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Insider Information:   Isaly Samuel D
Relationship:   10% Owner
City:   New York
State:   NY
   
Insider Summary:
  
   
Companies Owned :   36    
Direct Shares   1,096,936    

Indirect Shares

   77,548,174      
Direct Value   $110    

Indirect Value

   $831,936,216      
Total Shares   78,645,110      
Total Value   $831,936,325      


American Cryostem Corporation $110 American Cryostem Corporation $110
 


Historical Performance :
Based on 6 Month Return Percentages
Buys 
Sells 

     Total Filings :
    4   
    0    

     Stock price went up :
    4   
    0    
     Stock price went down :
    0   
    0    
   
     Gain/Loss Ratio :
   4.0   
   0.0   
     Percentage Gain/Loss :
   54.4%
   0.0%
     
   
Holdings :
     Menu Company Name Ticker Relation Direct Date Direct Shares Indirect Date Indirect Shares Total Value Sold  
            American Cryostem Corporation CRYO Director, 10% Owner 2005-07-13 1,096,936 2005-07-13 1,231,936    Premium*  
            Volcano Corp VOLC Director 2006-06-20 0 2006-06-20 195,705    Premium*  
            Aryx Therapeutics Inc ARYX 10% Owner 2007-11-13 0 2009-05-22 1,340,139    Premium*  
            Albireo Pharma Inc ALBO Director 2008-02-12 0 2009-06-10 1,485,904    Premium*  
            Athersys Inc (New) ATHX 10% Owner 2008-05-21 0 2011-04-26 15,250    Premium*  
            Nxstage Medical, Inc. NXTM Director 2010-12-09 0 2010-12-09 2,690,476    Premium*  
            Kun Run Biotechnology Inc KURU 10% Owner 0 2010-04-30 5,228,758    Premium*  
            Anthera Pharmaceuticals Inc ANTH Director 2010-09-30 0 2013-01-30 7,462,000    Premium*  
            Amarin Corp Plc AMRN Director 0 2012-09-04 5,700    Premium*  
            Pacira Pharmaceuticals, Inc. PCRX 10% Owner 0 2012-03-12 2,446,000    Premium*  
            Chemocentryx, Inc. CCXI 10% Owner 2012-02-13 0 2012-02-13 908,509    Premium*  
            Supernus Pharmaceuticals Inc SUPN Director, 10% Owner 2012-05-04 0 2012-05-04 297,815    Premium*  
            Mirati Therapeutics, Inc. MRTX 10% Owner 0 2015-02-03 1,267,000    Premium*  
            Acceleron Pharma Inc XLRN Former 10% Owner 2013-09-24 0 2013-09-24 576,889    Premium*  
            Relypsa Inc RLYP 10% Owner 2013-11-20 0 2016-07-25 3,356,400    Premium*  
            Roka Bioscience, Inc. ROKA 10% Owner 0 2017-10-03 0    Premium*  
            Loxo Oncology, Inc. LOXO Director 2014-08-06 0 2017-12-08 941,000    Premium*  
            Otonomy, Inc. OTIC Director 2014-08-18 0 2015-11-30 1,850,094    Premium*  
            Sientra, Inc. SIEN 10% Owner 0 2015-10-12 17,100    Premium*  
            Pieris Pharmaceuticals, Inc. PIRS 10% Owner 0 2018-01-03 49,270    Premium*  
            Glaukos Corp GKOS Director 2015-06-30 0 2017-09-05 7,895    Premium*  
            Dimension Therapeutics, Inc. DMTX Director, 10% Owner 2015-10-27 0 2015-10-27 5,397,698    Premium*  
            Adaptimmune Therapeutics PLC ADAP Director 0 2017-03-27 6,149,377    Premium*  
            Viewray, Inc. VRAY Director, 10% Owner 0 2017-01-18 89,225    Premium*  
            Aeglea Biotherapeutics, Inc. AGLE 10% Owner 0 2017-02-21 1,469,524    Premium*  
            Intellia Therapeutics, Inc. NTLA Director 2016-05-11 0 2016-05-11 2,662,180    Premium*  
            Corvus Pharmaceuticals, Inc. CRVS Director, 10% Owner 2016-05-18 0 2016-06-24 5,379,349    Premium*  
            Selecta Biosciences Inc SELB Director, 10% Owner 0 2016-06-27 1,825,415    Premium*  
            Steadymed Ltd. STDY 10% Owner 0 2017-04-25 2,123,098    Premium*  
            Nabriva Therapeutics AG NBRV Director, 10% Owner 0 2016-12-30 391,960    Premium*  
            Aadi Bioscience, Inc AADI Director, 10% Owner 2017-03-15 0 2017-03-15 4,416,446    Premium*  
            Cti Biopharma Corporation CTIC 10% Owner 2017-06-13 0 2017-06-13 5,000,000    Premium*  
            Alpine Immune Sciences Inc ALPN Director, 10% Owner 2017-07-24 0 2017-07-24 3,298,516    Premium*  
            Kala Pharmaceuticals, Inc. KALA 10% Owner 2017-07-25 0 2018-01-12 2,692,715    Premium*  
            Scpharmaceuticals Inc. SCPH 10% Owner 2017-11-21 0 2017-11-21 3,409,865    Premium*  
            X4 Pharmaceuticals Inc XFOR 10% Owner 2017-11-20 0 2017-11-20 1,868,966    Premium*  
* Premium Members only  

