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10021 |
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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
BGNE |
Beigene Ltd |
1 |
- |
$264.42 |
$2,394,838,000 |
8,799,053 |
26.8% |
634,204,000 |
-732,827 |
9.709 |
N/A |
|
|
INCY |
Incyte Corp |
2 |
- |
$71.22 |
$1,861,304,000 |
30,739,953 |
20.83% |
-261,871,000 |
487 |
14.037 |
Biotechnology |
|
|
ACAD |
Acadia Pharmaceuticals Inc |
3 |
- |
$22.14 |
$712,202,000 |
42,877,916 |
7.97% |
-74,608,000 |
0 |
26.672 |
Biotechnology |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
4 |
- |
$285.06 |
$654,043,000 |
1,974,590 |
7.32% |
44,744,000 |
0 |
7.68 |
Diagnostic Substances |
|
|
SMMT |
Summit Therapeutics Inc |
5 |
- |
$19.95 |
$471,156,000 |
24,424,865 |
5.27% |
35,294,000 |
0 |
3.485 |
N/A |
|
|
INSM |
Insmed Inc |
6 |
- |
$101.59 |
$410,488,000 |
5,380,626 |
4.59% |
64,814,000 |
373,763 |
2.832 |
Biotechnology |
|
|
RYTM |
Rhythm Pharmaceuticals, Inc. |
7 |
- |
$62.39 |
$296,869,000 |
5,604,483 |
3.32% |
-43,727,000 |
-479,766 |
7.901 |
N/A |
|
|
RVMD |
Revolution Medicines, Inc. |
8 |
- |
$39.77 |
$280,651,000 |
7,936,972 |
3.14% |
-66,512,000 |
0 |
4.669 |
N/A |
|
|
KYMR |
Kymera Therapeutics, Inc. |
9 |
- |
$0.00 |
$164,109,000 |
5,995,929 |
1.84% |
-77,107,000 |
0 |
8.484 |
N/A |
|
|
ALKS |
Alkermes Plc |
10 |
- |
$29.42 |
$148,038,000 |
4,483,285 |
1.66% |
27,771,000 |
301,534 |
2.441 |
Drug Delivery |
|
|
EWTX |
Edgewise Therapeutics, Inc. |
11 |
- |
$14.68 |
$135,431,000 |
6,155,940 |
1.52% |
-28,933,000 |
0 |
5.968 |
N/A |
|
|
REPL |
Replimune Group Inc |
12 |
- |
$9.83 |
$107,692,000 |
11,045,336 |
1.21% |
-26,067,000 |
0 |
15.273 |
N/A |
|
|
IMVT |
Immunovant Inc |
13 |
- |
$0.00 |
$93,275,000 |
5,457,881 |
1.04% |
50,971,000 |
3,750,000 |
6.268 |
N/A |
|
|
BCYC |
Bicycle Therapeutics Ltd |
14 |
- |
$0.00 |
$92,417,000 |
10,885,357 |
1.03% |
-59,978,000 |
0 |
15.778 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
15 |
- |
$32.91 |
$68,913,000 |
2,322,656 |
0.77% |
24,211,000 |
807,338 |
4.645 |
N/A |
|
|
KNSA |
Kiniksa Pharmaceuticals, Ltd. |
16 |
- |
$28.41 |
$62,595,000 |
2,818,323 |
0.7% |
6,849,000 |
0 |
6.967 |
N/A |
|
|
ABCL |
Abcellera Biologics Inc. |
17 |
- |
$0.00 |
$61,382,000 |
27,525,640 |
0.69% |
-19,268,000 |
0 |
10.225 |
N/A |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
