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| Name: |
RTW INVESTMENTS LLC |
| City: |
NEW YORK |
| State: |
NY |
| Zip: |
10019 |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
RCKT |
Rocket Pharmaceuticals |
1 |
- |
$21.98 |
$530,103,000 |
17,687,772 |
8.28% |
167,681,000 |
0 |
22.466 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
2 |
- |
$58.46 |
$416,505,000 |
6,096,387 |
6.51% |
100,103,000 |
0 |
13.922 |
N/A |
|
|
MRTX |
Mirati Therapeutics, Inc. |
3 |
- |
$58.70 |
$397,650,000 |
6,768,514 |
6.21% |
102,814,000 |
0 |
10.112 |
Biotechnology |
|
|
AXSM |
Axsome Therapeutics, Inc. |
4 |
- |
$71.71 |
$357,327,000 |
4,489,596 |
5.58% |
43,549,000 |
0 |
12.024 |
N/A |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
5 |
- |
$16.71 |
$352,349,000 |
11,253,551 |
5.5% |
111,094,000 |
-322,986 |
7 |
Biotechnology |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
6 |
- |
$44.24 |
$329,340,000 |
6,887,086 |
5.14% |
136,649,000 |
1,481,997 |
10.104 |
Restaurants |
|
|
ALNY |
Alnylam Pharmaceuticals Inc |
7 |
- |
$143.31 |
$314,019,000 |
1,640,559 |
4.91% |
15,896,000 |
-42,803 |
1.333 |
Biotechnology |
|
|
ARGX |
Argenx Se |
8 |
- |
$372.80 |
$253,821,000 |
667,195 |
3.96% |
4,469,000 |
160,000 |
1.419 |
N/A |
|
|
BRKR |
Bruker Corp |
9 |
- |
$80.97 |
$245,724,000 |
3,344,095 |
3.84% |
35,044,000 |
-37,608 |
2.184 |
Scientific & Technica... |
|
|
CYTK |
Cytokinetics Inc |
10 |
- |
$65.34 |
$210,819,000 |
2,525,080 |
3.29% |
134,983,000 |
-49,118 |
2.232 |
Biotechnology |
|
|
PTCT |
PTC Therapeutics, Inc. |
11 |
- |
$28.57 |
$204,605,000 |
7,423,970 |
3.2% |
42,464,000 |
188,774 |
9.056 |
Biotechnology |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
12 |
- |
$193.33 |
$188,619,000 |
815,191 |
2.95% |
143,422,000 |
505,706 |
4.917 |
Diagnostic Substances |
|
|
ARVN |
Arvinas Holding Company, Llc |
13 |
New |
$32.37 |
$173,427,000 |
4,213,483 |
2.71% |
173,427,000 |
4,213,483 |
7.919 |
N/A |
|
|
MASI |
Masimo Corp |
14 |
- |
$136.14 |
$171,408,000 |
1,462,400 |
2.68% |
39,757,000 |
-39,093 |
2.656 |
Medical Appliances & ... |
|
|
PEN |
Penumbra Inc |
15 |
- |
$204.41 |
$166,687,000 |
662,664 |
2.6% |
3,792,000 |
-10,707 |
1.825 |
N/A |
|
|
NTRA |
Natera, Inc. |
16 |
- |
$91.66 |
$162,446,000 |
2,593,323 |
2.54% |
45,105,000 |
-58,460 |
2.379 |
N/A |
|
|
CLDX |
Celldex Therapeutics Inc |
17 |
- |
$36.30 |
$137,351,000 |
3,463,201 |
2.15% |
42,044,000 |
0 |
6.614 |
Diagnostic Substances |
|
|
PTGX |
Protagonist Therapeutics, Inc |
18 |
- |
