Opaleye Management Inc. : Portfolio Holdings

Portfolio Summary	View Filing
Filing Report Date :	2024-03-31
Total Value :	$433,723,000
Total Value Change :	$60,571,000
Securities Held Change :	5

All Securities Held :	50
New Positions :	12
Closed Positions :	7
Increased Positions :	16
Unchanged Positions :	6
Decreased Positions :	16

Download

		Free Registration Required For Full Results
Holdings Found : 57		View All Holdings	Currently Viewing: ALL				Page 1 of 1

Menu	Ticker	Company Name	Position Rank	New/Closed Postion	Last Close	Value	Shares Held	% of Portfolio	Value Change	Change In Shares Held	% of Company	Industry
	OCUL	Ocular Therapeutix, Inc	1	-	$0.00	$60,544,000	6,653,138	13.96%	33,472,000	583,138	6.036	N/A
	HROW	Harrow Health Inc	2	-	$17.22	$51,870,000	3,920,600	11.96%	9,086,000	100,600	15.226	Biotechnology
	TGTX	TG Therapeutics Inc	3	-	$17.70	$34,679,000	2,280,000	8%	-3,153,000	65,000	1.769	Drug Manufacturers - ...
	KROS	Keros Therapeutics, Inc.	4	-	$0.00	$24,329,000	367,500	5.61%	10,115,000	10,000	1.082	N/A
	RYTM	Rhythm Pharmaceuticals, Inc.	5	-	$37.84	$22,315,000	515,000	5.14%	-5,727,000	-95,000	0.726	N/A
	CPRX	Catalyst Pharmaceutical Par...	6	-	$16.14	$16,009,000	1,004,355	3.69%	-5,427,000	-252,845	0.969	Drugs - Generic
	ARVN	Arvinas Holding Company, Llc	7	-	$35.95	$13,622,000	330,000	3.14%	2,768,000	66,300	0.48	N/A
	IOVA	Iovance Biotherapeutics Inc	8	-	$10.33	$13,294,000	897,000	3.07%	6,001,000	0	0.419	N/A
	JSPR	Jasper Therapeutics Ord Shs	9	-	$15.12	$12,788,000	435,573	2.95%	9,644,000	-3,549,767	0.429	N/A
	EWTX	Edgewise Therapeutics, Inc.	10	-	$0.00	$12,130,000	665,000	2.8%	4,483,000	-34,000	0.721	N/A
	FDMT	4d Molecular Therapeutics Inc.	11	-	$0.00	$10,964,000	344,123	2.53%	4,714,000	35,623	0.697	N/A
	CDXS	Codexis Inc	12	-	$3.47	$10,889,000	3,120,000	2.51%	1,600,000	74,475	4.809	Biotechnology
	TARA	Protara Therapeutics, Inc	13	-	$2.99	$10,797,000	2,692,594	2.49%	5,748,000	0	25.619	N/A
	SLRN	Acelyrin, Inc.	14	-	$4.52	$10,665,000	1,580,000	2.46%	-20,265,000	-2,566,138	1.626	N/A
	ETON	Eton Pharmaceuticals, Inc.	15	-	$0.00	$9,172,000	2,445,781	2.11%	-1,909,000	-84,106	13.889	N/A
	TRVI	Trevi Therapeutics, Inc.	16	-	$0.00	$9,125,000	2,645,000	2.1%	5,728,000	110,000	4.414	N/A
	LYEL	Lyell Immunopharma, Inc.	17	New	$2.76	$7,482,000	3,355,000	1.73%	7,482,000	3,355,000	1.382	N/A
	NAMS	Newamsterdam Pharma Ord Shs	18	-	$0.00	$7,459,000	315,388	1.72%	4,495,000	50,000	0.387	N/A
	VTYX	Ventyx Biosciences, Inc.	19	-	$4.68	$7,068,000	1,285,000	1.63%	4,252,000	145,000	2.555	N/A
	NTLA	Intellia Therapeutics, Inc.	20	-	$25.97	$7,015,000	255,000	1.62%	3,996,000	156,000	0.285	N/A
	CMPX	Compass Therapeutics Ord Shs	21	New	$0.00	$6,277,000	3,170,000	1.45%	6,277,000	3,170,000	3.234	N/A
	XOMA	XOMA Corporation	22	-	$25.20	$6,013,000	250,000	1.39%	1,388,000	0	2.218	Biotechnology
	LQDA	Liquidia Technologies Inc	23	-	$13.13	$5,826,000	395,000	1.34%	473,000	-50,000	1.046	N/A
	PCVX	Vaxcyte, Inc.	24	-	$0.00	$5,806,000	85,000	1.34%	154,000	-5,000	0.079	N/A
	NYXH	Nyxoah Ord Shs	25	-	$0.00	$4,317,000	320,000	1%	2,717,000	-24,800	1.252	N/A