18 |
- |
$37.11 |
$57,071,000 |
1,576,114 |
0.64% |
-9,236,000 |
0 |
1.711 |
Restaurants |
|
|
DNLI |
Denali Therapeutics Inc. |
19 |
- |
$14.62 |
$50,732,000 |
3,731,695 |
0.57% |
-25,320,000 |
0 |
2.61 |
N/A |
|
|
KOD |
Kodiak Sciences Inc. |
20 |
- |
$3.74 |
$48,556,000 |
17,310,490 |
0.54% |
-123,683,000 |
0 |
38.64 |
N/A |
|
|
NRIX |
Nurix Therapeutics, Inc. |
21 |
- |
$0.00 |
$46,120,000 |
3,882,125 |
0.52% |
-27,019,000 |
0 |
5.468 |
N/A |
|
|
ARGX |
Argenx Se |
22 |
- |
$551.22 |
$46,023,000 |
77,760 |
0.52% |
-22,798,000 |
-34,144 |
0.165 |
N/A |
|
|
TRDA |
Entrada Therapeutics, Inc. |
23 |
- |
$0.00 |
$43,987,000 |
4,865,819 |
0.49% |
-40,143,000 |
0 |
15.59 |
N/A |
|
|
CELC |
Celcuity Inc. |
24 |
- |
$12.46 |
$43,046,000 |
4,257,735 |
0.48% |
7,984,000 |
1,579,182 |
11.498 |
N/A |
|
|
GRAL |
Grail, Llc |
25 |
- |
$42.52 |
$41,633,000 |
1,630,125 |
0.47% |
12,535,000 |
0 |
5.242 |
N/A |
|
|
ROIV |
Roivant Sciences Ltd. |
26 |
- |
$11.08 |
$38,017,000 |
3,767,773 |
0.43% |
-6,556,000 |
0 |
0.544 |
N/A |
|
|
IMTX |
Immatics N.V |
27 |
- |
$6.10 |
$32,814,000 |
7,275,830 |
0.37% |
-18,917,000 |
0 |
7.056 |
N/A |
|
|
STOK |
Stoke Therapeutics, Inc. |
28 |
- |
$11.70 |
$30,815,000 |
4,633,838 |
0.34% |
-20,296,000 |
0 |
7.396 |
N/A |
|
|
CERS |
Cerus Corp |
29 |
- |
$1.41 |
$26,898,000 |
19,351,087 |
0.3% |
-3,097,000 |
-126,252 |
11.578 |
Biotechnology |
|
|
PCVX |
Vaxcyte, Inc. |
30 |
- |
$0.00 |
$24,200,000 |
640,885 |
0.27% |
20,198,000 |
592,000 |
0.47 |
N/A |
|
|
GLUE |
Monte Rosa Therapeutics, Inc. |
31 |
- |
$0.00 |
$22,811,000 |
4,916,095 |
0.26% |
-11,307,000 |
0 |
8.011 |
N/A |
|
|
CRSP |
Crispr Therapeutics Ag |
32 |
- |
$41.58 |
$22,259,000 |
654,099 |
0.25% |
-29,224,000 |
-653,912 |
0.926 |
N/A |
|
|
AKRO |
Akero Therapeutics, Inc. |
33 |
- |
$0.00 |
$22,212,000 |
548,713 |
0.25% |
-8,309,000 |
-548,369 |
0.727 |
N/A |
|
|
SERA |
Sera Prognostics, Inc. |
34 |
- |
$1.78 |
$20,233,000 |
5,498,170 |
0.23% |
-24,003,000 |
63,771 |
18.772 |
N/A |
|
|
CNTA |
Centessa Pharmaceuticals Plc |
35 |
- |
$0.00 |
$17,647,000 |
1,227,178 |
0.2% |
-2,908,000 |
0 |
0.937 |
N/A |
|
|
NGNE |
Neurogene |
36 |
- |
$3.68 |
$17,403,000 |
1,486,200 |
0.19% |
1,985,000 |
811,750 |
3.548 |
N/A |
|
|
IDYA |
Ideaya Biosciences, Inc. |
37 |
- |
$0.00 |
$17,398,000 |
1,062,123 |
0.19% |
-9,899,000 |
0 |
1.089 |
