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Insider Information:   Isaly Samuel D
Relationship:   10% Owner
City:   New York
State:   NY
   
Insider Summary:
  
   
Companies Owned :   37    
Direct Shares   1,096,936    

Indirect Shares

   81,677,812      
Direct Value   $110    

Indirect Value

   $1,070,138,900      
Total Shares   82,774,748      
Total Value   $1,070,139,010      


American Cryostem Corporation $110 American Cryostem Corporation $110
 


Historical Performance :
Based on 6 Month Return Percentages
Buys 
Sells 

     Total Filings :
    4   
    0    

     Stock price went up :
    4   
    0    
     Stock price went down :
    0   
    0    
   
     Gain/Loss Ratio :
   4.0   
   0.0   
     Percentage Gain/Loss :
   54.4%
   0.0%
     
   
Holdings :
     Menu Company Name Ticker Relation Direct Date Direct Shares Indirect Date Indirect Shares Total Value Sold  
            American Cryostem Corporation CRYO Director, 10% Owner 2005-07-13 1,096,936 2005-07-13 1,231,936    Premium*  
            Volcano Corp VOLC Director 2006-06-20 0 2006-06-20 195,705    Premium*  
            Aryx Therapeutics Inc ARYX 10% Owner 2007-11-13 0 2009-05-22 1,340,139    Premium*  
            Albireo Pharma Inc ALBO Director 2008-02-12 0 2009-06-10 1,485,904    Premium*  
            Athersys Inc (New) ATHX 10% Owner 2008-05-21 0 2011-04-26 15,250    Premium*  
            Nxstage Medical, Inc. NXTM Director 2010-12-09 0 2010-12-09 2,690,476    Premium*  
            Kun Run Biotechnology Inc KURU 10% Owner 0 2010-04-30 5,228,758    Premium*  
            Anthera Pharmaceuticals Inc ANTH Director 2010-09-30 0 2013-01-30 7,462,000    Premium*  
            Amarin Corp Plc AMRN Director 0 2012-09-04 5,700    Premium*  
            Pacira Pharmaceuticals, Inc. PCRX 10% Owner 0 2012-03-12 2,446,000    Premium*  
            Chemocentryx, Inc. CCXI 10% Owner 2012-02-13 0 2012-02-13 908,509    Premium*  
            Supernus Pharmaceuticals Inc SUPN Director, 10% Owner 2012-05-04 0 2012-05-04 297,815    Premium*  
            Mirati Therapeutics, Inc. MRTX 10% Owner 0 2015-02-03 1,267,000    Premium*  
            Acceleron Pharma Inc XLRN Former 10% Owner 2013-09-24 0 2013-09-24 576,889    Premium*  
            Relypsa Inc RLYP 10% Owner 2013-11-20 0 2016-07-25 3,356,400    Premium*  
            Roka Bioscience, Inc. ROKA 10% Owner 0 2017-10-03 0    Premium*  
            Loxo Oncology, Inc. LOXO Director 2014-08-06 0 2017-12-08 941,000    Premium*  
            Otonomy, Inc. OTIC Director 2014-08-18 0 2015-11-30 1,850,094    Premium*  
            Sientra, Inc. SIEN 10% Owner 0 2015-10-12 17,100    Premium*  
            Pieris Pharmaceuticals, Inc. PIRS 10% Owner 0 2018-01-03 49,270    Premium*  
            Glaukos Corp GKOS Director 2015-06-30 0 2017-09-05 7,895    Premium*  
            Dimension Therapeutics, Inc. DMTX Director, 10% Owner 2015-10-27 0 2015-10-27 5,397,698    Premium*  
            Adaptimmune Therapeutics PLC ADAP Director 0 2017-03-27 6,149,377    Premium*  
            Viewray, Inc. VRAY Director, 10% Owner 0 2017-01-18 89,225    Premium*  
            Aeglea Biotherapeutics, Inc. AGLE 10% Owner 0 2017-02-21 1,469,524    Premium*  
            Intellia Therapeutics, Inc. NTLA Director 2016-05-11 0 2016-05-11 2,662,180    Premium*  
            Corvus Pharmaceuticals, Inc. CRVS Director, 10% Owner 2016-05-18 0 2016-06-24 5,379,349    Premium*  
            Selecta Biosciences Inc SELB Director, 10% Owner 0 2016-06-27 1,825,415    Premium*  
            Steadymed Ltd. STDY 10% Owner 0 2017-04-25 2,123,098    Premium*  
            Nabriva Therapeutics AG NBRV Director, 10% Owner 0 2016-12-30 391,960    Premium*  
            Aadi Bioscience, Inc AADI Director, 10% Owner 2017-03-15 0 2017-03-15 4,416,446    Premium*  
            Cti Biopharma Corporation CTIC 10% Owner 2017-06-13 0 2017-06-13 5,000,000    Premium*  
            Alpine Immune Sciences Inc ALPN Director, 10% Owner 2017-07-24 0 2017-07-24 3,298,516    Premium*  
            Kala Pharmaceuticals, Inc. KALA 10% Owner 2017-07-25 0 2018-01-12 2,692,715    Premium*  
            Audentes Therapeutics, Inc. BOLD 10% Owner 2017-09-07 0 2017-09-29 4,129,638    Premium*  
            Scpharmaceuticals Inc. SCPH 10% Owner 2017-11-21 0 2017-11-21 3,409,865    Premium*  
            X4 Pharmaceuticals Inc XFOR 10% Owner 2017-11-20 0 2017-11-20 1,868,966    Premium*  
* Premium Members only  