$25.15 |
$121,885,000 |
5,315,514 |
1.9% |
31,554,000 |
-100,000 |
9.456 |
N/A |
|
|
CRGX |
Cargo Therapeutics, Inc. |
19 |
New |
$0.00 |
$119,821,000 |
5,175,832 |
1.87% |
119,821,000 |
5,175,832 |
0 |
N/A |
|
|
VCEL |
Vericel Corp |
20 |
- |
$46.05 |
$114,408,000 |
3,212,794 |
1.79% |
4,064,000 |
-79,079 |
6.134 |
Medical Laboratories ... |
|
|
SAGE |
Sage Therapeutics, Inc. |
21 |
- |
$0.00 |
$112,619,000 |
5,197,019 |
1.76% |
6,643,000 |
47,537 |
8.916 |
N/A |
|
|
ALKS |
Alkermes Plc |
22 |
- |
$24.68 |
$108,228,000 |
3,901,523 |
1.69% |
83,325,000 |
3,012,450 |
2.373 |
Drug Delivery |
|
|
AVDL |
AVADEL Pharmaceuticals Plc |
23 |
- |
$15.99 |
$98,105,000 |
6,947,918 |
1.53% |
24,600,000 |
-188,497 |
11.93 |
Drug Delivery |
|
|
TXG |
10x Genomics, Inc. |
24 |
- |
$0.00 |
$86,735,000 |
1,549,951 |
1.35% |
24,037,000 |
29,995 |
1.692 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
25 |
New |
$0.00 |
$83,891,000 |
3,592,759 |
1.31% |
83,891,000 |
3,592,759 |
7.153 |
N/A |
|
|
MRUS |
Merus Nv |
26 |
- |
$45.04 |
$65,275,000 |
2,373,625 |
1.02% |
18,191,000 |
376,861 |
5.563 |
N/A |
|
|
ESTA |
Establishment Labs Holdings... |
27 |
- |
$48.47 |
$64,573,000 |
2,494,138 |
1.01% |
-57,814,000 |
0 |
10.641 |
N/A |
|
|
TARS |
Tarsus Pharmaceuticals, Inc. |
28 |
- |
$0.00 |
$63,835,000 |
3,152,341 |
1% |
12,645,000 |
271,640 |
11.82 |
N/A |
|
|
ETNB |
89bio, Inc. |
29 |
New |
$8.26 |
$62,317,000 |
5,578,931 |
0.97% |
62,317,000 |
5,578,931 |
7.488 |
N/A |
|
|
RNA |
Avidity Biosciences, Inc. |
30 |
- |
$24.36 |
$60,543,000 |
6,689,789 |
0.95% |
17,862,000 |
0 |
8.414 |
N/A |
|
|
APGE |
Apogee Therapeutics, Inc. |
31 |
- |
$47.13 |
$59,864,000 |
2,142,591 |
0.94% |
14,227,000 |
0 |
5.761 |
N/A |
|
|
INSM |
Insmed Inc |
32 |
- |
$24.80 |
$57,800,000 |
1,865,108 |
0.9% |
10,706,000 |
0 |
1.231 |
Biotechnology |
|
|
OBIO |
Orchestra BioMed Holdings Inc. |
33 |
- |
$4.39 |
$51,316,000 |
5,620,640 |
0.8% |
2,304,000 |
0 |
15.725 |
N/A |
|
|
AGLE |
Aeglea Biotherapeutics, Inc. |
34 |
New |
$0.60 |
$48,049,000 |
2,232,760 |
0.75% |
48,049,000 |
2,232,760 |
3.65 |
N/A |
|
|
FULC |
Fulcrum Therapeutics, Inc. |
35 |
- |
$0.00 |
$36,922,000 |
5,469,956 |
0.58% |
11,087,000 |
-348,848 |
8.678 |
N/A |
|
|
TSHA |
Taysha Gene Therapies, Inc. |
36 |
- |
$0.00 |
$29,901,000 |
16,893,185 |
0.47% |
-23,481,000 |
0 |
45.67 |
N/A |
|
|
DHR |
Danaher Corp |
37 |
New |
$246.58 |
$27,433,000 |
118,584 |
0.43% |
27,433,000 |
118,584 |
0.017 |
General Building Mate... |
|
|
TMO |
Thermo Fisher Scientific |