N/A |
|
|
VRNA |
Verona Pharma Plc |
38 |
New |
$0.00 |
$14,212,000 |
223,843 |
0.16% |
14,212,000 |
223,843 |
0.277 |
N/A |
|
|
CADL |
Candel Therapeutics, Inc. |
39 |
- |
$0.00 |
$13,770,000 |
2,437,189 |
0.15% |
-12,114,000 |
-544,794 |
8.495 |
N/A |
|
|
PRAX |
Praxis Precision Medicines,... |
40 |
- |
$0.00 |
$12,555,000 |
331,533 |
0.14% |
-12,960,000 |
0 |
0.633 |
N/A |
|
|
TSVT |
2seventy Bio, Inc. |
41 |
- |
$0.00 |
$12,338,000 |
2,497,526 |
0.14% |
4,995,000 |
0 |
4.807 |
N/A |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
42 |
- |
$0.00 |
$11,656,000 |
347,408 |
0.13% |
-27,296,000 |
-646,271 |
0.461 |
N/A |
|
|
BCAX |
Bicara Therapeutics Inc. |
43 |
- |
$10.00 |
$10,858,000 |
833,333 |
0.12% |
-3,659,000 |
0 |
1.532 |
N/A |
|
|
IONS |
Ionis Pharmaceuticals Inc |
44 |
- |
$35.24 |
$10,798,000 |
357,915 |
0.12% |
-1,715,000 |
0 |
0.227 |
Drug Manufacturers - ... |
|
|
DBVT |
DBV Technologies SA |
45 |
- |
$0.61 |
$9,967,000 |
1,461,425 |
0.11% |
5,451,000 |
0 |
5.813 |
N/A |
|
|
ALMS |
Alumis Inc. |
46 |
- |
$3.13 |
$9,594,000 |
1,562,500 |
0.11% |
-2,687,000 |
0 |
3.309 |
N/A |
|
|
MRUS |
Merus Nv |
47 |
- |
$53.30 |
$9,407,000 |
223,500 |
0.11% |
-9,516,000 |
-226,500 |
0.312 |
N/A |
|
|
PRLD |
Prelude Therapeutics Inc |
48 |
- |
$0.00 |
$7,775,000 |
10,123,824 |
0.09% |
-5,133,000 |
0 |
23.167 |
N/A |
|
|
VERV |
Verve Therapeutics, Inc. |
49 |
- |
$0.00 |
$7,730,000 |
1,691,530 |
0.09% |
-1,810,000 |
0 |
2.103 |
N/A |
|
|
RCKT |
Rocket Pharmaceuticals |
50 |
- |
$2.88 |
$7,318,000 |
1,097,079 |
0.08% |
6,098,000 |
1,000,000 |
1.185 |
N/A |
|
|
XNCR |
Xencor Inc |
51 |
- |
$9.05 |
$7,133,000 |
670,431 |
0.08% |
-8,274,000 |
0 |
0.745 |
Biotechnology |
|
|
DYN |
Dyne Therapeutics, Inc. |
52 |
- |
$13.82 |
$7,030,000 |
672,096 |
0.08% |
-8,805,000 |
0 |
0.582 |
N/A |
|
|
KALA |
Kala Pharmaceuticals, Inc. |
53 |
- |
$4.34 |
$6,887,000 |
1,201,894 |
0.08% |
-1,454,000 |
0 |
26.072 |
N/A |
|
|
DSGN |
Design Therapeutics, Inc. |
54 |
- |
$0.00 |
$6,731,000 |
1,743,725 |
0.08% |
-4,028,000 |
0 |
3.135 |
N/A |
|
|
GPCR |
Structure Therapeutics Inc. |
55 |
- |
$20.57 |
$6,259,000 |
361,565 |
0.07% |
-3,547,000 |
0 |
0.574 |
N/A |
|
|
TSHA |
Taysha Gene Therapies, Inc. |
56 |
- |
$0.00 |
$5,567,000 |
4,004,756 |
0.06% |
-1,361,000 |
0 |
2.142 |
N/A |
|
|
RGLS |
Regulus Therapeutics Inc. |
57 |
New |
$8.22 |