Records found :    251         Free Registration Required For Full Results.    Limit: 25

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  Page 8 of 11
Ticker Company Name Relation   Off-Dir-10% Trans. Date Form Action Price Mkt Value D/I Shares    Holdings   
Rank

  
3m +/-  
Form
GKOS Glaukos Corp Director   –       •      –    2017-08-17 4 S $37.85 $8,588,922 I/I (226,920) 13,369 0 -
AMRN Amarin Corp Plc Director   –       •      –    2012-09-04 4 AS $14.43 $3,372,992 I/I (233,700) 5,700 0 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-12-21 4 S $27.50 $6,887,612 I/I (250,000) 7,650,000 0 -
NTLA Intellia Therapeutics, In... Director   –       •      –    2016-05-11 4 B $18.00 $4,500,000 I/I 250,000 2,662,180 2.1 -
LOXO Loxo Oncology, Inc. Director   –       •      –    2017-12-08 4 S $82.50 $20,625,000 I/I (250,000) 941,000 0 -
LOXO Loxo Oncology, Inc. Director   –       •      –    2017-11-22 4 S $75.00 $20,025,000 I/I (267,000) 1,191,000 0 -
ATHX Athersys Inc (New) Director   –       •       •   2008-05-22 4 B $2.40 $643,200 I/I 268,000 3,448,000 2.25 -
LOXO Loxo Oncology, Inc. Director   –       •      –    2017-11-16 4 S $72.46 $20,051,389 I/I (270,000) 1,458,000 0 -
LOXO Loxo Oncology, Inc. 10% Owner   –       –       •   2014-08-06 4 B $13.00 $3,580,005 I/I 275,385 2,175,857 1.5 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-12 4 S $5.98 $1,721,588 I/I (287,891) 17,100 0 -
NXTM Nxstage Medical, Inc. Director   –       •       •   2010-08-17 4 S $17.06 $4,913,280 I/I (288,000) 4,300,000 0 -
ARYX Aryx Therapeutics Inc Director   –       •      –    2007-11-13 4 B $10.00 $3,000,000 I/I 300,000 2,125,493 2.1 -
ALBO Albireo Pharma Inc Director   –       •      –    2009-06-09 4 D $0.00 $0 I/I (300,000) 1,512,892 0 -
KALA Kala Pharmaceuticals, Inc... See Remarks   –       –       •   2017-07-25 4 B $15.00 $4,789,995 I/I 319,333 2,375,279 1.5 -
VRAY Viewray, Inc. Director   –       •       •   2017-01-18 4 B $3.00 $991,731 I/I 330,577 89,225 2.25 -
RLYP Relypsa Inc 10% Owner   –       –       •   2016-07-25 4 S $31.98 $10,988,328 I/I (343,600) 3,356,400 0 -
AMRN Amarin Corp Plc Director   –       •      –    2012-07-27 4 AS $14.61 $5,350,691 I/I (366,300) 7,944 0 -
ROKA Roka Bioscience, Inc. 10% Owner   –       –       •   2017-09-28 4 S $0.72 $273,990 I/I (380,542) 2,787 0 -
ROKA Roka Bioscience, Inc. 10% Owner   –       –       •   2014-07-22 4 B $12.00 $4,599,996 I/I 383,333 30,378 1.5 -
SIEN Sientra, Inc. 10% Owner   –       –       •   2015-10-08 4 S $7.24 $2,896,000 I/I (400,000) 21,926 0 -
GKOS Glaukos Corp Director   –       •      –    2016-08-03 4 S $30.59 $13,000,750 I/I (425,000) 23,334 0 -
GKOS Glaukos Corp Director   –       •      –    2017-09-05 4 S $37.94 $16,621,730 I/I (425,200) 7,895 0 -
LOXO Loxo Oncology, Inc. Director   –       •      –    2016-08-10 4 S $26.96 $12,074,225 I/I (447,857) 1,728,000 0 -
PIRS Pieris Pharmaceuticals, I... Director   –       •       •   2015-07-06 4 B $2.75 $1,375,000 I/I 500,000 65,398 2.25 -
RLYP Relypsa Inc 10% Owner   –       –       •   2015-10-22 4 B $11.97 $6,280,165 I/I 500,000 7,900,000 1.5 -
  251  Records found
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  Transaction Code Key: Ownership Code Key
  B - Buy AB - Automatic Buy D - Direct Ownership
  S - Sell AS - Automatic Sell I - Indirect Ownership
OE - Options Exercised A - Aquired
  IO - Initital Ownership D - Disposed
 
 
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