38 |
- |
$573.60 |
$26,540,000 |
50,000 |
0.41% |
-120,418,000 |
-240,334 |
0.013 |
Medical Laboratories ... |
|
|
URGN |
Urogen Pharma Ltd. |
39 |
- |
$14.15 |
$25,902,000 |
1,726,808 |
0.4% |
13,889,000 |
869,344 |
7.817 |
N/A |
|
|
RDNT |
Radnet Inc |
40 |
New |
$48.40 |
$23,073,000 |
663,602 |
0.36% |
23,073,000 |
663,602 |
1.285 |
Specialized Health Se... |
|
|
SWTX |
Springworks Therapeutics, Inc. |
41 |
New |
$0.00 |
$22,813,000 |
625,000 |
0.36% |
22,813,000 |
625,000 |
0.899 |
N/A |
|
|
STOK |
Stoke Therapeutics, Inc. |
42 |
- |
$0.00 |
$21,729,000 |
4,131,045 |
0.34% |
4,430,000 |
-259,513 |
8.681 |
N/A |
|
|
TNGX |
Tango Therapeutics Ord Shs |
43 |
New |
$0.00 |
$19,471,000 |
1,966,752 |
0.3% |
19,471,000 |
1,966,752 |
2.246 |
N/A |
|
|
GHRS |
Gh Research Ord Shs |
44 |
- |
$0.00 |
$19,297,000 |
3,327,129 |
0.3% |
-14,141,000 |
0 |
6.811 |
N/A |
|
|
ROIV |
Roivant Sciences Ltd. |
45 |
- |
$11.03 |
$16,331,000 |
1,454,273 |
0.26% |
-1,805,000 |
-98,444 |
0.21 |
N/A |
|
|
IMTX |
Immatics N.V |
46 |
- |
$10.01 |
$15,636,000 |
1,484,911 |
0.24% |
5,851,000 |
639,911 |
2.36 |
N/A |
|
|
EPIX |
ESSA Pharma Inc |
47 |
New |
$0.00 |
$15,171,000 |
2,298,662 |
0.24% |
15,171,000 |
2,298,662 |
5.227 |
Diagnostic Substances |
|
|
GH |
Guardant Health, Inc. |
48 |
- |
$0.00 |
$13,335,000 |
492,977 |
0.21% |
-1,511,000 |
-7,910 |
0.493 |
N/A |
|
|
VRDN |
Viridian Therapeutics Ors Shs |
49 |
New |
$12.88 |
$13,195,000 |
605,816 |
0.21% |
13,195,000 |
605,816 |
1.336 |
N/A |
|
|
ALUR |
Allurion Technologies, Inc. |
50 |
- |
$1.92 |
$12,932,000 |
3,457,707 |
0.2% |
-1,936,000 |
0 |
0 |
N/A |
|
|
SWAV |
Shockwave Medical, Inc. |
51 |
- |
$330.00 |
$12,398,000 |
65,060 |
0.19% |
-12,290,000 |
-58,940 |
0.19 |
N/A |
|
|
TRML |
Tourmaline Bio |
52 |
New |
$0.00 |
$10,442,000 |
398,850 |
0.16% |
10,442,000 |
398,850 |
0.966 |
N/A |
|
|
ACET |
Adicet Bio, Inc |
53 |
- |
$1.68 |
$7,814,000 |
4,134,631 |
0.12% |
2,003,000 |
-106,841 |
9.649 |
N/A |
|
|
SLRN |
Acelyrin, Inc. |
54 |
- |
$4.24 |
$7,298,000 |
978,310 |
0.11% |
-2,651,000 |
0 |
1.006 |
N/A |
|
|
IMUX |
Immunic Inc |
55 |
- |
$1.22 |
$6,503,000 |
4,335,255 |
0.1% |
130,000 |
0 |
9.773 |
N/A |
|
|
CUTR |
Cutera Inc |
56 |
- |
$2.12 |
$6,407,000 |
1,817,585 |
0.1% |
-4,710,000 |
-29,011 |
6.855 |
Medical Appliances & ... |
|
|
SABS |
Sab Biotherapeutics |
57 |
New |
$5.94 |
$6,310,000 |
9,178,282 |
0.1% |
6,310,000 |
9,178,282 |
21.114 |
N/A |
|
|
MIST |
Milestone Pharmaceuticals Inc. |
58 |
- |
$0.00 |
$5,438,000 |