$4,715,000 |
2,694,044 |
0.05% |
4,715,000 |
2,694,044 |
1.845 |
Biotechnology |
|
|
IGMS |
Igm Biosciences, Inc. |
58 |
- |
$0.00 |
$4,710,000 |
4,095,257 |
0.05% |
-20,306,000 |
953 |
16.909 |
N/A |
|
|
NTLA |
Intellia Therapeutics, Inc. |
59 |
- |
$8.96 |
$4,580,000 |
644,116 |
0.05% |
-2,930,000 |
0 |
0.634 |
N/A |
|
|
CLDX |
Celldex Therapeutics Inc |
60 |
- |
$20.34 |
$4,495,000 |
247,644 |
0.05% |
-1,763,000 |
0 |
0.336 |
Diagnostic Substances |
|
|
SION |
Sionna Therapeutics, Inc. |
61 |
New |
$0.00 |
$4,184,000 |
400,000 |
0.05% |
4,184,000 |
400,000 |
0.907 |
N/A |
|
|
BNTX |
Biontech Se Adr |
62 |
- |
$0.00 |
$4,101,000 |
45,031 |
0.05% |
-1,030,000 |
0 |
0.019 |
N/A |
|
|
TCRX |
Tscan Therapeutics, Inc. |
63 |
- |
$0.00 |
$3,843,000 |
2,784,792 |
0.04% |
-4,623,000 |
0 |
6.394 |
N/A |
|
|
IRON |
Disc Medicine, Inc |
64 |
- |
$52.02 |
$3,825,000 |
77,050 |
0.04% |
-1,060,000 |
0 |
0.259 |
N/A |
|
|
VIR |
Vir Biotechnology, Inc. |
65 |
- |
$0.00 |
$3,516,000 |
542,539 |
0.04% |
-4,445,000 |
-542,000 |
0.426 |
N/A |
|
|
SANA |
Sana Biotechnology, Inc. |
66 |
- |
$0.00 |
$3,412,000 |
2,030,949 |
0.04% |
-469,000 |
-350,000 |
1.083 |
N/A |
|
|
SGMT |
Sagimet Biosciences Inc. |
67 |
- |
$7.40 |
$3,107,000 |
952,996 |
0.03% |
-1,181,000 |
0 |
4.462 |
N/A |
|
|
RLAY |
Relay Therapeutics, Inc. |
68 |
- |
$3.27 |
$3,040,000 |
1,160,117 |
0.03% |
-1,740,000 |
0 |
0.695 |
N/A |
|
|
WVE |
Wave Life Sciences Ltd. |
69 |
- |
$6.85 |
$2,780,000 |
344,063 |
0.03% |
-1,476,000 |
0 |
0.289 |
N/A |
|
|
FATE |
Fate Therapeutics Inc |
70 |
- |
$1.24 |
$2,574,000 |
3,258,402 |
0.03% |
-2,802,000 |
0 |
1.964 |
Biotechnology |
|
|
SKYE |
Skye Bioscience Inc |
71 |
- |
$2.12 |
$2,307,000 |
1,450,638 |
0.03% |
-1,798,000 |
0 |
5.168 |
N/A |
|
|
TARA |
Protara Therapeutics, Inc |
72 |
- |
$3.17 |
$2,287,000 |
536,832 |
0.03% |
-547,000 |
0 |
5.108 |
N/A |
|
|
ELVN |
Enliven Therapeutics Ord Shs |
73 |
- |
$0.00 |
$2,260,000 |
114,833 |
0.03% |
-324,000 |
0 |
0.229 |
N/A |
|
|
CTNM |
Contineum Therapeutics, Inc. |
74 |
- |
$4.29 |
$2,181,000 |
312,500 |
0.02% |
-2,397,000 |
0 |
1.215 |
N/A |
|
|
PRME |
Prime Medicine, Inc. |
75 |
- |
$1.50 |
$2,047,000 |
1,028,466 |
0.02% |
-956,000 |
0 |
1.058 |
N/A |
|
|
TECX |
Tectonic Therapeutic Inc |
76 |
New |
$21.55 |
$1,771,000 |
100,000 |
0.02% |
1,771,000 |
100,000 |
0.679 |
N/A |
|
|
