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Insider Information:   Isaly Samuel D
Relationship:   10% Owner
City:   New York
State:   NY
   
Insider Summary:
  
   
Companies Owned :   37    
Direct Shares   1,096,936    

Indirect Shares

   81,677,812      
Direct Value   $110    

Indirect Value

   $1,070,138,900      
Total Shares   82,774,748      
Total Value   $1,070,139,010      


American Cryostem Corporation $110 American Cryostem Corporation $110
 


Historical Performance :
Based on 6 Month Return Percentages
Buys 
Sells 

     Total Filings :
    4   
    0    

     Stock price went up :
    4   
    0    
     Stock price went down :
    0   
    0    
   
     Gain/Loss Ratio :
   4.0   
   0.0   
     Percentage Gain/Loss :
   54.4%
   0.0%
     
   
Holdings :
     Menu Company Name Ticker Relation Direct Date Direct Shares Indirect Date Indirect Shares Total Value Sold  
            American Cryostem Corporation CRYO Director, 10% Owner 2005-07-13 1,096,936 2005-07-13 1,231,936    Premium*  
            Volcano Corp VOLC Director 2006-06-20 0 2006-06-20 195,705    Premium*  
            Aryx Therapeutics Inc ARYX 10% Owner 2007-11-13 0 2009-05-22 1,340,139    Premium*  
            Albireo Pharma Inc ALBO Director 2008-02-12 0 2009-06-10 1,485,904    Premium*  
            Athersys Inc (New) ATHX 10% Owner 2008-05-21 0 2011-04-26 15,250    Premium*  
            Nxstage Medical, Inc. NXTM Director 2010-12-09 0 2010-12-09 2,690,476    Premium*  
            Kun Run Biotechnology Inc KURU 10% Owner 0 2010-04-30 5,228,758    Premium*  
            Anthera Pharmaceuticals Inc ANTH Director 2010-09-30 0 2013-01-30 7,462,000    Premium*  
            Amarin Corp Plc AMRN Director 0 2012-09-04 5,700    Premium*  
            Pacira Pharmaceuticals, Inc. PCRX 10% Owner 0 2012-03-12 2,446,000    Premium*  
            Chemocentryx, Inc. CCXI 10% Owner 2012-02-13 0 2012-02-13 908,509    Premium*  
            Supernus Pharmaceuticals Inc SUPN Director, 10% Owner 2012-05-04 0 2012-05-04 297,815    Premium*  
            Mirati Therapeutics, Inc. MRTX 10% Owner 0 2015-02-03 1,267,000    Premium*  
            Acceleron Pharma Inc XLRN Former 10% Owner 2013-09-24 0 2013-09-24 576,889    Premium*  
            Relypsa Inc RLYP 10% Owner 2013-11-20 0 2016-07-25 3,356,400    Premium*  
            Roka Bioscience, Inc. ROKA 10% Owner 0 2017-10-03 0    Premium*  
            Loxo Oncology, Inc. LOXO Director 2014-08-06 0 2017-12-08 941,000    Premium*  
            Otonomy, Inc. OTIC Director 2014-08-18 0 2015-11-30 1,850,094    Premium*  
            Sientra, Inc. SIEN 10% Owner 0 2015-10-12 17,100    Premium*  
            Pieris Pharmaceuticals, Inc. PIRS 10% Owner 0 2018-01-03 49,270    Premium*  
            Glaukos Corp GKOS Director 2015-06-30 0 2017-09-05 7,895    Premium*  
            Dimension Therapeutics, Inc. DMTX Director, 10% Owner 2015-10-27 0 2015-10-27 5,397,698    Premium*  
            Adaptimmune Therapeutics PLC ADAP Director 0 2017-03-27 6,149,377    Premium*  
            Viewray, Inc. VRAY Director, 10% Owner 0 2017-01-18 89,225    Premium*  
            Aeglea Biotherapeutics, Inc. AGLE 10% Owner 0 2017-02-21 1,469,524    Premium*  
            Intellia Therapeutics, Inc. NTLA Director 2016-05-11 0 2016-05-11 2,662,180    Premium*  
            Corvus Pharmaceuticals, Inc. CRVS Director, 10% Owner 2016-05-18 0 2016-06-24 5,379,349    Premium*  
            Selecta Biosciences Inc SELB Director, 10% Owner 0 2016-06-27 1,825,415    Premium*  
            Steadymed Ltd. STDY 10% Owner 0 2017-04-25 2,123,098    Premium*  
            Nabriva Therapeutics AG NBRV Director, 10% Owner 0 2016-12-30 391,960    Premium*  
            Aadi Bioscience, Inc AADI Director, 10% Owner 2017-03-15 0 2017-03-15 4,416,446    Premium*  
            Cti Biopharma Corporation CTIC 10% Owner 2017-06-13 0 2017-06-13 5,000,000    Premium*  
            Alpine Immune Sciences Inc ALPN Director, 10% Owner 2017-07-24 0 2017-07-24 3,298,516    Premium*  
            Kala Pharmaceuticals, Inc. KALA 10% Owner 2017-07-25 0 2018-01-12 2,692,715    Premium*  
            Audentes Therapeutics, Inc. BOLD 10% Owner 2017-09-07 0 2017-09-29 4,129,638    Premium*  
            Scpharmaceuticals Inc. SCPH 10% Owner 2017-11-21 0 2017-11-21 3,409,865    Premium*  
            X4 Pharmaceuticals Inc XFOR 10% Owner 2017-11-20 0 2017-11-20 1,868,966    Premium*  
* Premium Members only  