Records found :    248         Free Registration Required For Full Results.    Limit: 25

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  Page 9 of 10
Ticker Company Name Relation   Off-Dir-10% Trans. Date Form Action Price Mkt Value D/I Shares    Holdings   
Rank

  
3m +/-  
Form
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-09-07 4 S $16.79 $673,279 I/I (40,100) 4,159,700 0 -
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-07-27 4 S $16.93 $9,691,312 I/I (572,556) 5,145,700 0 -
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-08-18 4 S $16.94 $1,697,388 I/I (100,200) 4,199,800 0 -
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-08-17 4 S $17.06 $4,913,280 I/I (288,000) 4,300,000 0 -
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-08-16 4 S $17.11 $1,916,320 I/I (112,000) 4,588,000 0 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2013-10-29 4 B $17.50 $2,187,500 I/I 125,000 1,274,332 1.5 -
GKOS Glaukos Corp Director   –       •       •   2015-06-30 4 D $18.00 $211,212 I/I (11,734) 27,344 0 -
NTLA Intellia Therapeutics, In... Director   –       •      –    2016-05-11 4 B $18.00 $4,500,000 I/I 250,000 2,662,180 2.1 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2015-02-03 4 B $20.00 $2,000,000 I/I 100,000 1,267,000 1.5 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2014-07-01 4 S $20.04 $100,200 I/I (5,000) 1,167,000 0 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2014-06-30 4 S $20.33 $288,299 I/I (14,000) 1,172,000 0 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2014-06-27 4 S $21.79 $1,936,730 I/I (88,332) 1,186,000 0 -
NXTM Nxstage Medical, Inc. Director   –       •      –    2010-12-09 4 S $22.60 $53,255 D/D (2,356) 0 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2014-09-17 4 S $25.07 $1,228,430 I/I (49,000) 8,857,551 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2014-09-16 4 S $25.45 $1,146,836 I/I (45,000) 8,906,551 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2014-08-15 4 S $26.35 $26,086,500 I/I (990,000) 8,951,551 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-12-22 4 S $26.39 $3,982,837 I/I (150,000) 7,500,000 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-12-23 4 S $26.78 $2,717,564 I/I (100,000) 7,400,000 0 -
LOXO Loxo Oncology, Inc. Director   –       •      –    2016-08-10 4 S $26.96 $12,074,225 I/I (447,857) 1,728,000 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-12-21 4 S $27.50 $6,887,612 I/I (250,000) 7,650,000 0 -
OTIC Otonomy, Inc. Director   –       •      –    2015-11-23 4 S $28.45 $2,298,760 I/I (80,800) 1,953,300 0 -
OTIC Otonomy, Inc. Director   –       •      –    2015-11-20 4 S $28.59 $2,398,701 I/I (83,900) 2,034,100 0 -
OTIC Otonomy, Inc. Director   –       •      –    2015-11-19 4 S $28.60 $3,640,780 I/I (127,300) 2,118,000 0 -
OTIC Otonomy, Inc. Director   –       •      –    2015-11-30 4 S $28.64 $95,026 I/I (3,306) 1,850,094 0 -
OTIC Otonomy, Inc. Director   –       •      –    2015-11-24 4 S $28.75 $1,037,875 I/I (36,100) 1,917,200 0 -
  248  Records found
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  Page 9 of 10  
 
Free Registration Required For Full Results.    Limit: 25

 
 
  Transaction Code Key: Ownership Code Key
  B - Buy AB - Automatic Buy D - Direct Ownership
  S - Sell AS - Automatic Sell I - Indirect Ownership
OE - Options Exercised A - Aquired
  IO - Initital Ownership D - Disposed
 
 
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