VTVT |
Vtv Therapeutics Inc. |
77 |
- |
$0.35 |
$1,685,000 |
97,314 |
0.02% |
341,000 |
0 |
0.218 |
N/A |
|
|
CMPX |
Compass Therapeutics Ord Shs |
78 |
- |
$0.00 |
$1,040,000 |
547,498 |
0.01% |
-1,219,000 |
-1,010,132 |
0.396 |
N/A |
|
|
NMRA |
Neumora Therapeutics, Inc. |
79 |
- |
$0.86 |
$1,035,000 |
1,034,600 |
0.01% |
-9,932,000 |
0 |
0.678 |
N/A |
|
|
HOOK |
Hookipa Pharma Inc. |
80 |
- |
$1.48 |
$878,000 |
812,814 |
0.01% |
-756,000 |
0 |
1.598 |
N/A |
|
|
GBIO |
Generation Bio Co. |
81 |
- |
$0.00 |
$788,000 |
1,944,945 |
0.01% |
-1,274,000 |
0 |
3.273 |
N/A |
|
|
ALGS |
Aligos Therapeutics, Inc. |
82 |
- |
$0.00 |
$685,000 |
83,055 |
0.01% |
-2,624,000 |
0 |
0.115 |
N/A |
|
|
LPTX |
Leap Therapeutics, Inc. |
83 |
- |
$0.39 |
$123,000 |
404,744 |
0% |
-3,247,000 |
-767,431 |
0.678 |
N/A |
|
|
IPSC |
Century Therapeutics, Inc. |
84 |
- |
$0.00 |
$115,000 |
241,684 |
0% |
-690,000 |
-555,776 |
0.441 |
N/A |
|
|
TYRA |
Tyra Biosciences, Inc. |
85 |
- |
$0.00 |
$99,000 |
10,607 |
0% |
-48,000 |
0 |
0.02 |
N/A |
|
|
ACRV |
Acrivon Therapeutics, Inc. |
86 |
- |
$1.22 |
$46,000 |
22,809 |
0% |
-272,000 |
-30,076 |
0.074 |
N/A |
|
|
SRZNW |
Surrozen Equity Warrant Exp... |
87 |
- |
$0.00 |
$25,000 |
833,333 |
0% |
7,000 |
0 |
9.259 |
N/A |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
94 |
Closed |
$0.00 |
$0 |
0 |
0% |
-7,876,000 |
-190,476 |
0 |
N/A |
|
|
ARCT |
Arcturus Therapeutics Ltd |
91 |
Closed |
$6.94 |
$0 |
0 |
0% |
-2,568,000 |
-151,329 |
0 |
N/A |
|
|
FHTX |
Foghorn Therapeutics Inc. |
93 |
Closed |
$0.00 |
$0 |
0 |
0% |
-213,000 |
-45,027 |
0 |
N/A |
|
|
ARVN |
Arvinas Holding Company, Llc |
89 |
Closed |
$7.37 |
$0 |
0 |
0% |
-7,775,000 |
-405,576 |
0 |
N/A |
|
|
PTCT |
PTC Therapeutics, Inc. |
88 |
Closed |
$51.87 |
$0 |
0 |
0% |
-921,000 |
-20,400 |
4.945 |
Biotechnology |
|
|
BMEA |
Biomea Fusion, Inc. |
97 |
Closed |
$2.63 |
$0 |
0 |
0% |
-5,634,000 |
-1,451,990 |
0 |
N/A |
|
|
OPT |
Opthea Ltd |
90 |
- |
$3.41 |
$0 |
2,087,320 |
0% |
-8,537,000 |
-86,302 |
0 |
N/A |
|
|
MRSN |
Mersana Therapeutics, Inc. |
96 |
Closed |
$0.38 |
$0 |
0 |
0% |
-1,553,000 |
-1,086,115 |
0 |
N/A |
|
|
KRYS |
Krystal Biotech Inc |
95 |
Closed |
$133.05 |
$0 |
0 |
0% |
-26,622,000 |
-169,934 |
0 |
N/A |
|
|
PMVP |
Pmv Pharmaceuticals, Inc. |
92 |
Closed |
$0.00 |
$0 |
0 |
0% |
-486,000 |
-322,024 |
0 |
N/A |
|