	SVRA	Savara Inc	26	New	$4.33	$4,258,000	855,000	0.98%	4,258,000	855,000	0.632	Biotechnology
	SYRS	Syros Pharmaceuticals, Inc.	27	-	$5.36	$4,213,000	787,545	0.97%	1,414,000	428,175	1.401	N/A
	URGN	Urogen Pharma Ltd.	28	-	$13.31	$4,050,000	270,000	0.93%	-750,000	-50,000	1.222	N/A
	RVNC	Revance Therapeutics, Inc.	29	New	$2.92	$3,862,000	785,000	0.89%	3,862,000	785,000	0.954	N/A
	APLT	Applied Therapeutics Inc.	30	-	$0.00	$3,660,000	1,770,000	0.84%	0	677,500	2.292	N/A
	RLMD	Relmada Therapeutics, Inc.	31	-	$3.09	$3,529,000	759,000	0.81%	-102,000	-118,000	2.737	N/A
	PTGX	Protagonist Therapeutics, Inc	32	-	$31.71	$3,260,000	112,700	0.75%	676,000	0	0.195	N/A
	ZNTL	Zentalis Pharmaceuticals, Llc	33	New	$0.00	$3,152,000	200,000	0.73%	3,152,000	200,000	0.236	N/A
	ALLK	Allakos Inc.	34	New	$1.36	$3,068,000	2,435,000	0.71%	3,068,000	2,435,000	2.858	N/A
	GOSS	Gossamer Bio Inc	35	-	$0.64	$2,879,000	2,440,109	0.66%	158,000	-542,091	1.083	N/A
	IBIO	Ibio Ord Shs	36	New	$0.20	$2,761,000	680,000	0.64%	2,761,000	680,000	0.756	Drug Manufacturers - ...
	VSTM	Verastem, Inc.	37	-	$11.88	$2,495,000	211,400	0.58%	774,000	0	0.838	Biotechnology
	ALGS	Aligos Therapeutics, Inc.	38	-	$0.00	$1,597,000	1,630,000	0.37%	736,000	333,000	2.264	N/A
	CNTX	Context Therapeutics Inc.	39	-	$0.00	$1,530,000	1,108,357	0.35%	428,000	133,357	6.944	N/A
	PGEN	Precigen Inc	40	-	$1.38	$1,374,000	947,500	0.32%	17,000	-65,000	0.531	Biotechnology
	LRMR	Larimar Therapeutics Inc	41	-	$1.15	$1,324,000	174,413	0.31%	-1,513,000	-449,087	0.437	N/A
	FULC	Fulcrum Therapeutics, Inc.	42	-	$0.00	$1,227,000	130,000	0.28%	349,000	0	0.206	N/A
	MOR	Morphosys Ag	43	-	$18.30	$1,179,000	65,000	0.27%	-257,000	-80,000	0.05	N/A
	GKOS	Glaukos Corp	44	New	$107.73	$809,000	8,576	0.19%	809,000	8,576	0.016	N/A
	PMVP	Pmv Pharmaceuticals, Inc.	45	New	$0.00	$802,000	471,481	0.18%	802,000	471,481	0.867	N/A
	BDSX	Biodesix Inc	46	-	$0.00	$765,000	534,657	0.18%	-2,846,000	38,157	2.015	N/A
	RGLS	Regulus Therapeutics Inc.	47	New	$1.92	$490,000	170,308	0.11%	490,000	170,308	0.117	Biotechnology
	DSGN	Design Therapeutics, Inc.	48	New	$0.00	$456,000	113,038	0.11%	456,000	113,038	0.203	N/A
	RPTX	Repare Therapeutics Inc.	49	New	$0.00	$318,000	67,561	0.07%	318,000	67,561	0.184	N/A
	CRNX	Crinetics Pharmaceuticals, ...	50	-	$50.54	$210,000	210,000	0.05%	-10,731,000	-97,500	0.286	N/A
	BHVN	Biohaven Ltd.	56	Closed	$37.99	$0	0	0%	-8,560,000	-200,000	0	N/A
	IDYA	Ideaya Biosciences, Inc.	55	Closed	$0.00	$0	0	0%	-11,083,000	-311,500	0	N/A
	KALV	Kalvista Pharmaceuticals Inc	54	Closed	$11.69	$0	0	0%	-1,838,000	-150,000	0	N/A
	KNSA	Kiniksa Pharmaceuticals, Ltd.	53	Closed	$19.27	$0	0	0%	-640,000	-37,500	0	N/A
	STRO	Sutro Biopharma Inc	52	Closed	$4.26	$0	0	0%	-1,293,000	-301,491	0	N/A
	MRNS	Marinus Pharmaceuticals Inc	51	Closed	$1.29	$0	0	0%	-6,125,000	-563,500	0	N/A
	ARQT	Arcutis Biotherapeutics, Inc.	57	Closed	$9.92	$0	0	0%	-6,331,000	-1,960,000	0	N/A

57 Records Found

Page 1 of 1

Download:

Download: Holdings - Current Quarter Only

Summary:

Free Registration Required For Full Results