0 |
N/A |
|
|
HZNP |
Horizon Pharma, Inc. |
105 |
Closed |
$28.30 |
$0 |
0 |
0% |
-29,559,000 |
-255,500 |
0 |
Drug Manufacturers - ... |
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