Records found :    251         Free Registration Required For Full Results.    Limit: 25

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  Page 6 of 11
Ticker Company Name Relation   Off-Dir-10% Trans. Date Form Action Price Mkt Value D/I Shares    Holdings   
Rank

  
3m +/-  
Form
OTIC Otonomy, Inc. 10% Owner   –       –       •   2014-08-18 4 B $16.00 $2,750,000 I/I 171,875 2,256,398 1.5 -
RLYP Relypsa Inc 10% Owner   –       –       •   2014-09-16 4 S $25.45 $1,146,836 I/I (45,000) 8,906,551 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2014-09-17 4 S $25.07 $1,228,430 I/I (49,000) 8,857,551 0 -
MRTX Mirati Therapeutics, Inc. 10% Owner   –       –       •   2015-02-03 4 B $20.00 $2,000,000 I/I 100,000 1,267,000 1.5 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-05-18 4 S $34.13 $49,746,216 I/I (1,457,551) 7,400,000 0 -
GKOS Glaukos Corp Director   –       •       •   2015-06-30 4 OE $0.00 $0 I/I 27,607 27,455 0 -
GKOS Glaukos Corp Director   –       •       •   2015-06-30 4 D $18.00 $211,212 I/I (11,734) 27,344 0 -
GKOS Glaukos Corp Director   –       •       •   2015-06-30 4 A $0.00 $0 I/I 2,882,064 27,194 0 -
PIRS Pieris Pharmaceuticals, I... Director   –       •       •   2015-07-06 4 B $2.75 $1,375,000 I/I 500,000 65,398 2.25 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-09-24 4 S $9.78 $91,359 I/I (8,306) 3,147,102 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-09-25 4 S $10.07 $1,396,040 I/I (132,000) 28,789 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-09-28 4 S $10.30 $109,201 I/I (10,602) 28,700 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-09-29 4 S $10.08 $106,425 I/I (10,558) 28,611 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-09-30 4 S $10.17 $445,853 I/I (43,840) 28,242 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-01 4 S $10.34 $491,150 I/I (47,500) 27,842 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-02 4 S $10.34 $495,286 I/I (47,900) 27,439 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-05 4 S $8.19 $1,131,039 I/I (138,100) 26,276 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-06 4 S $7.80 $54,600 I/I (7,000) 26,217 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-07 4 S $7.36 $396,704 I/I (53,900) 25,763 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-08 4 S $7.24 $2,896,000 I/I (400,000) 21,926 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-09 4 S $7.03 $1,495,344 I/I (212,709) 19,885 0 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-12 4 S $5.98 $1,721,588 I/I (287,891) 17,100 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-10-22 4 B $11.97 $6,280,165 I/I 500,000 7,900,000 1.5 -
DMTX Dimension Therapeutics, I... Director   –       •       •   2015-10-27 4 A $0.00 $0 I/I 5,197,698 5,197,698 0 -
DMTX Dimension Therapeutics, I... Director   –       •       •   2015-10-27 4 B $13.00 $2,600,000 I/I 200,000 5,397,698 2.25 -
  251  Records found
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  Page 6 of 11  
 
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  Transaction Code Key: Ownership Code Key
  B - Buy AB - Automatic Buy D - Direct Ownership
  S - Sell AS - Automatic Sell I - Indirect Ownership
OE - Options Exercised A - Aquired
  IO - Initital Ownership D - Disposed
 
 
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