3,256,102 |
0.08% |
-4,656,000 |
0 |
13.296 |
N/A |
|
|
XGN |
Exagen Inc. |
59 |
- |
$0.00 |
$2,994,000 |
1,504,602 |
0.05% |
-618,000 |
12,170 |
11.894 |
N/A |
|
|
APYX |
Apyx Medical Corp |
60 |
- |
$1.45 |
$2,688,000 |
1,025,963 |
0.04% |
-2,999,000 |
-751,231 |
2.994 |
Medical Instruments &... |
|
|
ARYD |
Arya Sciences Acquisition C... |
61 |
- |
$0.00 |
$1,395,000 |
127,970 |
0.02% |
10,000 |
0 |
0.828 |
N/A |
|
|
SGHT |
Sight Sciences, Inc. |
62 |
New |
$0.00 |
$850,000 |
164,806 |
0.01% |
850,000 |
164,806 |
0.349 |
N/A |
|
|
SIEN |
Sientra, Inc. |
63 |
- |
$0.10 |
$49,000 |
81,016 |
0% |
-796,000 |
-223,020 |
0.08 |
N/A |
|
|
RYZB |
Rayzebio, Inc. |
75 |
Closed |
$62.49 |
$0 |
0 |
0% |
-1,028,000 |
-46,300 |
0 |
N/A |
|
|
ILMN |
Illumina Inc |
78 |
Closed |
$122.28 |
$0 |
0 |
0% |
-25,826,000 |
-188,125 |
0 |
Scientific & Technica... |
|
|
MLTX |
Multisys Language Solutions... |
65 |
Closed |
$0.00 |
$0 |
0 |
0% |
-28,500,000 |
-500,000 |
0 |
N/A |
|
|
SGMT |
Sagimet Biosciences Inc. |
74 |
Closed |
$4.06 |
$0 |
0 |
0% |
-3,522,000 |
-400,277 |
0 |
N/A |
|
|
DMTK |
Dermtech Ord Shs |
77 |
Closed |
$3.09 |
$0 |
0 |
0% |
-3,914,000 |
-2,718,356 |
0 |
N/A |
|
|
MIRO |
Miromatrix Medical Inc. |
64 |
Closed |
$3.39 |
$0 |
0 |
0% |
-583,000 |
-445,222 |
0 |
N/A |
|
|
MLYS |
Mineralys Therapeutics, Inc. |
66 |
Closed |
$0.00 |
$0 |
0 |
0% |
-8,769,000 |
-922,100 |
0 |
N/A |
|
|
RLMD |
Relmada Therapeutics, Inc. |
73 |
Closed |
$3.83 |
$0 |
0 |
0% |
-6,396,000 |
-2,131,835 |
0 |
N/A |
|
|
VKTX |
Viking Therapeutics, Inc. |
70 |
Closed |
$74.31 |
$0 |
0 |
0% |
-2,872,000 |
-259,400 |
0 |
N/A |
|
|
PMVP |
Pmv Pharmaceuticals, Inc. |
72 |
Closed |
$0.00 |
$0 |
0 |
0% |
-14,587,000 |
-2,375,785 |
0 |
N/A |
|
|
OM |
Outset Medical, Inc. |
67 |
Closed |
$2.40 |
$0 |
0 |
0% |
-8,798,000 |
-808,658 |
0 |
N/A |
|
|
AKYA |
Akoya Biosciences, Inc. |
69 |
Closed |
$3.80 |
$0 |
0 |
0% |
-1,574,000 |
-338,422 |
0 |
N/A |
|
|
SYK |
Stryker Corp |
71 |
Closed |
$335.61 |
$0 |
0 |
0% |
-7,652,000 |
-28,000 |
0 |
Medical Instruments &... |
|
|
DSGN |
Design Therapeutics, Inc. |
76 |
Closed |
$0.00 |
$0 |
0 |
0% |
-5,931,000 |
-2,512,986 |
0 |
N/A |
|
|
SCPH |
Scpharmaceuticals Inc. |
68 |
Closed |
$0.00 |
$0 |
0 |
0% |
-23,481,000 |
-3,297,843 |
0 |
N/A |
|
|
AXNX |
Axonics Modulation Technolo... |
79 |
Closed |
$66.69 |
$0 |
0 |
0% |
-24,832,000 |
-442,487 |
0 |
N/A |
|
|
OLK |
Olink Holding Ab Publ Adr |
80 |
Closed |
$0.00 |
$0 |
0 |
0% |
-2,414,000 |
-163,652 |
0 |
N/A |
|
